Workshop: Tools for Commercial Bioprocess Design and Economic Analysis | AIChE

Workshop: Tools for Commercial Bioprocess Design and Economic Analysis

  • Thursday, June 19 - PDT

  • The purpose of this workshop is to share strategies and tools for commercial bioprocess design and economic analysis.  Sef Heijnen will describe, with modest information, how to visualize the outcome – a full scale fermentation process – and the fundamental importance of doing so before a research program is started in order to deliver production microbes that scale successfully.  Jeff Lievense and Alex Patist will provide a set of tools for deriving full scale plant capital and production costs given basic information on the product, biochemical stoichiometries, feedstocks, product recovery approach, plant size and location.  A quantitative dashboard will be introduced as a means of tracking process development progress and its competitiveness.  Three case studies will be presented during the workshop.


    8:00-11:00 AM Workshop- Tools for Commercial Bioprocess Design and Economic Analysis
    8:00-8:05 AM Introduction- Jeff Lievense, Genomatica
    8:05-8:40 AM Reverse the Direction in Bioprocess Development: From Full Scale to Synthetic Biology- Sef Heijnen, TU Delft
    8:40-9:40 AM Economic Analysis of Fermentation Processes (Feedstock, Capital, Production Costs) - Jeff Lievense and Alex Patist, Genomatica
    9:40-9:50 AM Break
    9:50-10:10 AM Engineering Cost Model - Alex Patist
    10:10-10:40 AM Case Studies (3-hydroxypropionic acid, undecanoic acid) - Jeff Lievense and Alex Patist
    10:40-10:55 AM                  Process Omics: Chemical Advantage Dashboard - Jeff Lievense
    10:55-11:00 AM Closing Remarks - Alex Patist