Proteins, Pathways and Genomes: Innovations in Forward Engineering

- Type: Archived Webinar
- Level: Basic
- Duration: 1 hour
- PDHs: 0.00
The development of CRISPR systems to facilitate the editing of genomes has created great excitement and inspired new ideas in engineering biology. While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, genomic accessibility, variety of modifications, and ease of use.
Lysine, predominately used as an animal feed supplement, is a multi-billion-dollar industry however supply is limited due to the cost of current production methods. This webinar will share case studies how Inscripta leveraged its new CRISPR-based technology to design, generate, and screen libraries totaling > 200,000 single edits to improve lysine production in E. coli. Dozens of beneficial edits across the entire genome were discovered to accelerate the Design-Generate-Test-Learn cycle and increase the lysine production by 14,000-fold - ushering in the next era of genome editing.
Attend this webinar to:
- Review the Lysine production improvement data
- Learn how to significantly speed up the DGTL cycle
- Obtain engineering microbial strain at a speed never reach before
- Learn about Inscripta’s Onyx microbial benchtop digital genome editing platform
- Understand a typical workflow on the Onyx Platform
Eric Abbate
Dr. Eric Abbate serves as the Director of Analytical Biochemistry on the Applications Development team. His work primarily focuses on developing and utilizing high-throughput phenotyping workflows to screen libraries generated using the Onyx platform.
Eric’s academic background is in protein structure/function and worked for many years developing enzymes for industrial use at Novozymes prior to joining Inscripta.Read more
Pricing
Individuals
AIChE Members | Free |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
Non-Members | $0.00 |