Towards Genome Engineering in Chinese Hamster Ovary Cells Originally delivered Dec 14, 2010 Developed by: SBE - Society for Biological Engineering Type: Archived WebinarLevel: Advanced PDHs: 1.00 Share This Post: Preview Webinar: Worth over $30 billion, therapeutic proteins, produced by recombinant mammalian cells, have been the fastest growing class of medicines in industrialized nations. Their importance in the health industry in the next decade will be ever greater as their reach expands, improving the quality of life of millions. Critical to the quality of the manufactured product and the robustness of the process is the producing cell. Over three quarters of these products are produced by CHO cells. Advances in DNA sequencing technology in the past few years have afforded the possibility of decoding the entire genome of these cells. Armed with the genome sequence information, one can contemplate specifically altering their sequence and even modifying their genome. This presentation will review genome and sequencing basics, highlight genome information processing, exemplify sequence utility and envision the potential impact of the genome on process advancement and innovation. Presenter(s): Dr. Wei-Shou Hu Prof. Wei-Shou Hu is a Distinguished McKnight University Professor in the Department of Chemical Engineering and Materials Science at the University of Minnesota. Dr. Hu's research in cell culture technology deals with conventional and macroporous microcarriers, suspension culture, and cell-recycling systems. His recent work in cell culture involves the metabolic control of cell's physiological state and genome wide gene expression analysis of their regulation. He co-authored the textbook Bioseparations. He initiated the Engineering Foundation Conferences on Cell Culture Engineering...Read more Once the content has been viewed and you have attested to it, you will be able to download and print a certificate for PDH credits. If you have already viewed this content, please click here to login. Checkout Checkout Do you already own this? Log In for instructions on accessing this content. Pricing AIChE Member Credits 1 AIChE Members $69.00 AIChE Undergraduate Student Members Free AIChE Graduate Student Members Free SBE Members Free Non-Members $99.00 Webinar content is available with the kind permission of the author(s) solely for the purpose of furthering AIChE’s mission to educate, inform and improve the practice of professional chemical engineering. All other uses are forbidden without the express consent of the author(s).