Technical Program
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| Start Time | End Time | |
| November 15, 2023 | All Central Standard Time | |
| Day 1 | ||
| 8:00 AM | 4:00 PM | Registration |
| 9:00 AM | 9:10 AM | Welcome Remarks by Chairs |
| 9:10 AM | 10:00 AM | KEYNOTE: Stepping on the Gas Towards a Circular Economy – Cell-Free Synthetic Biology to Accelerate Biomanufacturing from Waste Gases, Michael Koepke, LanzaTech |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 11:15 AM | Deploying Cell Free Systems in the Real World (Session Chair: Khalid) |
| 10:30 AM | 11:00 AM | Invited Speaker: Strategies and Considerations Toward Scaling up Cell-Free ProteinExpression to Kiloliters Scale, Ee-Been Goh, SutroBio |
| 11:00 AM | 11:15 AM | Selected Abstract: Point-of-Need Cell Free Lysate-Based Sensor Integration into Fieldable Devices for Warfighter Protection, Daniel Phillips, U.S. Army DEVCOM Chemical Biological Center |
| 11:15 AM | 11:30 AM | Pick up Boxed Lunch |
| 11:30 AM | 12:30 PM | Lunch Workshop Panel Chaired by Weston Kightlinger and David Tennenhouse; Panelists: Kate Adamala, Karen Polizzi, James Zawada, and Michael Koepke |
| 12:30 PM | 12:45 PM | Bathroom Break |
| 12:45 PM | 2:15 PM | Cell Free Metabolic Engineering (Session Chair: Karen and Paul) |
| 12:45 PM | 1:15 PM | Invited Speaker: Cell-Free Machine Learning-Guided Protein Engineering Unlocks the ‘Biocatalytic Potential’ of Enzymes, Ashty Karim |
| 1:15 PM | 1:45 PM | Invited Speaker: Quentin Dudley |
| 1:45 PM | 2:00 PM | Selected Abstract : A Self-Regenerating Metabolic and Genetic Linked in Vitro Network, Simone Giaveri, Max Planck Institute for Terrestrial Microbiology |
| 2:00 PM | 2:15 PM | Selected Abstract : Spyphage: A Cell Free Transcription/Translation Platform for Rapid Engineering of Targeted Phage Therapies., Sahan Liyanagedera, University of Edinburgh |
| 2:15 PM | 2:45 PM | Afternoon Coffee Break |
| 2:45 PM | 3:45 PM | Cell Free Biomanufacturing (Session Chairs: Weston, Zach) |
| 2:45 PM | 3:15 PM | Invited Speaker: Towards Carbon Negative Chemicals with Cell-free Biomanufacturing, Bastian Vogeli, Invizyne Technologies |
| 3:15 PM | 3:30 PM | Selected Abstract: Accelerating Drug Development Using Cell-Free Protein Synthesis, Jeffrey Hanson, Sutro Biopharma |
| 3:30 PM | 3:45 PM | Selected Abstract: Scaling Cell-Free Expression (CFE) Systems As a Tool for Biomanufacturing, Katherine Rhea, US Army DEVCOM Chemical Biological Center |
| 3:45 PM | 4:45 PM | Poster Session 1 + Cocktail Reception Sponsored by SutroBio |
| Start Time | End Time | |
| November 16, 2023 | All Central Standard Time | |
| Day 2 | ||
| 8:30 AM | 3:00 PM | Registration |
| 9:00 AM | 9:10 AM | Day 2 Welcome By Chairs |
| 9:10 AM | 10:00 AM | KEYNOTE: The myTXTL system and its utilization for cell-free bioengineering, Vincent Noireaux, University of Minnesota |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 12:00 PM | Bottom Up Cell Free (Session Chairs: Sebastian, Kate) |
| 10:30 AM | 11:00 AM | Invited Speaker: Andrew Ellington |
| 11:00 AM | 11:30 AM | Invited Speaker: Yoshihiro Shimizu |
| 11:30 AM | 11:45 AM | Selected Abstract: Nucleus: an open-source, full-stack distribution that lets you start developing with synthetic cell systems today, Anton Jackson-Smith, b.next |
| 11:45 AM | 12:00 PM | Selected Abstract: Integration and in Vitro Evolution of Autogene Networks Towards Synthetic Life, Zhanar Abil, University of Florida |
| 12:00 PM | 1:00 PM | Lunch |
| 1:00 PM | 2:30 PM | Cell Free Biosensing and Diagnostics (Session Chairs: Khalid, Neha) |
| 1:00 PM | 1:30 PM | Invited Speaker: Detection of heavy metal contamination and biological threats in low-resource environments using cell-free systems, Matthew Lux, U.S. Army DEVCOM Chemical Biological Center |
| 1:30 PM | 2:00 PM | Invited Speaker: Javin Oza |
| 2:00 PM | 2:15 PM | Selected Abstract: Prototyping a Complex Enzyme Cascade Using in Vitro Transcription-Based Biosensing, Sebastian Barthel, Max Planck Institute for Terrestrial Microbiology |
| 2:15 PM | 2:30 PM | Selected Abstract: High-Throughput Optimization of Paper-Based Cell-Free Biosensors, David Garcia, DEVCOM Chemical Biological Center |
| 2:30 PM | 3:00 PM | Afternoon Coffee Break |
| 3:00 PM | 4:15 PM | Cell Free for Rapid Prototyping (Session Chairs: Zach, Gordon) |
| 3:00 PM | 3:30 PM | Invited Speaker: Prototyping cell-free systems for antimicrobials and resistance, Simon Moore, Queen Mary University of London |
| 3:30 PM | 3:45 PM | Invited Speaker: Rapid Process Development for Cell-Free Production of Biopharmaceuticals, Jiahui Xie, SutroBio |
| 3:45 PM | 4:00 PM | Selected Abstract: Synthetic Prototyping of Spider Silk Proteins Using Cell Free Systems, Daniela, Bittencourt, Embrapa Genetic Resources and Biotechn |
| 4:00 PM | 4:15 PM | Selected Abstract: Rapid All-in Vitro Bacteriophage Engineering Using Cell-Free Bacteriophage Synthesis, Rani Brooks, Tulane University |
| Start Time | End Time | |
| November 17, 2023 | All Central Standard Time | |
| Day 3 | ||
| 8:30 AM | 2:00 PM | Registration |
| 9:00 AM | 9:10 AM | Day 2 recap by Chairs |
| 9:10 AM | 10:00 AM | KEYNOTE: James Swartz, Stanford University |
| 10:00 AM | 10:30 AM | Morning Coffee Break |
| 10:30 AM | 11:30 AM | Cell Free Systems for Understanding Biology (Session Chairs: Karen, Sebastian, Dora) |
| 10:30 AM | 11:00 AM | Invited Speaker: Noise Minimization in Cell-Free Gene Expression, Maike Hansen, Radboud University |
| 11:00 AM | 11:30 AM | Invited Speaker: Paula Booth |
| 11:30 AM | 12:30 PM | Lunch |
| 12:30 PM | 1:45 PM | Development, Characterization and Reproducibility of Cell Free Systems Session Chairs: Gordon, Weston) |
| 12:30 PM | 1:00 PM | Invited Speaker: Toward Universally Available, Low-Cost, at-Home Medical Diagnostics with Cell-Free Systems: Efficient Reagent Preparation & Colorimetric Readouts from a Drop of Blood, Brad Bundy, Brigham Young University |
| 1:00 PM | 1:30 PM | Invited Speaker: Novel polyphosphate kinase 2 synthesizes all four nucleotide triphosphates from monophosphates and its application to cell-free systems, Tomoaki Matsuura, Earth-Life Science Institute (ELSI), Tokyo Institute of Technology (Japan) |
| 1:30 PM | 1:45 PM | Selected Abstract: Production and Applications of LTE, a Flexible and Practical Cell-Free System Based on the Eukaryotic Parasite Leishmania Tarentolae, Wayne Johnston, QUT |
| 1:45 PM | 2:00 PM | Closing Remarks by Chairs |
