CEP: October 2017

The discipline of biomolecular engineering focuses on the interface between molecular biology, biophysical chemistry, and chemical engineering — with the goal to translate our fundamental understanding of molecular biology into useful therapies, devices, and processes. The topics covered in this months special section convey the breadth and depth of emerging areas of biomolecular engineering. Other topics in this issue include steam traps, wireless instrumentation, and respiratory protection.

Editorial

Imagine my excitement when I saw the cover of the latest Reader’s Digest; it was the Genius issue — boasting “Secrets to a sharper mind” and “Why it pays to increase your word power.” I couldn’t wait to dig in! I’m a long-time subscriber — I started reading my parents’ copies when I was in elementary school — and I have always enjoyed the monthly vocabulary quizzes. And now, here was an entire issue with words as its theme. How exciting!

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The Many Applications of Biomolecular Engineering

October
2017
SBE Special Section
Gabriel Levesque-Tremblay
The discipline of biomolecular engineering focuses on the interface between molecular biology, biophysical chemistry, and chemical engineering — with the goal to translate our fundamental understanding of molecular biology into useful therapies, devices, and processes. Applications of this discipline include clinical medicine and developmental biology.

A Materials Approach to Vaccines as Therapies

October
2017
SBE Special Section
Neil Dold, Christopher M. Jewell
The widespread adoption of vaccines over the last two centuries has transformed medicine by preventing infectious disease. In the future, so-called therapeutic vaccines could be used as effective treatments for cancer and autoimmune disorders — ushering in a new era of medicine.

Engineering Cancer-Fighting T Cells

October
2017
SBE Special Section
Eugenia Zah, Yvonne Y. Chen
Adoptive T-cell therapy is a personalized cancer treatment that has the potential to cure previously untreatable malignancies. Researchers are applying techniques in biomolecular engineering and synthetic biology to the development of next-generation therapeutic T cells with improved safety and efficacy against a variety of cancers.

There’s Plenty of Room at the Bottom of a Cell

October
2017
SBE Special Section
Angela R. Wu, Lei Yu
Single-cell RNA sequencing is giving engineers and scientists the ability to better understand and manipulate the smallest unit of a living organism — the single cell. This technique has already ushered in breakthroughs in biology and medicine. However, challenges and opportunities abound.

Computational Protein Engineering

October
2017
SBE Special Section
Robert Pantazes
Proteins could transform the chemical process industries if they could be engineered to facilitate the production of biofuels, molecular medicines, and other specialty chemicals. This reality is nearing as expanded knowledge of proteins and improvements in computational tools are making it possible to design specific protein structures and functions.

SBE Special Section: Biomolecular Engineering (full 34-page section)

October
2017
SBE Special Section
SBE Update: The Many Applications of Biomolecular Engineering; A Materials Approach to Vaccines as Therapies; Engineering Cancer-Fighting T Cells; There's Plenty of Room at the Botton of a Cell; Computational Protein Engineering; Plant Metabolic Engineering for Chemicals, Fuels, and Precursors

Go Wireless

October
2017
Instrumentation
Dale Perry
Wireless adapters help plants acquire stranded data from HART-enabled instrumentation to reduce operator rounds, prevent overfill, track inventory, and more.

10 Steps to Protect Workers against Airborne Hazards

October
2017
Safety
Erik W. Johnson
Respiratory safety involves more than properly wearing and maintaining personal protective equipment (PPE). Follow these steps to evaluate hazards and establish effective procedures to mitigate those hazards.
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