Stem Cell Engineering

Microengineered Hydrogels for Stem Cell Bioengineering and Tissue Regeneration

Archived Webinar
Aug 23, 2011
Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various tissue engineering...

Biomaterials for Stem Cell Tissue Engineering

Archived Webinar
Apr 5, 2011
Stem cells have become a promising cell source in the tissue engineering field. Intense studies have been focused at the cell and molecular biology levels on understanding the relationship between stem cell growth and terminal differentiation in an effort to control these processes. Recent...

Cell Therapy Bioprocessing

Archived Webinar
Feb 8, 2011
As cellular therapies are advancing through clinical development and getting closer to market, close collaborations between stem cell biologists, clinical cell processing technologists, and bioengineers will be required for effective commercialization of this new class of drugs. New cell production...

Molecular Elucidation and Engineering of Stem Cell Microenvironments

Archived Webinar
Jan 21, 2010
Stem cells are defined by their capacities for self-renewal and differentiation into one or more cell lineages, and these processes are regulated by signals from the stem cell microenvironment, or niche, in various tissues throughout organismal development and adulthood. These niches control cell...

Technical Entity Trends: A Cure May Stem From Your Cells

February
2017
Technical Entity Trends
Gabriel Levesque-Tremblay
Before her first birthday, Layla Richards was diagnosed with an aggressive form of leukemia. After chemotherapy and a bone marrow transplant failed to cure her, she was treated in 2015 with engineered T-cells. The treatment eradicated all traces of...

Nanostraw Tool Samples Cells without Destruction

February 23, 2017
Using nanostraws, scientists can now sample cell contents without disrupting a cell's natural processes. The new tool was developed by researchers at Stanford, and it is hoped...

Little Bio-Machinery to Solve Grand Challenges

January 3, 2017
As we approach ICBE 2017, which begins this weekend in San Diego, we look back at some of the exciting research that figured among 2016's highlights and look forward to the new...

Creating an Internet for Genomic Information

December 24, 2014
A group called the Global Alliance for Genomics and Health (known as the Global Alliance ) wants to maximize the use of genetic data by creating a responsible way to share it with...

Stem Cell Engineering 101

November
2010
SBE Special Section
Jonathan Monk
Stem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and drug-screening platforms will require a combination of sound science...

Engineering a Better Way to Heal Broken Bones

November
2010
SBE Special Section
Matthew B. Murphy
Integrating mesenchymal stem cells and biomaterials shows promise for treating traumatic skeletal injuries via bone tissue engineering.

Developing Cell Therapy Biomanufacturing Processes

November
2010
SBE Special Section
Jon A. Rowley
Establishing scalable technology platforms that allow for varying levels of production throughout the different stages of clinical testing can minimize process development timelines, drug-comparability risks, and — ultimately — costs.

Scaling Up Research to Commercial Manufacturing

November
2010
SBE Special Section
Erika Lapinskas
The production of stem-cell-based therapeutic products in large quantities is more complex than manufacturing molecular drugs. Scale-up and scale-out challenges arise related to the type of stem cell, cell expansion and banking, sterile handling,...
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