| 7:30 AM - 12:00 PM |
Registration |
| 9:00 AM - 9:45 AM |
Keynote Speaker |
Luciano Di Croce |
Epigenetic mechanisms governing cell differentiation and cancer processes |
| 9:45 AM - 12:00 PM |
Session Ia: Writing Epigenetic Modifications (Chair: M. G. Rots) |
| 9:45 AM - 10:15 AM |
Invited Speaker |
Nate Hathaway |
Chemically Activating Chromatin |
| 10:15 AM - 10:30 AM |
Selected Speaker |
Isaac Hilton |
Deciphering the Histone Acetyl Code in Human Cells with dCas9-Based Epigenome Editing |
| 10:30 AM - 11:00 AM |
Coffee Break |
| 11:00 AM - 11:15 AM |
Selected Speaker |
Nicolas Marx |
CRISPR-Based Targeted Epigenetic Editing Enables Glyco-Engineering in Chinese Hamster Ovary (CHO) Cells |
| 11:15 AM -12:00 PM |
Keynote Speaker |
Charles Gersbach |
Epigenome Editing to Program Cell Fate Decisions |
| 12:00 PM - 2:00 PM |
Lunch Break |
| 2:00 PM - 5:00 PM |
Session Ib: Writing Epigenetic Modifications (Chair: TBD) |
| 2:00 PM -2:30 PM |
Invited Speaker |
Guoliang Xu |
DNA Methylation and Oxidation in Developmental Control |
| 2:30PM -3:00 PM |
Invited Speaker |
Albert Jeltsch |
Setting of DNA methylation patterns - you see the environment |
| 3:00 PM - 3:30 PM |
Coffee Break |
| 3:30 PM - 3:45 PM |
Selected Speaker |
Alexandre Segelle |
Epigenome Editing of Alternatively Spliced Exons Relevant for the EMT Is Sufficient to Change Splicing Outcome |
| 3:45 PM -4:00 PM |
Selected Speaker |
Tessa Swain |
Highly Effective Epigenome Editing and Gene Regulation By the Customizable dCas9-Sssavi Combinatorial Recruitment Platform |
| 4:00 PM - 5:30 PM |
Poster Session |
| 7:30 AM - 12:00 PM |
Registration |
| 9:00 AM - 12:00 PM |
Session II: Sensing and detection of epigenetic modifications (Chair: A. Jeltsch) |
| 9:00 AM - 9:30 AM |
Invited Speaker |
Philipp Voigt |
Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Domains |
| 9:30 AM - 10:00 AM |
Invited Speaker |
Marianne G Rots |
mtDNA methylation: is it or is it not (what is the true question?)? |
| 10:00 AM -10:15 AM |
Selected Speaker |
Yuchen Gao |
Synthetic Heterochromatin Domain Formation Via CRISPR/dCas9 |
| 10:15 AM -10:30 AM |
Selected Speaker |
Hiroshi Kimura |
Modification-Specific Intracellular Antibodies for Monitoring Histone Modification and Transcription In Vivo |
| 10:30 AM - 11:00 AM |
Coffee Break |
| 11:00 AM -11:15 AM |
Selected Speaker |
Edita Kriukiene |
Precise DNA Epigenome Profiling: High-Resolution Economical Approaches for Detection of Genomic Cytosine Modifications |
| 11:15 AM -11:30 AM |
Selected Speaker |
Philipp Rathert |
Dynamics and Wiring of Chromatin Regulators |
| 11:30 AM -11:45 AM |
Selected Speaker |
Rodrigo Villasenor |
Engineered Chromatin Readers Reveal the Genome-Wide Proteome Composition at Key Chromatin States in Living Cells |
| 11:45 AM -12:00 AM |
Selected Speaker |
Gergana Velikova |
Development of a Computational Tool for the Analysis of Bisulfite-Free DNA Sequencing Data |
| 12:00 PM - 2:00 PM |
Lunch Break |
| 2:00 PM - 4:30 PM |
Session III: Single cell Epigenetics (Chair: TBD) |
| 2:00 PM - 2:30 PM |
Invited Speaker |
Albert Keung |
Human cerebral organoids model disease-relevant gene expression dynamics |
| 2:30 PM - 3:00 PM |
Invited Speaker |
Carolina Florian |
Aging alters the epigenetic asymmetry of HSC division |
| 3:00 PM - 3:30 PM |
Coffee Break |
| 3:30 PM - 4:00 PM |
Invited Speaker |
Pernette Verschure |
Dynamic epigenetic regulation: Single cells can make a difference |
| 4:00 PM - 4:15 PM |
Selected Speaker |
H. Courtney Hodges |
Regulation of Chromatin State in 3D Tissues |
| 4:15 PM - 4:30 PM |
Selected Speaker |
Sai Ma |
Integrative Single-Cell Chromatin and Transcriptome Profiling Uncovers Cell-Type Specific Regulatory Interactions |
| 7:30 AM - 12:00 PM |
Registration |
| 9:00 AM - 9:45 AM |
Keynote Speaker |
Dave Segal |
Changing Your Mind: Targeted Epigenetic Editing in the Brain |
| 9:45 AM - 10:30 PM |
Session IV: Epigenetic control of Development (Chair: TBD) |
| 9:45 AM - 10:15 AM |
Invited Speaker |
Michael Zeisberg |
Epigenetic control of fibroblast activation |
| 10:15 AM - 10:30 AM |
Selected Speaker |
Giovanni Carosso |
Precocious Neuronal Differentiation and Disrupted Oxygen Responses from KMT2D Loss in Kabuki Syndrome |
| 10:30 AM - 11:00 AM |
Coffee Break |
| 11:00 AM - 12:00 PM |
Session V: Cancer Epigenetics (Chair: TBD) |
| 11:00 AM - 11:30 AM |
Invited Speaker |
Pilar Blancafort |
Epigenetic engineering in the cancer microenvironment |
| 11:30 PM - 12:00 PM |
Invited Speaker |
Lucia Altucci |
Targeting Cancer Epigenome: strategies for prevention and treatment |
| 12:00 PM - 12:45 PM |
Keynote Speaker |
Paola Arimodo |
Chemical Targeting of DNA and histone methylation to reprogram cells in human diseases: challenges and future perspectives |
| 12:45 PM - 1:00 PM |
Closing Remarks |