Proteins, Pathways and Genomes: Innovations in Forward Engineering

The development of CRISPR systems to facilitate the editing of genomes has created great excitement and inspired new ideas in engineering biology.  While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, genomic accessibility, variety of modifications, and ease of use. 

Lysine, predominately used as an animal feed supplement, is a multi-billion-dollar industry however supply is limited due to the cost of current production methods. This webinar will share case studies how Inscripta leveraged its new CRISPR-based technology to design, generate, and screen libraries totaling > 200,000 single edits to improve lysine production in E. coli.  Dozens of beneficial edits across the entire genome were discovered to accelerate the Design-Generate-Test-Learn cycle and increase the lysine production by 14,000-fold - ushering in the next era of genome editing.  

Attend this webinar to:

• Review the Lysine production improvement data
• Learn how to significantly speed up the DGTL cycle
• Obtain engineering microbial strain at a speed never reach before
• Learn about Inscripta’s Onyx microbial benchtop digital genome editing platform
• Understand a typical workflow on the Onyx Platform