Technical Program
Technical Program for 2024 mSBW
To learn more about the abstracts please CLICK HERE
| Day 1 | ||
| Start Time | End Time | |
| 8:00 AM | 4:00 PM | Registration |
| 9:00 AM | 9:15 AM | Welcome Remarks by Chairs: Katie Galloway, MIT and John Ngo, Boston University |
| 9:15 AM | 10:00 AM | Keynote Speaker: Synthetic Biology: Making Biology Programmable, Jim Collins, MIT |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:00 PM | Session 1: Scalable Technologies and Artificial Intelligence Session Chair: John Ngo |
| 10:30 AM | 11:00 AM | Invited Speaker: A Scalable Biology Approach to Rationally Engineer Drugs for Cellular Mechanisms, Naomi Handly, Octant Bio |
| 11:00 AM | 11:30 AM | Invited Speaker: Integrating synthetic biology, computer-aided design, and AI models to advance therapeutics manufacturing, Alec Nielsen, Asimov |
| 11:30 AM | 11:45 AM | Selected Abstract: Generalizable Design of Human Cell Type-Specific Expression Via Deep Learning Models of Genomic Accessibility, Sebastian M. Castillo-Hair, University of Washington |
| 11:45 AM | 12:00 PM | Selected Abstract: Reconstructing Signaling History and Spatial Organization of Single Cells with Generalizable Statistical Inference, Nicholas Hutchins, MIT |
| 12:00 PM | 1:00 PM | Lunch |
| 1:00 PM | 1:45 PM | Keynote Speaker: RNA and RNP Synthetic Biology to Program Cells, Hirohide Saito, Kyoto University |
| 1:45 PM | 3:00 PM | Session 2: Synthetic Biology for Therapeutics Session Chair: Kyle Daniels |
| 1:45 PM | 2:15 PM | Invited Speaker: Remote Control of Genetics/Epigenetics and Cellular Functions for Cancer Immunotherapy, Peter Wang, USC |
| 2:15 PM | 2:30 PM | Selected Abstract: Piggybac Transposon Bioprospecting Enables Discovery of Hyperactive Variants for Precise Gene Writing, Dimitrije Ivančić, UPF/ITX |
| 2:30 PM | 2:45 PM | Selected Abstract: A Single-Transcript, microRNA-Based Incoherent Feedforward Loop Delivers Precise Transgene Expression in Primary Cells, Kasey Love, MIT |
| 2:45 PM | 3:00 PM | Selected Abstract: Synziftr 2.0: Development of Novel Transcriptional Activation Domain Architectures for Clinically-Optimized Gene Circuit Engineering, Hanrong Ye, Boston University |
| 3:00 PM | 3:10 PM | Funding Landscape and Opportunities at the NIH, Nichole Daringer, NIH/NIBIB |
| 3:10 PM | 4:40 PM | Poster Session 1 with Afternoon Coffee Break |
| 4:40 PM | 6:10 PM | Session 3: Foundational Technologies Session Chair: Caleb Bashor |
| 4:40 PM | 5:10 PM | Invited Speaker: Pooled screening to optimize therapeutic design, Shawdee Eshghi, Ginkgo Bioworks |
| 5:10 PM | 5:40 PM | Invited Speaker: A systems and synthetic biology approach to probing multicellular stem cell dynamics, Nika Shakiba, UBC |
| 5:40 PM | 5:55 PM | Selected Abstract: FAST-STEM: A Human Pluripotent Stem Cell Engineering Toolkit for Rapid Design-Build-Test-Learn Development of Human Cell-Based Therapeutic Devices, Aaron Rosenstein, University of Toronto |
| 5:55 PM | 6:10 PM | Selected Abstract: Engineering Programmable RNA Condensates in Mammalian Cells, Shiyi Li, UCLA |
| Day 2 | ||
| Start Time | End Time | |
| 8:00 AM | 4:00 PM | Registration |
| 9:00 AM | 9:15 AM | Day 2 Welcome Remarks by Chairs |
| 9:15 AM | 10:00 AM | Keynote Speaker: The Many Life Cycles Of RNA, Stirling Churchman, Harvard Medical School |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:00 PM | Session 4: Synthetic Gene Regulation Approaches Session Chairs: Katie Galloway |
| 10:30 AM | 11:00 AM | Invited Speaker: Synthetic and precise control over endogenous gene expression using designer RNAs and engineered human proteins Isaac Hilton, Rice University |
| 11:00 AM | 11:30 AM | Invited Speaker: Scalable access to hidden topologies of biological networks, Albert Keung, NC State |
| 11:30 AM | 11:45 AM | Selected Abstract: Drug-Inducible RNA Alternative Splicing As Synthetic Switches for RNA and Protein Biogenesis, Yu Zhou, University of Florida |
| 11:45 AM | 12:00 PM | Selected Abstract: Robust and Tunable Proteolytic Feedforward Dosage Control, Noa Katz, Stanford University |
| 12:00 PM | 1:00 PM | Lunch |
| 1:00 PM | 1:45 PM | Keynote Speaker: Christopher Chen, Boston University |
| 1:45 PM | 3:15 PM | Session 5: Developmental, Multicellular, and Regenerative Systems Session Chair: Leonardo Morsut |
| 1:45 PM | 2:15 PM | Invited Speaker: Synthetic gene circuits for decoding and controlling stem cell self-organization, Jared Toettcher, Princeton University |
| 2:15 PM | 2:45 PM | Invited Speaker: Interrogating and manipulating neuromuscular biology with light, Ritu Raman, MIT |
| 2:45 PM | 3:00 PM | Selected Abstract: Straight-in v3.0: An Improved Platform for Dual Targeted Integrations of Large DNA Payloads into Human Pluripotent Stem Cells, Albert Blanch Asensio, Leiden University Medical Center |
| 3:00 PM | 3:15 PM | Selected Abstract: Anthrobots: Leveraging Anatomical Tissue Plasticity for Synthetic Morphogenesis, Gizem Gumuskaya, Tufts University & Harvard University |
| 3:15 PM | 4:45 PM | Poster Session 2 with Afternoon Coffee Break |
| 4:45 PM | 6:15 PM | Session 6: Synthetic Biology for Cancer Session Chair: Tara Deans |
| 4:45 PM | 5:15 PM | Invited Speaker: Engineered bacteria for cancer therapy, Tal Danino, Columbia University |
| 5:15 PM | 5:45 PM | Invited Speaker: Enzymatic control of protocell systems: autonomous motility and condensate design, Dan Hammer, University of Pennsylvania |
| 5:45 PM | 6:00 PM | Selected Abstract: Engineering a Multimodal Vaccination Strategy for Cold Tumors Using Multi-Input miRNA Classifier Circuits Encoded on Self-Amplifying RNA, Fabio Caliendo, Massachusetts Institute of Technology |
| 6:00 PM | 6:15 PM | Selected Abstract: Targeted Depletion and Inhibition of GPCRs in Cancer Via Induced Proximity, Kaitlin Rhee, Dana-Farber Cancer Institute/Harvard Medical School |
| 6:15 PM | 6:30 PM | Closing Remarks by Chairs: Katie Galloway, MIT and John Ngo, Boston University |
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