Share *Please note this schedule is subject to change. Check back frequently for updates. Last updated: 7.10.19.Thursday, September 12 7:30 AM - 12:00 PM Registration 9:00 AM - 9:45 AM Keynote Speaker Luciano Di Croce Epigenetic mechanisms governing cell differentiation and cancer processes 9:45 AM - 12:00 PM Session Ia: Writing Epigenetic Modifications (Chair: M. G. Rots) 9:45 AM - 10:15 AM Invited Speaker Nate Hathaway Chemically Activating Chromatin 10:15 AM - 10:30 AM Selected Speaker Isaac Hilton Deciphering the Histone Acetyl Code in Human Cells with dCas9-Based Epigenome Editing 10:30 AM - 11:00 AM Coffee Break 11:00 AM - 11:15 AM Selected Speaker Nicolas Marx CRISPR-Based Targeted Epigenetic Editing Enables Glyco-Engineering in Chinese Hamster Ovary (CHO) Cells 11:15 AM -12:00 PM Keynote Speaker Charles Gersbach Epigenome Editing to Program Cell Fate Decisions 12:00 PM - 2:00 PM Lunch Break 2:00 PM - 5:00 PM Session Ib: Writing Epigenetic Modifications (Chair: TBD) 2:00 PM -2:30 PM Invited Speaker Guoliang Xu DNA Methylation and Oxidation in Developmental Control 2:30PM -3:00 PM Invited Speaker Albert Jeltsch Setting of DNA methylation patterns - you see the environment 3:00 PM - 3:30 PM Coffee Break 3:30 PM - 3:45 PM Selected Speaker Alexandre Segelle Epigenome Editing of Alternatively Spliced Exons Relevant for the EMT Is Sufficient to Change Splicing Outcome 3:45 PM -4:00 PM Selected Speaker Tessa Swain Highly Effective Epigenome Editing and Gene Regulation By the Customizable dCas9-Sssavi Combinatorial Recruitment Platform 4:00 PM - 5:30 PM Poster Session Friday, September 13 7:30 AM - 12:00 PM Registration 9:00 AM - 12:00 PM Session II: Sensing and detection of epigenetic modifications (Chair: A. Jeltsch) 9:00 AM - 9:30 AM Invited Speaker Philipp Voigt Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Domains 9:30 AM - 10:00 AM Invited Speaker Marianne G Rots mtDNA methylation: is it or is it not (what is the true question?)? 10:00 AM -10:15 AM Selected Speaker Yuchen Gao Synthetic Heterochromatin Domain Formation Via CRISPR/dCas9 10:15 AM -10:30 AM Selected Speaker Hiroshi Kimura Modification-Specific Intracellular Antibodies for Monitoring Histone Modification and Transcription In Vivo 10:30 AM - 11:00 AM Coffee Break 11:00 AM -11:15 AM Selected Speaker Edita Kriukiene Precise DNA Epigenome Profiling: High-Resolution Economical Approaches for Detection of Genomic Cytosine Modifications 11:15 AM -11:30 AM Selected Speaker Philipp Rathert Dynamics and Wiring of Chromatin Regulators 11:30 AM -11:45 AM Selected Speaker Rodrigo Villasenor Engineered Chromatin Readers Reveal the Genome-Wide Proteome Composition at Key Chromatin States in Living Cells 11:45 AM -12:00 AM Selected Speaker Gergana Velikova Development of a Computational Tool for the Analysis of Bisulfite-Free DNA Sequencing Data 12:00 PM - 2:00 PM Lunch Break 2:00 PM - 4:30 PM Session III: Single cell Epigenetics (Chair: TBD) 2:00 PM - 2:30 PM Invited Speaker Albert Keung Human cerebral organoids model disease-relevant gene expression dynamics 2:30 PM - 3:00 PM Invited Speaker Carolina Florian Aging alters the epigenetic asymmetry of HSC division 3:00 PM - 3:30 PM Coffee Break 3:30 PM - 4:00 PM Invited Speaker Pernette Verschure Dynamic epigenetic regulation: Single cells can make a difference 4:00 PM - 4:15 PM Selected Speaker H. Courtney Hodges Regulation of Chromatin State in 3D Tissues 4:15 PM - 4:30 PM Selected Speaker Sai Ma Integrative Single-Cell Chromatin and Transcriptome Profiling Uncovers Cell-Type Specific Regulatory Interactions Saturday, September 14 7:30 AM - 12:00 PM Registration 9:00 AM - 9:45 AM Keynote Speaker Dave Segal Changing Your Mind: Targeted Epigenetic Editing in the Brain 9:45 AM - 10:30 PM Session IV: Epigenetic control of Development (Chair: TBD) 9:45 AM - 10:15 AM Invited Speaker Michael Zeisberg Epigenetic control of fibroblast activation 10:15 AM - 10:30 AM Selected Speaker Giovanni Carosso Precocious Neuronal Differentiation and Disrupted Oxygen Responses from KMT2D Loss in Kabuki Syndrome 10:30 AM - 11:00 AM Coffee Break 11:00 AM - 12:00 PM Session V: Cancer Epigenetics (Chair: TBD) 11:00 AM - 11:30 AM Invited Speaker Pilar Blancafort Epigenetic engineering in the cancer microenvironment 11:30 PM - 12:00 PM Invited Speaker Lucia Altucci Targeting Cancer Epigenome: strategies for prevention and treatment 12:00 PM - 12:45 PM Keynote Speaker Paola Arimodo Chemical Targeting of DNA and histone methylation to reprogram cells in human diseases: challenges and future perspectives 12:45 PM - 1:00 PM Closing Remarks