The presentation will summarize our work on the development of semi-analytical expressions to accurately calculate the potential landscape, including van der Waals interactions, of a Janus particle with non-uniform coating thickness above a solid boundary. The effects of both non-uniform coating thickness and van der Waals interactions significantly influence the potential landscape of the particle, particularly in high ionic strength solutions, where the particle samples positions very close to the solid boundary. Although Brownian dynamics simulations that we previously developed help to predict trajectories and complement experiments, the semi-analytical equations developed herein facilitated simple, accurate, and less computationally expensive characterization of conservative interactions experienced by a Janus particle near a boundary.
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