Technical Program | AIChE

Technical Program

Thursday, September 12

7:30 AM - 12:00 PM Registration
9:00 AM - 9:45 AM Keynote Speaker Luciano Di Croce Epigenetic mechanisms governing cell differentiation and cancer processes
9:45 AM - 12:00 PM Session Ia: Writing Epigenetic Modifications (Chair: M. G. Rots)
9:45 AM - 10:15 AM Invited Speaker Nate Hathaway Chemically Activating Chromatin
10:15 AM - 10:30 AM Selected Speaker Isaac Hilton Deciphering the Histone Acetyl Code in Human Cells with dCas9-Based Epigenome Editing
10:30 AM - 11:00 AM Coffee Break
11:00 AM - 11:15 AM Selected Speaker Nicolas Marx CRISPR-Based Targeted Epigenetic Editing Enables Glyco-Engineering in Chinese Hamster Ovary (CHO) Cells
11:15 AM -12:00 PM Keynote Speaker Charles Gersbach Epigenome Editing to Program Cell Fate Decisions
12:00 PM - 2:00 PM Lunch Break
2:00 PM - 5:00 PM Session Ib: Writing Epigenetic Modifications (Chair: TBD)
2:00 PM -2:30 PM Invited Speaker Guoliang Xu DNA Methylation and Oxidation in Developmental Control
2:30PM -3:00 PM Invited Speaker Albert Jeltsch Setting of DNA methylation patterns - you see the environment
3:00 PM - 3:30 PM Coffee Break
3:30 PM - 3:45 PM Selected Speaker Alexandre Segelle Epigenome Editing of Alternatively Spliced Exons Relevant for the EMT Is Sufficient to Change Splicing Outcome
3:45 PM -4:00 PM Selected Speaker Tessa Swain Highly Effective Epigenome Editing and Gene Regulation By the Customizable dCas9-Sssavi Combinatorial Recruitment Platform
4:00 PM - 5:30 PM Poster Session

Friday, September 13

7:30 AM - 12:00 PM Registration
9:00 AM - 12:00 PM Session II: Sensing and detection of epigenetic modifications (Chair: A. Jeltsch)
9:00 AM - 9:30 AM Invited Speaker Philipp Voigt Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Domains
9:30 AM - 10:00 AM Invited Speaker Marianne G Rots mtDNA methylation: is it or is it not (what is the true question?)?
10:00 AM -10:15 AM  Selected Speaker Yuchen Gao Synthetic Heterochromatin Domain Formation Via CRISPR/dCas9
10:15 AM -10:30 AM  Selected Speaker Hiroshi Kimura Modification-Specific Intracellular Antibodies for Monitoring Histone Modification and Transcription In Vivo
10:30 AM - 11:00 AM Coffee Break
11:00 AM -11:15 AM  Selected Speaker Edita Kriukiene Precise DNA Epigenome Profiling: High-Resolution Economical Approaches for Detection of Genomic Cytosine Modifications
11:15 AM -11:30 AM  Selected Speaker Philipp Rathert Dynamics and Wiring of Chromatin Regulators
11:30 AM -11:45 AM  Selected Speaker Rodrigo Villasenor Engineered Chromatin Readers Reveal the Genome-Wide Proteome Composition at Key Chromatin States in Living Cells
11:45 AM -12:00 AM  Selected Speaker Gergana Velikova Development of a Computational Tool for the Analysis of Bisulfite-Free DNA Sequencing Data
12:00 PM - 2:00 PM Lunch Break
2:00 PM - 4:30 PM Session III: Single cell Epigenetics (Chair: TBD)
2:00 PM - 2:30 PM Invited Speaker Albert Keung Human cerebral organoids model disease-relevant gene expression dynamics
2:30 PM - 3:00 PM Invited Speaker Carolina Florian Aging alters the epigenetic asymmetry of HSC division
3:00 PM - 3:30 PM Coffee Break
3:30 PM - 4:00 PM Invited Speaker Pernette Verschure Dynamic epigenetic regulation: Single cells can make a difference
4:00 PM - 4:15 PM Selected Speaker H. Courtney Hodges Regulation of Chromatin State in 3D Tissues
4:15 PM - 4:30 PM Selected Speaker Sai Ma Integrative Single-Cell Chromatin and Transcriptome Profiling Uncovers Cell-Type Specific Regulatory Interactions

Saturday, September 14

7:30 AM - 12:00 PM Registration
9:00 AM - 9:45 AM Keynote Speaker Dave Segal Changing Your Mind: Targeted Epigenetic Editing in the Brain
9:45 AM - 10:30 PM Session IV: Epigenetic control of Development  (Chair: TBD)
9:45 AM - 10:15 AM Invited Speaker Michael Zeisberg Epigenetic control of fibroblast activation
10:15 AM - 10:30 AM  Selected Speaker Giovanni Carosso Precocious Neuronal Differentiation and Disrupted Oxygen Responses from KMT2D Loss in Kabuki Syndrome
10:30 AM - 11:00 AM Coffee Break
11:00 AM - 12:00 PM Session V: Cancer Epigenetics  (Chair: TBD)
11:00 AM - 11:30 AM Invited Speaker Pilar Blancafort Epigenetic engineering in the cancer microenvironment
11:30 PM - 12:00 PM Invited Speaker Lucia Altucci Targeting Cancer Epigenome: strategies for prevention and treatment
12:00 PM - 12:45 PM Keynote Speaker Paola Arimodo  Chemical Targeting of DNA and histone methylation to reprogram cells in human diseases: challenges and future perspectives
12:45 PM - 1:00 PM Closing Remarks