Technical Program | AIChE

Technical Program

Program is subject to change. Last updated 1/4. ...

Program is subject to change. Last updated 1/4.


Eastern Standard Time Wednesday, January 6
9:50 AM - 10:00 AM  Welcome Remarks
10:00 AM - 10:35 AM Keynote Speaker: A colorful solution to 'breathing' through a biofilm

Dianne Newman, California Institute of Technology
10:35 AM - 10:40 AM Stretch Break and Hallway Chats
10:40 AM - 12:05 PM Session 1: Synthetic Biology

Session Chair: Mattheos Koffas, RPI
10:40 AM - 11:00 AM Invited Speaker: Writing the Future of Synthetic Biology

Emily Leproust, Twist Biosciences
11:00 AM - 11:20 AM Invited Speaker: ENGINEERING A COMPLEX PHENOTYPE: A MULTI-FACETED APPROACH TO CREATING A NEW PROTEIN BIOMANUFACTURING PLATFORM

Danielle Tullman-Ercek, Northwestern University
11:20 AM - 11:35 AM A Toxin-Triggered Vehicle for Targeted Delivery of Antibiotics

Angela Brown, Lehigh University
11:35 AM - 11:50 AM  Metabolic Regulation and Engineering in the Basidiomycete Red Yeast Xanthophyllomyces Dendrorhous

Eric Young, Worcester Polytechnic Institute
11:50 AM - 12:05 PM  A Plug-and-Play RNA Detection Platform for Sensing Cell Physiology and Phenotype

James Chappell, Rice University
12:05 PM - 12:10 PM Stretch Break and Hallway Chats
12:10 PM - 1:35 PM Session 2: Protein Engineering

Session Chair: Ian Wheeldon, UC Riverside
12:10 PM - 12:30 PM Invited Speaker: Emerging strategies for performing drug discovery on the yeast surface

James Van Deventer, Tufts University
12:30 PM - 12:50 PM Invited Speaker: G-protein coupled receptors: Chimeras improve surface localization without loss of native protein-protein interactions

Anne Skaja Robinson, Carnegie Mellon University
12:50 PM - 1:05 PM Deep Mutagenesis-Guided Engineering of Soluble Decoy Receptors for Targeting Viral Diseases

Erik Procko, University of Illinois at Urbana-Champaign
1:05 PM - 1:20 PM Genetic and Structural Convergence of Protective Plasma IgG Antibodies That Target the N-Terminal Domain of the Sars-Cov-2 Spike Glycoprotein

Gregory Ippolito, University of Texas at Austin
1:20 PM - 1:35 PM Predicting Antibody Developability

Peter Tessier, University of Michigan-Ann Arbor
1:35 PM - 2:00 PM Networking Break
   
Eastern Standard Time Thursday, January 7
10:00 AM - 10:35 AM Keynote Speaker: Occam’s Pharmacokinetics:  Intratumoral Administration and Retention of Immune Agonists

Dane Wittrup, Massachusetts Institute of Technology
10:35 AM - 10:40 AM Stretch Break and Hallway Chats
10:40 AM - 12:05 PM Session 3: Computational & Experimental Tools for Biological Systems

Session Chair: Jerzy Szablowski, Rice University
10:40 AM - 11:00 AM Invited Speaker: Simultaneous quantification of the epigenome and transcriptome in single cells

Siddharth Dey, University of California, Santa Barbara
11:00 AM - 11:20 AM Invited Speaker: Systems engineering approaches to advance understanding of cell migration

Stephanie Fraley, University of California, San Diego
11:20 AM - 11:35 AM Computational Redesign of Bacterial Chondroitinase ABC to Treat Spinal Cord Injury and Stroke

Matthew O'Meara, University of Michigan
11:35 AM - 11:50 AM  Developing a Mechanistic View of Mixed IgG Antibody Immune Effector Responses

Aaron Meyer, University of California, Los Angeles
11:50 AM - 12:05 PM  The Structural Basis for Protein Energy Landscapes in a De Novo Designed Proteome

Gabriel Rocklin, Northwestern University
12:05 PM - 12:10 PM Stretch Break and Hallway Chats
12:10 PM - 1:35 PM Session 4: Nanoscale Platforms for Biological Design

Session Chair: Javin Oza, CalPoly San Luis Obispo
12:10 PM - 12:30 PM Invited Speaker: How multispecific drugs are transforming Amgen’s pipeline

Ray Deshaies, Amgen
12:30 PM - 12:45 PM Redox Balance-Based Growth Selection As a Universal Tool for Enzyme Engineering

Han Li, University of California, Irvine
12:45 PM - 1:00 PM Tandem Membrane Protein Cryo-EM and Assays in Dynamically Loadable and Intact Lipid Bilayers

M. Lane Gilchrist, City College of New York
1:00 PM - 1:15 PM Discovery and Design of Protein Developability

Benjamin Hackel, University of Minnesota
1:15 PM - 2:00 PM Networking Break
   
Eastern Standard Time Friday, January 8
10:00 AM - 10:35 AM Keynote Speaker: Biomimetic Patterning to Control and Manipulate Cell Behaviors

Jennifer West, Duke University
10:35 AM - 10:40 AM Stretch Break and Hallway Chats
10:40 AM - 11:50 AM Session 5: Cellular Engineering

Session Chair: Jamie Spangler, Johns Hopkins University
10:40 AM - 11:00 AM Invited Speaker: Engineering Next-Generation T Cells for Cancer Immunotherapy

Yvonne Chen, University of California, Los Angeles
11:00 AM - 11:20 AM Invited Speaker: Synthetic Mechanobiology: Engineering How Cells Sense and Interpret Mechanical Cues

John Ngo, Boston University
11:20 AM - 11:35 AM Engineering Inhibitory Proteins to Augment Cancer Immunotherapy

Lawrence Stern, University of South Florida
11:35 AM - 11:50 AM  CRISPR-Mediated Engineering of Photoautotrophs to Improve Biomass Productivity

Anne Ruffing, Sandia National Labs
11:50 AM - 12:05 PM Stretch Break and Hallway Chats
12:05 PM - 1:15 PM Session 6: Biomaterials Engineering

Session Chair: April Kloxin, University of Delaware
12:05 PM - 12:25 PM Invited Speaker: A Synthetic Platform for the Design and Quantification of Multifunctional Antibody Drug Carriers

Chris Alabi, Cornell University
12:25 PM - 12:45 PM Invited Speaker: Bioinspired Elastin-based Adhesives

Julie Liu, Purdue University
12:45 PM - 1:00 PM Leveraging Natural Protein-Material Interactions to Control the Delivery of Bone Morphogenetic Protein-2 for Bone Repair

Marian Hettiaratchi, University of Oregon
1:00 PM - 1:15 PM Programmable Nucleation and Self-Assembly of Artificial Virus-like Particles Guided By CRISPR-Cas12a

Armando Hernandez-Garcia, Universidad Nacional Autonoma de Mexico
1:15 PM - 2:00 PM Poster Session + Lightning Talks
   
Eastern Standard Time Saturday, January 9
10:00 AM - 10:35 AM Keynote Speaker: Normalizing the Tumor Microenvironment to Improve Cancer Treatment: From Math Modeling to Mice to Patients and Back

Rakesh Jain, Harvard University
10:35 AM - 10:40 AM Stretch Break and Hallway Chats
10:40 AM - 12:05 PM Session 7: Molecular Medicine

Session Chair: Julie Champion, Georgia Tech
10:40 AM - 11:00 AM Invited Speaker: High-throughput T cell repertoire profiling enabled systems immunology and immune engineering

Jenny Jiang, University of Texas at Austin
11:00 AM - 11:20 AM Invited Speaker: Using Synthetic Biology to Improve Cell Therapies

Tara Deans, University of Utah
11:20 AM - 11:35 AM Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products

Jerome Fox, University of Colorado Boulder
11:35 AM - 11:50 AM  Towards Improved Safety and Efficacy of Live Bacterial Vaccines Using an Expanded Genetic Code

Aditya Kunjapur, University of Delaware
11:50 AM - 12:05 PM  An Engineered Enzyme to Help the Immune System Fight Cancer: From Proof of Concept to Clinical Translation

John Blazeck, Georgia Tech.
12:05 PM - 12:10 PM Stretch Break and Hallway Chats
12:10 PM - 1:35 PM Session 8: Emerging Technologies in Molecular Engineering

Session Chair: Arnab Mukherjee, University of California, Santa Barbara
12:10 PM - 12:30 PM Invited Speaker: Measuring signaling dynamics without live-cell microscopy

Jared Toettcher, Princeton University
12:30 PM - 12:50 PM Invited Speaker: Watching the brain in action: creating tools for functional analysis of neural circuitry

Lin Tian, UC Davis
12:50 PM - 1:05 PM Biased Activation of the MHC-I:PD-L1 Axis Via Engineered Interferon Gamma Partial Agonists

Juan Mendoza, University of Chicago
1:05 PM - 1:20 PM Temperature-Responsive Optogenetic Probes of Ras and PI3K Signaling

Lukasz Bugaj, University of Pennsylvania
1:20 PM - 1:35 PM Multi-Tasking Tags for Correlated Light and Electron Microscopy

Kimberly Beatty, Oregon Health & Science University
1:35 PM - 1:40 PM Closing Remarks