2021 James E. Bailey Award Lecture
James J. Collins, Termeer Professor of Medical Engineering and Science, Massachusetts Institute of Technology, delivered 2021's lecture, Synthetic Biology: Life Redesigned.
Synthetic Biology: Life Redesigned
Synthetic biology is bringing together engineers, physicists and biologists to model, design and construct biological circuits out of proteins, genes and other bits of DNA, and to use these circuits to rewire and reprogram organisms. These re-engineered organisms are going to change our lives in the coming years, leading to cheaper drugs, rapid diagnostic tests, and synthetic probiotics to treat infections and a range of complex diseases. In this talk, we highlight recent efforts to create synthetic gene networks and programmable cells, and discuss a variety of synthetic biology applications in biotechnology and biomedicine.
2021 D.I.C. Wang Award Lecture
William E. Bentley, Robert E. Fischell Distinguished Chair of Engineering, Director of the Robert E. Fischell Institute for Biomedical Devices, Director, Maryland Technology Enterprise Institute and Professor, Institute for Bioscience and Biotechnology Research, Fischell Department of Bioengineering, University of Maryland, delivered the 2021 Lecture.
Exploiting Redox for Connecting Biology to Electronics – Controlling Behavior via Electrogenetics
The Internet of Things has been a truly transformative reality - of great successes, opportunities and challenges. Big data and electronic information transfer, however, typically stops at the interface with biology, it’s aqueous nature largely devoid of free electron transfer. By recognizing that biological redox active molecules are a biological equivalent of an electron-carrying wire, we have developed biological surrogates for electronic devices, including a biological redox capacitor that enable bi-directional “electron” flow. We have also turned to synthetic biology to provide a means to sample, interpret and report on biological information contained in molecular communications circuitry.