Genome Scale Engineering | AIChE

Genome Scale Engineering

This session will focus on the simultaneous engineering of multiple aspects of the genome; including metabolic pathways as well as off pathway modifications that might enhance flux, increase tolerance, alter redox metabolism, among other traits relevant to metabolic engineering. It is anticipated that this session will focus more on basic technology development, although applications will be welcome. 

Session Chairs

  • Hal Alper, University of Texas at Austin
  • Zach Serber, Zymergen


  • Comprehensive characterization of genotype to phenotype relationships in E.coli- Morten Sommer, Technical University of Denmark
  • Metabolic Engineering via RNAi-Assisted Genome Evolution (RAGE)- Huimin Zhao, University of Illinois
  • Genetically Encoded Biosensors + FACS + Recombineering: Versatile Tools for Strain and Enzyme Development- Michael Bott, Forschungzentrum Juelich
  • A Unique Bioengineering Platform for the Efficient Optimization of Metabolic Pathways- Kedar Patel, DNA2.0 Inc.
  • Flux Response of Glycolysis and Storage Metabolism during Rapid Feast/Famine Conditions in Penicillium Chrysogenum Using Dynamic 13C Labeling- S. Ajosch Wahl, DUT, Kluyver Netherlands