The Future of Drug Delivery Innovations in Biotechnology and Biomaterials Archived Webinar Feb 12, 2014 Advanced drug delivery systems are having an enormous impact on human health.
Predicting Buffer and Media Preparation Times for Single-Use Mixer Scale-Up Conference PresentationAIChE Annual MeetingNovember 7, 2013As the implementation of single-use mixing technologies in biopharmaceutical manufacturing operations expands , scaling and mix time predictability...
Force to Death and New Life, Some with Programming Vitality Conference PresentationAIChE Annual MeetingNovember 4, 2013Regenerative medicine is the quest to provide biological or hybrid synthetic-biological materials that can enable or facilitate therapeutic...
Microengineered Hydrogels for Stem Cell Bioengineering and Tissue Regeneration Archived Webinar Aug 23, 2011 Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various tissue engineering...
Biomaterials for Stem Cell Tissue Engineering Archived Webinar Apr 5, 2011 Stem cells have become a promising cell source in the tissue engineering field. Intense studies have been focused at the cell and molecular biology levels on understanding the relationship between stem cell growth and terminal differentiation in an effort to control these processes. Recent...
Cell Therapy Bioprocessing Archived Webinar Feb 8, 2011 As cellular therapies are advancing through clinical development and getting closer to market, close collaborations between stem cell biologists, clinical cell processing technologists, and bioengineers will be required for effective commercialization of this new class of drugs. New cell production...
Molecular Elucidation and Engineering of Stem Cell Microenvironments Archived Webinar Jan 21, 2010 Stem cells are defined by their capacities for self-renewal and differentiation into one or more cell lineages, and these processes are regulated by signals from the stem cell microenvironment, or niche, in various tissues throughout organismal development and adulthood. These niches control cell...
Technical Entity Trends: A Cure May Stem From Your Cells February2017Technical Entity TrendsGabriel Levesque-TremblayBefore her first birthday, Layla Richards was diagnosed with an aggressive form of leukemia. After chemotherapy and a bone marrow transplant failed to cure her, she was treated in 2015 with engineered T-cells. The treatment eradicated all traces of...
Nanostraw Tool Samples Cells without Destruction February 23, 2017Using nanostraws, scientists can now sample cell contents without disrupting a cell's natural processes.
Little Bio-Machinery to Solve Grand Challenges January 3, 2017As we approach ICBE 2017, which begins this weekend in San Diego, we look back at some of the exciting research that figured among 2016's highlights and look forward to the new developments to be unveiled at ICBE 2017.
Major Public Database to Fuel Personalized Medicine July 8, 2016The U.S. government announced this week that it is putting aside $55 million to create a public database with health information on about one million volunteers.
Renowned Scientist and AIChE Member Frances Arnold Profiled on NPR December 17, 2014Any short list of cutting-edge engineers will likely include Caltech’s Frances Arnold, a pioneer in protein engineering.
Creating an Internet for Genomic Information December 24, 2014A group called the Global Alliance for Genomics and Health (known as the Global Alliance) wants to maximize the use of genetic data by cr
Stem Cell Engineering 101 November2010SBE Special SectionJonathan MonkStem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and drug-screening platforms will require a combination of sound science...
Developing Cell Therapy Biomanufacturing Processes November2010SBE Special SectionJon A. RowleyEstablishing scalable technology platforms that allow for varying levels of production throughout the different stages of clinical testing can minimize process development timelines, drug-comparability risks, and — ultimately — costs.
Engineering a Better Way to Heal Broken Bones November2010SBE Special SectionMatthew B. MurphyIntegrating mesenchymal stem cells and biomaterials shows promise for treating traumatic skeletal injuries via bone tissue engineering.
Scaling Up Research to Commercial Manufacturing November2010SBE Special SectionErika LapinskasThe production of stem-cell-based therapeutic products in large quantities is more complex than manufacturing molecular drugs. Scale-up and scale-out challenges arise related to the type of stem cell, cell expansion and banking, sterile handling,...