Society for Biological Engineering (SBE) SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.
Food, Pharmaceutical & Bioengineering Division (FP & BE) The FP&BE division coordinates AIChE's activities in the fields of food, pharmaceuticals, and bioengineering.
Forest Bioproducts Division (FBP) The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.
Challenges, Opportunities, and Scientific Aspects of Implementing PAT In Biopharmaceuticals Conference PresentationAIChE Annual MeetingOctober 19, 2011As an essential milestone for both the cGMP for the 21 st Century and the recent pharmaceutical quality regulatory initiatives (Q8/Q9/Q10), the 2004...
Managing Uncertainty In Design Space Conference PresentationAIChE Annual MeetingOctober 19, 2011Design of experiments, followed by numeric and graphical optimization, is frequently used by engineers to optimize a process, and to define a design...
Green and High Efficient Enzyme Hydrolysis Process for Sweet Sorghum Bagasse Conference PresentationAIChE Annual MeetingOctober 19, 2011In order to improve enzymatic hydrolysis efficiency, several approaches including liquid hot water (LHW) pretreatment, adding surfactant, magnetic...
Scale and Bioreactor Design Translation for Rocking Bag Bioreactors Conference PresentationAIChE Annual MeetingOctober 19, 2011Scale and Bioreactor Design Translation for Rocking Bag Bioreactors. The translations of scale and bioreactor designs for disposable rocking bag...
Simultaneous Extracellular Polymeric Substance (EPS) and Lipid Production by Activated Sludge Via Fermentation of Glucose Conference PresentationAIChE Annual MeetingOctober 19, 2011The use of activated sludge microflora to convert sugars, derived from the hydrolysis of lignocellulose biomass, into lipids for biofuel production...
Use of Single-Use Technologies In Downstream Purification of Mabs - A Case Study Conference PresentationAIChE Annual MeetingOctober 19, 2011The employment of single-use technologies in the downstream processing of biologics in general and monoclonal antibodies in particular is gaining...
The Influence of Crystals, Particles and Powders On the Performance of Dry Powder Inhalers Conference PresentationAIChE Annual MeetingOctober 19, 2011This presentation focuses on some key developments in understanding the relationships between the governing properties of DPIs and how these properties can be harnessed to develop designer formulation systems for DPIs.
Effect of Steam Explosion On Degradability and Accessiblity of Loblolly Pine In Bioethanol Applications Conference PresentationAIChE Annual MeetingOctober 19, 2011Abstract Among the various biomass pretreatment methods, steam explosion is one of the most widely used due to its cost-effective disruption of the...
Biofuels Manufacturing: From Feedstocks to Manufacturing and End-Product Quality Control Conference PresentationAIChE Annual MeetingOctober 19, 2011Biofuels quality is related to the inherent of feedstock materials (RMs) and operating conditions used in their production. However to be used as...
Design Space Definition Using a Variational Bayes' Approximation Conference PresentationAIChE Annual MeetingOctober 19, 2011The design space may be interpreted as the constrained region of the key manufacturing parameters space which provides assurance of quality of a drug...
Quality by Design for DPIs -A Regulatory Perspective Conference PresentationAIChE Annual MeetingOctober 19, 2011Inhalation Powders have become an important dosage form in developing products for delivery to the lungs. Since the approval of the first DPI in the...
BIOCORE - On a Paradigm for the Design and Synthesis of Real-Life Biorefineries Conference PresentationAIChE Annual MeetingOctober 19, 2011As oil is a fast depleting resource (BP, 2010), much is expected by the production of biofuels as valid options to replace fossil-oil transportation...
Effects of Reaction Conditions On the Acid-Catalyzed Hydrolysis of Miscanthus Dissolved In An Ionic Liquid Conference PresentationAIChE Annual MeetingOctober 19, 2011Miscanthus, a perennial grass, is an attractive biofuel feedstock compared with corn and poplar due to its high energy yield per hectare and low...
A Data-Driven Modeling Approach Using the Design of Dynamic Experiments Methodology In Calculating the Design Space of Batch Pharmaceutical Processes Conference PresentationAIChE Annual MeetingOctober 19, 2011The development of fundamental models for fed-batch pharmaceutical processes range from very challenging to almost impossible as not all the inner...
Aging of Biomass Fast Pyrolysis-Oil and Process Strategies to Produce Stable Pyrolysis Oils Conference PresentationAIChE Annual MeetingOctober 19, 2011Fast pyrolysis bio-oils are unstable due to a variety of factors, the most important being the high concentration of reactive oxygen-functionalized...
Incremental Disassembling of Woody Biomass and Production of Biochemicals Conference PresentationAIChE Annual MeetingOctober 19, 2011Woody biomass is a reliable renewable source of raw materials for energy and chemicals. Woody biomass is structurally composed of cellulose, lignin,...
Change of Structure of Corncob with Dilute Acid and Lime Pretreatment and a Potential Process for Xylose Co-Production of Cellulosic Ethanol Conference PresentationAIChE Annual MeetingOctober 19, 2011Degree of polymerization (DP) of cellulose is considered an important factor to effect on the conversion of Lignocellulose. The higher DP of...
Bioconversion of Brown Seaweed Into Mixed Ketones Through the Carboxylate Platform Processing Conference PresentationAIChE Annual MeetingOctober 19, 2011The Carboxylate Platform, also known as the MixAlco TM process, is an acidogenic fermentation process using mixed culture inoculums, which offers...
Inhibitory Effects of Lignocellulosic Degradation Compounds From Hydrolysate On Microbial Oil Production Conference PresentationAIChE Annual MeetingOctober 19, 2011Inhibitory effects of lignocellulosic degradation compounds from hydrolysate on microbial oil production. Jijiao Zeng, Xiaochen Yu, Yubin Zheng,...
A Model-Assisted Tool for the Characterization of Char In Biomass Pyrolysis and Biomass Catalytic Pyrolysis Conference PresentationAIChE Annual MeetingOctober 18, 2011Coke formation appears as a reason for catalyst deactivation and results in undesirable product selectivity in biomass pyrolysis. However, there is...
Triacylglycerol Production From Corn Stover Silage Using a Xylose-Fermenting Rhodococcus Opacus Strain Conference PresentationAIChE Annual MeetingOctober 18, 2011Background: Biodiesel, monoalkyl esters of long-chain fatty acids attached to short-chain alcohols derived from triacylglycerols (TAGs), can be...
Study of Culture Strategies of Microalgae In a Continuous Photobioreactor System for Biofuel Production Conference PresentationAIChE Annual MeetingOctober 18, 2011The development of new biomass sources for alternative fuels has become a subject of increasing importance as the nation strives to resolve the...
Realizing the Potential of Advanced Biofuels Conference PresentationAIChE Annual MeetingOctober 18, 2011Advanced biofuels or drop-in fuels is the terminology used to refer to hydrocarbon fuels that are direct replacements or supplements for existing...
Mechanistic Investigation of Drug Release From Asymmetric Membrane Tablets Conference PresentationAIChE Annual MeetingOctober 18, 2011An asymmetric membrane (AM) tablet was developed for a soluble model compound to study the in vitro drug release mechanisms in challenge conditions,...
Cellobiose Hydrolysis Using Acid-Functionalized Nanoparticles Conference PresentationAIChE Annual MeetingOctober 18, 2011Mineral acids have been used effectively for the pretreatment of cellulosic biomass to improve sugar recovery and promote its conversion to ethanol;...
Effect of Column Temperature On HPLC Separation of Acetic Acid and Levulinic Acid Conference PresentationAIChE Annual MeetingOctober 18, 2011High performance liquid chromatography (HPLC) is a routine method in the analysis of degradation products in the prehydrolysate or the hydrolysis...
Co-Utilization of Methane In Steam-Biomass Gasification Using Concentrated Solar Energy Conference PresentationAIChE Annual MeetingOctober 18, 2011Presented is a novel gasification application where biomass is steam-gasified and natural gas is steam-reformed simultaneously in a solar reactor...
Transferring Monitoring Models Between Different Scales Through Multivariate Statistical Techniques Conference PresentationAIChE Annual MeetingOctober 18, 2011The challenge of transferring a process monitoring model across different scales is a different problem than the one addressed in previous studies...
Catalytic Isomerization/Dehydration of Sugars On Functionalized CNT-Metal Oxide Hybrids At the Liquid-Liquid Interface of Water/Oil Emulsions Conference PresentationAIChE Annual MeetingOctober 18, 2011The conversion of C5-C6 sugars into 2-furfural (FA) and 5-hydroxymethylfurfural (HMF) have been considered as key intermediate step in the production...
Improving Corn Stover Reactivity In Low Severity Pretreatment Through Deacetylation and Disc-Refining Conference PresentationAIChE Annual MeetingOctober 18, 2011The current “state-of-art” dilute acid pretreatment to produce bio-ethanol from corn stover requires severe conditions to overcome biomass...
Optical Coherence Tomography: A New PAT-Tool for Fast and Non-Destructive Analysis of Tablet Coating Quality Conference PresentationAIChE Annual MeetingOctober 18, 2011Optical coherence tomography (OCT) is a non-invasive imaging technique allowing fast and high-quality cross-sectional imaging of semi-transparent and...
Conversion of Cellobiose Into Glucose At near-Neutral pH Using a Recyclable Heterogeneous Catalyst Conference PresentationAIChE Annual MeetingOctober 18, 2011Strong acids under severe reaction conditions are known to rapidly hydrolyze cellulose with moderate selectivity towards glucose; however, enzymes in...
Point of Use Recyclable Bioreactor System for Bio-Agricultural Applications Conference PresentationAIChE Annual MeetingOctober 18, 2011Farmers have long been respected for their self-sufficiency, acting as primary producers for society. Yet as time progresses, productivity demands...
Biological Conversion of Algefiber® (Seaweed Sludge) to Carboxylic Acids for Chemical Upgrading to Higher Alcohols Liquid Biofuel Conference PresentationAIChE Annual MeetingOctober 18, 2011Concern about biofuel production from renewable resources has increased globally. Among different approaches to produce biofuels, the MixAlco ™...
Understanding the Impact of the Properties of Raw Materials Onto Product Quality Using JR-PLS Conference PresentationAIChE Annual MeetingOctober 18, 2011Multiple proposals are found in literature to analyze the impact of raw materials onto product using data analysis. From the methods proposed, the L-...
The Role of Oxygen In the Stability of Biomass Pyrolysis Oils Conference PresentationAIChE Annual MeetingOctober 18, 2011One of the major challenges in the conversion of biomass pyrolysis to high value products and fuels is the poor stability of the oils. Biomass...
Poly(oxymethylene) Dimethyl Ethers As Components of Tailored Diesel Fuel - Properties, Synthesis and Purification Concepts Conference PresentationAIChE Annual MeetingOctober 18, 2011Poly(oxymethylene) Dimethyl Ethers as components of tailored diesel fuel - properties, synthesis and purification concepts Jakob Burger 1* , Markus...
Modified AnoporeTM Hybrid Membranes for the Microfiltration of Cellulose Acid Hydrolysis Mixtures Conference PresentationAIChE Annual MeetingOctober 18, 2011Three classes of nonfouling substances, poly[poly(ethylene glycol) methyl ether methacrylate] (POEM), poly(sulfobetaine methacrylate) (PSBMA), and...
Feedstock Mixture Effects On Sugar Monomer Recovery Following Dilute Acid Pretreatment and Enzymatic Hydrolysis Conference PresentationAIChE Annual MeetingOctober 18, 2011Feedstock Mixture Effects on Sugar Monomer Recovery Following Dilute Acid Pretreatment and Enzymatic Hydrolysis Michael Brodeur-Campbell 1 , Jordan...
Pyrolytic Pathways to Advanced Biofuels Conference PresentationAIChE Annual MeetingOctober 18, 2011Pyrolysis is the thermal conversion of carbonaceous materials in the absence of molecular oxygen to liquids, solids and gases. In the most general...
The Production of Fuel Grade Butanol From Algal Carbohydrates Utilizing a Hybrid Biological and Chemical Process Conference PresentationAIChE Annual MeetingOctober 18, 2011Butanol has the potential to become a superior renewable fuel, either as a mixture with petroleum derived gasoline or as a stand-alone, neat fuel...
Alkaline Deacylation of Corn Stover to Reduce Toxicity of Prehydrolyzates and Improve Enzymatic Hydrolysis Conference PresentationAIChE Annual MeetingOctober 18, 2011Hydrolysates from dilute acid pretreatment of biomass contain various biomass degradation products which are inhibitory to enzymes and toxic to...
PAT Application and Validation of Online Particle Sizing Measurement for Controlling a Critical Quality Attribute Conference PresentationAIChE Annual MeetingOctober 18, 2011In accordance with ICH Q8/9/10 and the FDA QbD initiative, companies are adding more and more PAT equipment, installing more sophisticated control...
The Role of Acidic Catalyst Support On the Catalytic Upgrading of Bio-Oils Conference PresentationAIChE Annual MeetingOctober 18, 2011Catalytic conversion of bio-oil vapor has attracted considerable interest as a promising pathway for upgrading. In this work, the reaction of anisole...
Insights Into Lactate Metabolism Through Multivariate Analysis of Cell Culture Bioprocess Data Conference PresentationAIChE Annual MeetingOctober 18, 2011Multivariate data analysis has recently emerged as a critical tool to gain fundamental understandings of process characteristics, and thus assisting...
Membrane Filtration of Lignocellulosic Hydrolyzates: Comparison of Crossflow and Dead-End Microfiltration Conference PresentationAIChE Annual MeetingOctober 18, 2011Depleting oil reserves have encouraged the development of technologies to harness the natural resources to sustain the energy needs. Renewable...
Synthesis of Green Diesel Fuel From Fatty Acid Feedstocks Via Electrochemical Hofer-Moest Decarboxylation Conference PresentationAIChE Annual MeetingOctober 18, 2011Production of biodiesel by esterification or transesterification of long-chain fatty acids is a well known process, but the fuel product has...
Study On the Pyrolysis Characteristics of Biomass Compositions In Medical Wastes Conference PresentationAIChE Annual MeetingOctober 18, 2011Study on the Pyrolysis Characteristics of Biomass Compositions in Medical Wastes DENG Na * , Wang Weiwei, ZHANG Yu-feng, MA Hong-ting （School of...
Comparison of Chemical and Biological Delignification of Cardboard Conference PresentationAIChE Annual MeetingOctober 18, 2011Some processes aimed to biofuels production, use lignocellulosic wastes as feedstocks for fermentative conversion. If this is the case, pretreatment...
Reducing Process Complexity for Cellulosic Ethanol Conference PresentationAIChE Annual MeetingOctober 18, 2011Much of the process complexity and high capital costs associate with cellulosic ethanol (dilute acid hydrolysis as a pretreatment and enzymatic...
Lignin Depolymerization and Deoxygenation In Ionic Liquids Conference PresentationAIChE Annual MeetingOctober 18, 2011Lignin, an amorphous aromatic biopolymer that comprises up to 30% of plant matter, was dissolved and depolymerized in ionic liquids under acidic...
Which Fractionation Process Can Overcome Techno-Economic Hurdles of a Lignocellulosic Biorefinery? Conference PresentationAIChE Annual MeetingOctober 18, 2011Lignocellulosics are considered as feed stock for transportation fuels and chemicals because they address two pressing global issues; climate change...
Mechanistic Models and Computer Software for Quality by Design In Formulation of Modified Release Dosage Forms Conference PresentationAIChE Annual MeetingOctober 18, 2011Modified release dosage forms (MRDFs) can be designed and manufactured in various shapes and structures using different materials. Depending on the...
Integration of a Membrane Based Extraction Process Into a Lignocellulosic Biorefinery Conference PresentationAIChE Annual MeetingOctober 18, 2011In the future, it is anticipated that multi-product biorefineries will be used to convert lignocellulosic biomass to fuels and chemicals, in which,...
An Integrated Lipid-Based Platform for “Drop-In” Fuel Biorefinery Conference PresentationAIChE Annual MeetingOctober 18, 2011A major challenge in developing biorefinery is that the availability of biomass often limits the scale of the plant thus the feasibility of an...
De-Risking Scale-up of a High Shear Wet Granulation Process Using Latent Variable Modeling and near Infrared Spectroscopy Conference PresentationAIChE Annual MeetingOctober 18, 2011In the development of wet granulated drug products, two primary sources of variance (disturbance) include the operational scale of the high shear wet...
Oxidation of Polyols Using Au-Pd and Au-Pt Alloy Supported Nanocrystals Conference PresentationAIChE Annual MeetingOctober 18, 2011Oxidation of polyols using Au-Pd and Au-Pt alloy supported nanocrystals Peter Miedziak a , Gemma L. Brett a , Yulia Ryabenkova a , Nikolaos...
Structural Characterization of AHP-Pretreated Biomass Conference PresentationAIChE Annual MeetingOctober 18, 2011Alkaline hydrogen peroxide (AHP) pretreatment is exceptionally well-suited to grasses, yielding high digestibilities at low enzyme loadings, while...
Construction of Efficient Gram-Negative Biocatalysts for Lignocellulose Conversion Conference PresentationAIChE Annual MeetingOctober 18, 2011Research within the Great Lakes Bioenergy Research Center aims to better understand the bottlenecks associated with bioconversion of lignocellulose...
CMC Reviewer Expectations for ANDAs Using QbD Approaches Conference PresentationAIChE Annual MeetingOctober 18, 2011There has been an increase in science and risk-based approaches under the Quality by Design paradigm in new drug submissions to the FDA. There are...
Acetic Acid Removal From the Hydrolysate Using Reactive Extraction In a Membrane Extractor/Reactor Conference PresentationAIChE Annual MeetingOctober 18, 2011Production of bioethanol from lignocellulosic biomass requires pretreatment of the biomass to hydrolyze hemicellulose, separate lignin and reduce...
Sub- and Supercritical Water Based Processes for Conversion of Algae Biomass to Fuels and Green Chemicals – A Review Conference PresentationAIChE Annual MeetingOctober 18, 2011Sub- and Supercritical Water Based Processes for Conversion of Algae Biomass to Fuels and Green Chemicals – A Review Philip A. Marrone and Bryan V...
Supercritical CO2 Extraction for Algal Biodiesel Production Conference PresentationAIChE Annual MeetingOctober 18, 2011SC-CO2 is cleaner green technology for extraction of algal lipids/oils for algal biodiesel production. This work offers an optimized method for the...
Isoconversional Methods Applied to Kinetic Modeling Oxidative Alkaline Pretreatment of Sugarcane Bagasse Conference PresentationAIChE Annual MeetingOctober 18, 2011Delignification (decrease of lignin content) has shown to be a valid method to significantly increase lignocellulosic feedstocks digestibility. This...
Production of Concentrated Monosaccharride Solutions From Biomass Using CO2-H2O Mixtures At Varying Temperatures Conference PresentationAIChE Annual MeetingOctober 18, 2011Sustainably producing concentrated solutions of monosaccharrides from biomass is a key bottleneck in the conversion of lignocellulosic biomass to...
Heterogeneous Catalysts in the Dehydration of Fructose to HMF Conference PresentationAIChE Annual MeetingOctober 18, 2011Several crucial steps in the upgrading of biomass-derived raw materials involve acid catalyzed reactions, such as the hydrolysis of cellulose or the...
Evaluation of Membrane Separations Opportunities within Lignocellulosic Biorefining Processes: Tailoring Membrane Properties Conference PresentationAIChE Annual MeetingOctober 18, 2011Evaluation of Membrane Separations Opportunities within Lignocellulosic Biorefining Processes: Tailoring Membrane Properties Jennifer Leberknight,...
Cellulose Extraction From Rice Hulls Using Ionic Liquids Conference PresentationAIChE Annual MeetingOctober 18, 2011Over one fifth of calories consumed by humanity are from rice. Consequently, vast quantities of rice hulls are disposed of as waste, since the hull...
QbD for Generic MR Drug Products Conference PresentationAIChE Annual MeetingOctober 18, 2011The Office of Generic Drugs ensures the therapeutic equivalence and quality of generic drug products. This is based principally upon a regulatory...
Ab-Initio Study of Glycerol Dehydration Mechanisms with Explicit Solvent Treatment Conference PresentationAIChE Annual MeetingOctober 18, 2011Glycerol produced as a waste product in biodiesel production has interesting potential as a low-cost biomass-derived feedstock for chemical...
Effect of Transition Metal Catalyst On Lignin Oxidation During Alkaline Hydrogen Peroxide Pretreatment Conference PresentationAIChE Annual MeetingOctober 17, 2011Biomass lignocellulose can be used as feedstock for bioethanol production, and a pretreatment is necessary for achieving high ethanol yield and...
Energy Optimization of Hydrogen Production From Biomass Conference PresentationAIChE Annual MeetingOctober 17, 2011Energy optimization of Hydrogen production from biomass Mariano Martín a,b , Ignacio E. Grossmann b [1] mariano.m3@usal.es ; grossmann@cmu.edu a...
Improved Ethanol Production Through Anaerobic Thermophilic Co-Culture From Various Carbohydrates Conference PresentationAIChE Annual MeetingOctober 17, 2011Saccharification of fermentable sugars is one of the most critical steps in producing bio-ethanol from lignocellulosics through Consolidate...
QUALITY by Design (QBD), Biopharmaceutical Manufacture Conference PresentationAIChE Annual MeetingOctober 17, 2011In the biopharmaceutical industry, consistently manufacturing a safe and high quality protein drug substance can be challenging. Recently, a...
Pyrolysis Vapors Upgrading Using Metal Oxides Conference PresentationAIChE Annual MeetingOctober 17, 2011Pyrolysis Vapors Upgrading using Metal Oxides Ayman M. Karim 1 , Donghai Mei 1 , Vanessa Lebarbier 1 , Changjun Liu 1,2 and Yong Wang 1,2 1 Pacific...
Role of Enzyme Blend Composition, Biomass Particle Size and Solids Loading On Pretreated Biomass Saccharification Efficiency Conference PresentationAIChE Annual MeetingOctober 17, 2011One of the limitations of screening enzyme combinations using microplate based assays (Gao et al. 2010, Bioresour Technol 101, 8:2770) is that these...
Milking Lipids From Green Alga: Feasibility of Using Biocompatible Solvents to Extract Lipids From Living Cells Conference PresentationAIChE Annual MeetingOctober 17, 2011A key hurdle in realizing commercial-scale production of biodiesel from cultured algae is efficient harvesting/dewatering of algal cells. In order to...
Flow and Transport Properties In High-Solids Biomass Slurries Conference PresentationAIChE Annual MeetingOctober 17, 2011Economic biochemical conversion of cellulose to sugars necessitates minimal addition of water to biomass slurries during conversion, resulting in...
Novel Reactor Design for Conversion of Waste Oils to Biodiesel Conference PresentationAIChE Annual MeetingOctober 17, 2011Biodiesel is a renewable, carbon-neutral fuel that can ease pressure on the world’s dwindling supply of oil and petroleum diesel. This research...
Binary Diffusion Coefficients of Biomass-Based Carbochemicals In Subcritical Water Using Chromatographic Peak Broadening Technique Conference PresentationAIChE Annual MeetingOctober 17, 2011Carbochemicals such as furfural and HMF are very useful as intermediates in the production of various chemicals and polymers that have numerous food...