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A Quality by Design Approach to Scale-up of the ...

Conference Presentation

AIChE Annual Meeting

November 7, 2010

The melt-spray-congeal (MSC) process is a rotary atomization technique for the production of a multiparticulate pharmaceutical dosage form. The final...
A System Approach to Astrocytoma Progression

Conference Presentation

AIChE Annual Meeting

November 8, 2010

Astrocytomas are brain cancers that account for 75% of neuroepithelial tumors. Accurate diagnosis is required for adequate treatment and assessing...
Accelerated Development and Improved Process Operations ...

Conference Presentation

AIChE Annual Meeting

November 8, 2010

This talk will focus on the use of advanced multivariate latent variable models to aid the accelerated development of the product and the process, as...
Achieving QM Accuracy at a Fraction of Computational Cost: ...

Conference Presentation

AIChE Annual Meeting

November 10, 2010

There is a multitude of possible formulation pathways for pharmaceutical compounds among which polymorph, solvate, salt and cocrystal formation are...
Aging of Biomass Fast Pyrolysis-Oil and Process Strategies ...

Conference Presentation

AIChE Annual Meeting

October 19, 2011

Fast pyrolysis bio-oils are unstable due to a variety of factors, the most important being the high concentration of reactive oxygen-functionalized...
Alternative Fuels from Coal and Biomass: Biochemical ...

Conference Presentation

AIChE Annual Meeting

November 8, 2009

The volatility of oil prices, the large proportion of oil importation, and the massive contribution of greenhouse gases from the transportation...
An Integrated Quality-by-Design (QbD) Approach towards ...

Conference Presentation

AIChE Annual Meeting

November 10, 2010

Combined Quality-by-Design and computer simulation approaches (discrete element method and computational fluid dynamics) are presented to...
Application of Modeling to Scale-up Liquid Mixing Processes

Conference Presentation

AIChE Annual Meeting

November 11, 2009

Scale-up of liquid mixing is usually done empirically without considering the several factors like dissolution theory, equipment differences between...
Application of QbD Principles to Analytical Methods

Conference Presentation

AIChE Annual Meeting

November 8, 2009

The same QbD Principles applied to the design of manufacturing processes are applicable to the design of analytical methodology. QbD elements such as...
Automated Metabolic Network Reconstruction: Method, ...

Conference Presentation

AIChE Annual Meeting

November 8, 2010

Genome-wide metabolic network reconstruction has proved to be a powerful tool for system-level study of whole-cell metabolisms. A great amount of...
Automation and Control of Drug-On-Demand Technology

Conference Presentation

AIChE Annual Meeting

October 16, 2011

After the implementation of initiatives such as PAT and QbD, there has been a drive towards efficient manufacturing in the pharmaceutical industry...
Biological Synthesis of Fuels and Chemicals

Archived Webinar

Jul 22, 2010

Global energy and climate problems have stimulated increased efforts in synthesizing fuels and chemicals from renewable resources. Compared to the traditional biofuel, ethanol, higher alcohols offer...