This online course provides an in-depth overview of an integrative approach for crystallization development – using models to analyze the SLE behavior of the system, validating the model using relevant experimental data, and systematically synthesizing a crystallization process based on the SLE behavior. Starting with fundamental issues such as solubility and physical properties, we will discuss the relevant theories, methods, experimental techniques, and design methods that have been used in many industrial applications for developing an optimum crystallization process.
Lecture One: Introduction to Crystallization Process Development
Lecture Two: Basics of SLE Behavior and Phase Diagrams
Lecture Three: Thermodynamics-based Conceptual Design of Crystallization Processes
Lecture Four: Synthesis of Crystallization-based Separation Processes
Lecture Five: Crystallization Processes Involving More Complex SLE Behaviors
Lecture Six: Polymorphic Crystallization and Chiral Resolution Process
Lecture Seven: Modeling, Experiments, and Analysis of Experimental Data
Lecture Eight: Design and Scale-up Issues An Overview
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