David Segal on Epigenetic Editing July 11, 2019Hear David's predictions for the future of gene editing, and learn about his work to develop epigenetic editing as a therapy for neurological disorders.
CEP: News Update July2019News UpdateAI Gives the Fragrance Industry a New Nose In recent years, artificial intelligence (AI) has found its way into the fragrance industry. The union sometimes seems at odds with the world of scent, which is often tied to human emotion. Yet, as the...
A Chat with Twist Bioscience's Emily Leproust on DNA Synthesis May 30, 2019Twist Bioscience CEO, cofounder, and director Emily Leproust discusses the company's work and the promising future of synthetic biology.
Robert S. Langer, Massachusetts Institute of Technology: The Future of Chemical Engineering September 13, 2018Bob Langer of MIT shares his predictions on where he sees the profession of chemical engineering heading over the next 25 years.
Mo Ebrahimkhani on CRISPR Technologies [Interview] October 25, 2018Mo looks at the importance of CRISPR technology and what advances it may help us unlock.
Editing Genes One Sequence at a Time July 17, 2018Take a look at the advantages, drawbacks, and future of CRISPR-Cas9, which has transformed synthetic bioengineering.
SBE Special Section: Epigenetics (Complete 29-Page Section) September2018SBE Special SectionEpigenetics Making a Mark; The Untapped Information of the Epigenome; Unlocking Acces to DNA in Chromatin; Single-Cell Epigenetic Technology and Applications; Influence of Epigenetics on Bioprocessing
Epigenetics: Making a Mark September2018SBE Special SectionGabriel Levesque-TremblayThe epigenome is composed of modifications to DNA that determine which genes of the genome are expressed or suppressed without changing the DNA sequence.
Influence of Epigenetics on Bioprocessing September2018SBE Special SectionMark BlennerHarnessing and applying epigenetics in bioprocessing systems may improve cell line development, productivity, and product quality.
Single-Cell Epigenomic Technology and Applications September2018SBE Special SectionChongli Yuan, Li Lin, Ana Carneiro, Junkai XieThis article highlights developments in single-cell epigenomic monitoring and modulating tools, as well as advances in synthetic epigenetic circuits. These tools are used in important biomedical and industrial applications.
The Untapped Information of the Epigenome September2018SBE Special SectionAlbert J. KeungThe complexity of the epigenome suggests a wealth of untapped biological information and regulatory potential that could be game changing for cellular engineering and biomedical interventions.
Unlocking Access to DNA in Chromatin September2018SBE Special SectionCassandra M. Barrett, Karmella A. HaynesScientists must learn how to open and manipulate chromatin to gain complete access to eukaryotic DNA for genome engineering.
CEP: News Update August2018News UpdateNew CRISPR Findings Raise Concerns Before Technology’s Clinical Debut A pair of studies that investigated the effect of CRISPR-Cas 9 on a key protein that regulates cell growth and protects against cancer has sent shockwaves through the growing...
Technical Entity Trends: CRISPR: Editing Genes One Sequence at a Time June2018Technical Entity TrendsKeith JosephThe technology known as CRISPR — clustered regularly interspaced short palindromic repeats — has taken the field of synthetic bioengineering by storm. It emerged as a gene-editing tool only five years ago, but has become a familiar presence in the lab.
First Complete Human Genome within Sight March 20, 2018Researchers announced this week that they are closing in on producing the first complete and accurate linear map of a human Y chromosome centromere.
CEP: News Update March2018News UpdateVaccine Boosts Immune System Response to Cancer Cancer can be difficult to treat because its highly proliferative cells spread throughout the body, effectively evading the immune system’s surveillance. One opportunity that scientists are pursuing...
Your Experiences Leave a Mark February 13, 2018Epigenetics — the study of how our actions and experiences mark or modify our DNA — can explain some unusual genetic findings.
CEP: News Update January2018News UpdateNew Technique 3D Prints Living Materials Although most 3D printers produce objects from inorganic matter, an international team of scientists has developed a way for their prints to take on a life of their own. Engineers Put Two-Dimensional...