Metabolic Engineering 12

Systems Metabolic Engineering for Superior Bio-Production
June 24-28, 2018
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The Metabolic Engineering Conference is the world-leading conference to share premium developments and achievements in the field. The theme of this year's conference is systems metabolic engineering for superior bio-production.  The conference is chaired by Christoph Wittmann and Oskar Zelder.

The Metabolic Engineering Conference is the world-leading conference to share premium developments and achievements in the field. The theme of this year's conference is systems metabolic engineering for superior bio-production.

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Call for Posters is open.

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Conference Chairs:

  • Christoph Wittmann, Saarland University
  • Oskar Zelder, BASF


  • Hal Alper, University of Texas, Austin
  • Roel Bovenberg, DSM
  • Akihiko Kondo, Kobe University
  • Uwe Sauer, ETH Zurich
  • Hiroshi Shimizu, Osaka University
  • Christina Smolke, Stanford University

Plenary Speakers:

  • Frances Arnold, Caltech
  • Martin Brudermüller, BASF

Keynote Speakers:

Session 1: Systems biology and multi omics insights: Jens Nielsen, Chalmers University
Session 2: Synthetic biology and genome editing: Jay Keasling, UC Berkley
Session 3: Metabolic engineering and adaptive evolution: Jack Pronk, TU Delft
Session 4: Design and assembly of metabolic pathways: Tobias Erb, MPI Marburg
Session 5: Metabolic engineering of microoganisms:  Kristala Prather, MIT
Session 6: Metabolic engineering of higher eukaryotic cells: Martin Fussenegger, ETH Zurich
Session 7: From lab to industry - high value molecules: Christina Smolke,  Stanford University
Session 8: From lab to industry - big volume chemicals: Sang-Yup Lee, KAIST
Session 9: On the horizon: Greg Stephanopoulos, MIT
Workshop I: Modelling: Costas Maranas, Pennsylvania State University
Workshop II: Tools for Commercial Bioprocess Design, Economic Analysis, and Scale-up: Nelson Barton, Genomatica

Featured Speakers

Frances Hamilton Arnold

Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at Caltech, where her research focuses on protein engineering by directed evolution, with applications in alternative energy, chemicals, and medicine. Dr. Arnold pioneered the ‘directed evolution’ of proteins, mimicking Darwinian evolution in the laboratory to create new biological molecules. Her laboratory has developed protein evolution methods that are used widely in industry and basic science to engineer proteins with new and useful properties. Read more

Nelson Barton

Nelson has served as Genomatica’s Senior Vice President of Research and Development since October 2015, after joining in October 2011 as Vice President of Research and Development. Nelson leads R&D from ideation through technology transfer as well as continuing to advance the company’s technology platform and has helped commercialize biobased versions of two major chemicals, 1,4-butanediol and 1,3-butylene glycol. From 2000 to 2011, Nelson held several roles at Verenium Corporation (formerly Diversa Corporation), including Vice President, R&D from 2008 to 2009, Sr. Vice President,...Read more

Martin Brudermüller

Martin Brudermüller is Vice Chairman of the Board of Executive Directors of
BASF SE, a position he assumed in May 2011. He is currently responsible for
the divisions Petrochemicals, Monomers, Intermediates, Process Research
& Chemical Engineering, Innovation Management, Digitalization in
Research & Development, BASF New Business, as well as Corporate
Technology & Operational Excellence.In addition, he is,since May 2015, Chief Technology Officer (CTO). Brudermüller has been a member of the Board of Executive Directors...Read more

Tobias J. Erb

Tobias J. Erb is a Scientific Member of the Max Planck Society and Director at the Max Planck Institute for terrestrial Microbiology in Marburg, Germany. His research interests are the microbial carbon cycle, in particular the biochemistry and synthetic biology of carbon dioxide conversion. Tobi Erb's studies center on the discovery, the function and the design of novel CO2 converting enzymes from bacteria, algae and plants and their use in artificial photosynthesis, as well as the bottom-up design of complex metabolic networks and artificial cells.

Tobi Erb studied...Read more

Martin Fussenegger

Martin Fussenegger is Professor of Biotechnology and Bioengineering at the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel as well as at the University of Basel. His research focuses on mammalian cell engineering, in particular on the assembly of synthetic gene circuits that process complex control and closed-loop expression logic and on the production of theranostic designer cells implants that interface with host metabolism and have the potential to correct prominent metabolic disorders. Martin Fussenegger graduated with Werner Arber at the Biocenter...Read more

Jay Keasling

Jay Keasling is the Hubbard Howe Jr. Distinguished Professor of Biochemical Engineering at the University of California, Berkeley, senior faculty scientist at Lawrence Berkeley National Laboratory, and Chief Executive Officer of the Joint BioEnergy Institute (JBEI). His research focuses on the metabolic engineering of microorganisms for degradation of environmental contaminants or for environmentally friendly synthesis of drugs, chemicals, and fuels.Read more

Sang Yup Lee

Dr. Sang Yup Lee is Distinguished Professor at the Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST). He is currently the Director of Center for Systems and Synthetic Biotechnology, Director of BioProcess Engineering Research Center, and Director of Bioinformatics Research Center.Read more

Costas Maranas

Dr. Costas D. Maranas (b. 1967) is the Donald B. Broughton Professor in the Department of Chemical Engineering at The Pennsylvania State University. The C. Maranas group develops and deploys computational framework informed by systems engineering and mathematical optimization to understand, analyze and redesign metabolism and proteins.Read more

Jens Nielsen

In 2008, Jens Nielsen was recruited as Professor and Director to Chalmers University of Technology, Sweden, where he is currently directing a research group of more than 50 people. At Chalmers he established the Area of Advance Life Science Engineering, a cross departmental strategic research initiative and was founding Head of the Department of Biology and Biological Engineering, which now encompass more than 170 people.Read more

Kristala Jones Prather

Kristala Jones Prather is the Arthur D. Little Professor of Chemical Engineering at MIT. She received an S.B. degree from MIT in 1994 and Ph.D. from the University of California, Berkeley (1999), and worked 4 years in BioProcess Research and Development at the Merck Research Labs prior to joining the faculty of MIT. Her research interests are centered on the design and assembly of recombinant microorganisms for the production of small molecules, with additional efforts in novel bioprocess design approaches. Prather is the recipient of an Office of Naval Research Young Investigator Award (...Read more

Jack Pronk

Dr. Jack Pronk is a Professor of Biotechnology and Microbiology at Delft Technical Universityin the Netherlands. He is a principal investigator in the TU Delft's Industrial Microbiology section (IMB), where he works in the research areas of microbial physiology, microbial performance in industrial contexts and metabolic engineering with, currently, a research focus on yeasts. His specialization is microbial physiology, in which he tries to quantify, understand and improve microbial performance by cultivation and analysis of wild-type and engineered micro-organisms under controlled...Read more

Christina Smolke

Professor Smolke's research program focuses on developing modular genetic platforms for programming information processing and control functions in living systems, resulting in transformative technologies for engineering, manipulating, and probing biological systems. She has pioneered the design and application of a broad class of RNA molecules, called RNA devices, that process and transmit user-specified input signals to targeted protein outputs, thereby linking molecular computation to gene expression. This technology has been extended to efficiently construct multi-input devices...Read more

Gregory Stephanopoulos

Greg Stephanopoulos is presently the W.H. Dow Professor of Chemical Engineering and Biotechnology at MIT, and Instructor of Bioengineering at Harvard Medical School (1997-). He received his BS from the National Technical University of Athens, MS degree from the U. of Florida and PhD from the U. of Minnesota, all in Chemical Engineering. He taught at Caltech between 1978-85, after which he was appointed Professor of ChE at MIT. His current research focuses on metabolic engineering, the engineering of microbes for the production of fuels and chemicals. He has co-authored or –edited 5 books,...Read more