Proteins, Pathways and Genomes: Innovations in Forward Engineering | AIChE
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Proteins, Pathways and Genomes: Innovations in Forward Engineering

Originally delivered Apr 27, 2021
Source: Inscripta | This webinar is sponsored by Inscripta and reflects their views, opinions, and insights. Attendance is free.
  • Type:
    Archived Webinar
  • Level:
    Basic
  • Duration:
    1 hour
  • PDHs:
    0.00

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Preview Webinar: 

The development of CRISPR systems to facilitate the editing of genomes has created great excitement and inspired new ideas in engineering biology.  While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, genomic accessibility, variety of modifications, and ease of use. 

Lysine, predominately used as an animal feed supplement, is a multi-billion-dollar industry however supply is limited due to the cost of current production methods. This webinar will share case studies how Inscripta leveraged its new CRISPR-based technology to design, generate, and screen libraries totaling > 200,000 single edits to improve lysine production in E. coli.  Dozens of beneficial edits across the entire genome were discovered to accelerate the Design-Generate-Test-Learn cycle and increase the lysine production by 14,000-fold - ushering in the next era of genome editing.  

Attend this webinar to:

  • Review the Lysine production improvement data
  • Learn how to significantly speed up the DGTL cycle
  • Obtain engineering microbial strain at a speed never reach before
  • Learn about Inscripta’s Onyx microbial benchtop digital genome editing platform
  • Understand a typical workflow on the Onyx Platform
Presenter(s): 

Eric Abbate

Dr. Eric Abbate serves as the Director of Analytical Biochemistry on the Applications Development team. His work primarily focuses on developing and utilizing high-throughput phenotyping workflows to screen libraries generated using the Onyx platform.

Eric’s academic background is in protein structure/function and worked for many years developing enzymes for industrial use at Novozymes prior to joining Inscripta.Read more

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Sponsored webinars bring technical information from reputable firms and suppliers to AIChE members. The content reflects the views, opinions, and recommendations of the sponsoring organization. AIChE does not warrant or represent, expressly or by implication, the correctness or accuracy of the content of the information presented. As between (1) the AIChE, the presenter and author(s) of this work, their employers, and their employers' officers and directors, and (2) the user/viewer of this work, the user/viewer accepts any legal liability or responsibility whatsoever for the consequence of its use or misuse. Contact information for attendees of this webinar, including email address, will be shared with the sponsoring firm. You will always have the opportunity to unsubscribe from email from that organization.

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