Pharmaceutical Development

Technical Entity Trends: Artificial Intelligence Marks A New Drug Lifecycle

June
2019
Technical Entity Trends
Expedito Segovia
A wave of change is spreading across many industries due to technological advances enabled by artificial intelligence (AI) and automation. The pharmaceutical industry is no exception and is harnessing AI tools for new drug discovery and development...

Meet Process Engineer Jacob Albrecht

November 21, 2018

Jacob Albrecht discusses the challenging but enjoyable road to manufacturing new medicines, and the creative aspects of process engineering.

Meet Process Engineer Yangmu Liu

June 28, 2018

Process engineers are bringing improved manufacturing to the pharmaceuticals industry. Read one process engineer's take on her work in the industry.

Is Synthetic Biology Having a Moment?

February 15, 2019

Suddenly, synthetic biology is being discussed a lot beyond the walls of academia and the pages of scientific journals. Today, it abounds in the mainstream press.

CEP: News Update

February
2019
News Update
A Hub for Appalachia’s Emerging Petrochemical Industry A recent U.S. Dept. of Energy (DOE) report highlights the potential benefits of Appalachia Development Group’s (ADG) proposed infrastructure project, the over $3 billion Appalachian Storage and...
Chimeric antigen receptor (CAR) T-cell therapy uses T-cells gathered from the patient’s own blood. The T-cells are engineered and then infused back into the patient to target and attack cancer cells.

CAR T-Cell Therapy Individualizes Cancer Treatment

December 27, 2018

The market for chimeric antigen receptor (CAR) T-cell therapy is projected to be valued at almost $300 million by the end of 2018, and this number is expected to grow annually by 32% for the next decade.

CEP: News Update

August
2018
News Update
New CRISPR Findings Raise Concerns Before Technology’s Clinical Debut A pair of studies that investigated the effect of CRISPR-Cas 9 on a key protein that regulates cell growth and protects against cancer has sent shockwaves through the growing...

IQ Consortium Enabling Technologies for Pharma

Conference Presentation
AIChE Annual Meeting
November 9, 2015
The International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) is a technically-focused organization of pharmaceutical...

Quality by Design in Pharmaceutical Development

Conference Presentation
AIChE Annual Meeting
November 7, 2010
More than 70% of the prescriptions in the US are now filled with generic products, and therefore, the industry has the responsibility to continue to...

Engineering Cancer-Fighting T Cells

October
2017
SBE Special Section
Eugenia Zah, Yvonne Y. Chen
Adoptive T-cell therapy is a personalized cancer treatment that has the potential to cure previously untreatable malignancies. Researchers are applying techniques in biomolecular engineering and synthetic biology to the development of next-generation therapeutic T cells with improved safety and efficacy against a variety of cancers.

A Materials Approach to Vaccines as Therapies

October
2017
SBE Special Section
Neil Dold, Christopher M. Jewell
The widespread adoption of vaccines over the last two centuries has transformed medicine by preventing infectious disease. In the future, so-called therapeutic vaccines could be used as effective treatments for cancer and autoimmune disorders — ushering in a new era of medicine.
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