Technical Program
Saturday October 28th
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Saturday October 28th
| 7:30 AM - 12:00 PM | Registration |
| 8:45 AM - 9:00 AM | Welcome Remarks |
| 9:00 AM - 11:30 AM | Session 1: Stem Cells |
| Chair: Wei Shen, University of Minnesota | |
| 9:00 AM - 9:30 AM | Invited Speaker: "Stem Cell Aging and Reprogramming: Implications for Regenerative Medicine" — Stelios Andreadis, University at Buffalo, SUNY |
| 9:30 AM - 9:45 AM | "Atomistic Simulations for Construction of an “in Vitro - In Vivo - Ex Vivo – in Cyto - in silico” Performance-Correlation Profile within Biomedical Material Assemblies." — Pradeep Kumar, University of the Witwatersrand |
| 9:45 AM - 10:00 AM | "Cortical Spheroid Development Tracked with a Novel Imaging Platform (DNA-PRISM) Reveals Culture Complexity and Establishes Reproducible Phenotype Baseline for Compound Screens and Disease Modeling." Martin L Tomov, Broad Institute, Cambridge |
| 10:00 AM - 10:15 AM | "Engineering the Liver Diverticulum from Human Pluripotent Stem Cells." — Ogechi Ogoke, University at Buffalo, SUNY |
| 10:15 AM - 10:45 AM | Break |
| 10:45 AM - 11:00 AM | "Formation of Adipose Stromal Vascular Fraction Cell Laden Spheroids Using a 3D Bioprinter and Superhydrophobic Surfaces." — Piyani Gandhi, University of Louisville |
| 11:00 AM - 11:15 AM | "Scalable Production of Human Cardiac Tissues through hiPSC Encapsulation in Gelatin Methacryloyl" — Morgan Ellis, Auburn University |
| 11:15 AM - 11:30 AM | "Encapsulation of Mesenchymal Stem Cells in GAG-Chitosan Polyelectrolyte Microcapsules Using a Novel Electrospraying Technique: Investigating Capsule Morphology and Cell Viability." — Amin Vossoughi Shahvari, Wayne State University |
| 11:30 AM - 1:00 PM | Lunch |
| 1:00 PM - 3:15 PM | Session 2: Immunoengineering |
| Chair: Fei Wen, University of Michigan | |
| 1:00 PM - 1:30 PM | Invited Speaker: "Vignettes on Engineering Targeted, Immunomodulatory Therapies"— Michael Look, Pfizer |
| 1:30 PM - 1:45 PM | "Inhibition of Cancer Immune Suppression with a First-in-Class Engineered Therapeutic Enzyme." — John Blazeck ,University of Texas at Austin, Austin |
| 1:45 PM - 2:00 PM | "Engineering Robust T Cells for Cancer Immunotherapy." — Yvonne Y. Chen, University of California, Los Angeles |
| 2:00 PM - 2:15 PM | "Quantitative In Vivo & Ex Vivo Multimodality Cell Imaging of Antigen-Specific T-Cells in Murine Metastatic Ovarian Cancer." — Matthew Willadsen, University at Buffalo, SUNY |
| 2:15 PM - 2:30 PM | "Single-Cell Profiling Demonstrates That Migratory T Cells Demonstrate Superior Persistence and Enhanced Tumor Control." — Navin Varadarajan, University of Houston |
| 2:30 PM - 2:45 PM | "Engineering Nanotechnologies for Immuno-Oncology: "Smart" Nanoparticles for Immunotherapeutic Targeting of the Sting Pathway." — John Wilson, Vanderbilt University |
| 2:45 PM - 3:00 PM | "Direct Selection of Synthetic Binding Proteins That Recognize Post-Translationally Modified Proteins in Living Cells." — Bunyarit Meksiriporn, Cornell University |
| 3:00 PM - 3:15 PM | "Utilizing Oxygen-Inhibited Photopolymerization to Control Size of Multimodal PEGDA Hydrogel Nanoparticles for Cancer Therapeutics."— Daniel Debroy, University of Wyoming |
| 3:15 PM - 3:45 PM | Break |
| 3:45 PM - 6:30 PM | Session 3: Translation (VC, IP, regulatory, business) |
| Chair: Yiannis Kaznessis, University of Minnesota | |
| 3:45 PM - 4:15 PM | Invited Speaker: "3D Printing Functional Materials & Devices for Biomanufacturing." — Michael McAlpine, University of Minnesota |
| 4:15 PM - 4:30 PM | “Accelerated Development Pathways for Biopharmaceuticals – Will Your CMC Package Be Submission Ready?” — Arindam Bose, AbiologicsB, LLC |
| 4:30 PM - 4:45 PM | "Commercial considerations in the development of therapy-enabling technologies" — Paul Burke, Burke Bioventures |
| 4:45 PM - 5:00 PM | "How will the field of gene therapy survive its success?" — Bill Kaemmerer, CGTA Research Group |
| 5:00 PM - 5:15 PM | "Translation of viral and non-viral gene transfer for metabolic disease" — Scott McIvor, University of Minnesota, Discovery Genomics Inc., Immunosoft Corp. |
| 5:15 PM - 5:30 PM | "Translational Research in a University Setting: Too many “local” hurdles and how to avoid them" — Nicholas Peppas, The University of Texas at Austin |
| 5:30 PM - 5:45 PM | "Translating Big Ideas into Novel Therapies…from Science to Entrepreneurial Startups" — John Santini, Vergent Bioscience |
| 5:45 PM - 6:30 PM | Discussion |
| 6:30 PM - 7:30 PM | Poster Session |
Sunday October 29th
| 8:30 AM - 9:30 AM | Registration |
| 9:30 AM - 11:15 AM | Session 4: Biopharmaceuticals |
| Chair: Honggang Cui, Johns Hopkins University | |
| 9:30 AM - 10:00 AM | Invited Speaker:" Role of Folate-Dependent One-Carbon Metabolism and Transulfuration Pathways in Autism Spectrum Disorder"— Juergen Hahn, Rensselaer Polytechnic Institute |
| 10:00 AM - 10:15 AM | "Site-Directed Polymer-Drug Complexes for Modulating Gut Innate Immune System to Prevent/Treat Inflammatory Bowel Diseases (IBD)." — Siddharth Kesharwani, South Dakota State University |
| 10:15 AM - 10:30 AM | "Lipid-Polymer Hybrid Nanoparticles Incorporating Diverse HIV-1 Cure Agents for Latency Reversal." — Shijie Cao. University of Washington |
| 10:30 AM - 10:45 AM | Break |
| 10:45 AM - 11:00 AM | "FRET-Based High-Throughput Screening of Small-Molecule Inhibitors of TNF Receptors." — Chih Hung Lo, University of Minnesota |
| 11:00 AM - 11:15 AM | "Interfacial Curvature Effects on Morphology and Dynamics of Monolayer Membrane." —Amit Kumar Sachan, University of Minnesota |
| 11:15 AM - 11:30 AM | "Microbial Delivery of Antimicrobial Peptides for Protection Against Multidrug-Resistant Pathogens." — Yiannis Kaznessis University of Minnesota |
| 11:30 AM - 1:00 PM | Lunch |
| 1:00 PM - 3:00 PM | Session 5: Gene and Drug Delivery |
| Chair: Katie Whitehead, Carnegie Mellon University | |
| 1:00 PM - 1:30 PM | Invited Speaker: "Systemic, Targeted Nanotherapies for the Treatment of Neuroinflammation in CNS Disorders: From Chemistry to Clinical Translation"— Rangamanujam Kannan, Johns Hopkins University |
| 1:30 PM - 1:45 PM | "Effect of Alkylation on the Cellular Uptake of Polyethylene Glycol-Coated Gold Nanoparticles." — Chung Hang Jonathan Choi, The Chinese University of Hong Kong |
| 1:45 PM - 2:00 PM | "Self-Assembling Prodrugs" — Honggang Cui, Johns Hopkins University |
| 2:00 PM - 2:15 PM | "Enhancing Therapeutic Efficacy of Self-Assembling Prodrugs with Supramolecular Chemistry" — Hao Su, Johns Hopkins University |
| 2:15 PM - 2:30 PM | "Microfluidics: Accelerating Nanomedicine Research and Development" — Andrea Armstead, Precision Nanosystems |
| 2:30 PM - 2:45 PM | "Topical Drug Delivery to Skin Using STAR Particles" — Mark R. Prausnitz Georgia Institute of Technology |
| 2:45 PM - 3:00 PM | "Intracellular and Extracellular Delivery of Protein and Small Biomolecules Via Near-Infrared Light." — JeongEun Shin, University of Minnesota |
| 3:00 PM - 3:30 PM | Break |
| 3:30 PM - 4:45 PM | Session 5: Gene and Drug Delivery Continued |
| Chair: Samira Azarin, University of Minnesota | |
| 3:30 PM - 3:45 PM | "Fine-Tuning the Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels" — Rami Chakroun, Johns Hopkins University |
| 3:45 PM - 4:00 PM | "Metal Ion Triggered Assembly of Peptide-Drug Conjugates" — Han Wang, Johns Hopkins University |
| 4:00 PM - 4:15 PM | "Cartilage Penetrating Nanocarriers to Provide Sustained Delivery of Disease Modifying Drugs in Post-Traumatic Osteoarthritis" — Brett C Geiger Massachusetts Institute of Technoloy |
| 4:15 PM - 4:30 PM | "Investigating the Impact of the Surface Properties of Intravitreally Injected Carriers on Their Retinal Bio-Distribution in a Single Nanoplatform." — Xiaonan Huang The Hong Kong University of Science and Technology |
| 4:30 PM - 4:45 PM | "Rapid, Room-Temperature Nanoparticle Drying and Low Energy Reconstitution Via Electrospinning." — Shani Levit, Virginia Commonwealth University |
| 4:45 PM - 5:00 PM | Closing Remarks |
