Technical Program | AIChE

Technical Program

*Please note this schedule is subject to change. Check back frequently for updates. Last updated 12.8.18 ...

*Please note this schedule is subject to change. Check back frequently for updates. Last updated 12.8.18

Monday, December 10

7:30 AM - 12:00 PM Registration
8:00 AM - 8:45 AM Morning Coffee & quick start breakfast
8:45 AM - 9:00 AM Welcome
9:00 AM - 9:45 AM Keynote Speaker - Fyodor Urnov, Genomics Institute/Altius Institute
9:45 AM - 12:00 PM Session 1: CRISPR-Cas Biology
  Chair: Chase Beisel, Helmholtz Institute
9:45 AM - 10:15 AM Molecular Technologies for Transcriptome Engineering, Invited Speaker: Patrick Hsu, Salk Institute
10:15 AM - 10:45 AM Coffee Break
10:45 AM - 11:15 AM Programmable RNA Recognition and Cleavage By N. Meningitidis CRISPR-Cas9, Invited Speaker: Yan Zhang, University of Michigan
11:15 AM - 11:30 AM Discovery of Widespread Type I and Type V CRISPR-Cas Inhibitors, Nicole Marino, University of California, San Francisco
11:30 AM - 11:45 AM Molecular Basis of Off-Target Effects in CRISPR-Cas9, Giulia Palermo, University of California, Riverside
11:45 AM - 12:00 PM Using Artificial Intelligence Algorithms to Improve CRISPR-Cas9 Specificity, Jin Liu, University of North Texas Health Science Center
12:00 PM - 1:30 PM Lunch
1:30 PM - 3:00 PM Session 2: Genome editing and DNA repair
  Chair: Alexis Komor, University of California, San Diego
1:30 PM - 2:00 PM Beyond Double Stranded DNA Breaks: Using Uracil and Inosine As Genome Editing Intermediates, Invited Speaker: Alexis Komor, University of California, San Diego
2:00 PM - 2:30 PM Genome Editing: From Fundamental DNA Repair Mechanisms to Cutting-Edge Applications, Invited Speaker: Yinan Kan, eGenesis
2:30 PM - 2:45 PM Isolation of Genomic DXR Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin, Gur Pines, University of Colorado Boulder
2:45 PM - 3:00 PM CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks, Chance Nowak, The University of Texas at Dallas
3:00 PM - 3:30 PM Coffee Break
3:30 PM - 5:45 PM Session 3: Beyond editing: Novel applications
  Chair: Harris Wang, Columbia University
3:30 PM - 4:00 PM Biological Recording of Cellular Events on CRISPR Tape, Invited Speaker: Harris Wang, Columbia University
4:00 PM - 4:15 PM CRISPR Adaptation as a Versatile Molecular Recording Platform for Fundamental Research and Biotechnology, Seth Shipman, University of California, San Francisco/Gladstone Institutes
4:15 PM - 4:30 PM High-Throughput Cas9-Mediated Genome Engineering for Eukaryotic Genome Interrogation, Xiaoge Guo, Harvard Medical School
4:30 PM - 4:45 PM Engineering Predictable, Tunable Gene Repression Based on Type I-E CRISPR Interference, Katia Tarasava, University of Colorado Boulder
4:45 PM - 5:00 PM Developmental Barcoding and Lineage Tracing in Mice Using Homing CRISPR, Reza Kalhor, Harvard Medical School
5:00 PM - 5:15 PM Mammalian Cells That Record Their Own History, Theresa Loveless, University of California, Irvine
5:15 PM - 5:45 PM Invited Speaker: Megan Palmer, Stanford University

Tuesday, December 11

8:15 AM - 12:00 PM Registration
8:15 AM - 9:15 AM Morning Coffee
9:15 AM - 11:45 AM Session 4: Clinical applications & CRISPR-based gene drives
  Chair: Omar Akbari, University of California, San Diego
9:15 AM - 9:45 AM Using CRISPR to Combat Human Disease Vectors, Invited Speaker: Omar Akbari, University of California, San Diego
9:45 AM - 10:00 AM Progress Towards Developing CRISPR-Based Genetic Pest Management Strategies for Spotted Wing Drosophila (SWD), Anna Buchman, University of California, San Diego
10:00 AM - 10:30 AM Coffee Break
10:30 AM - 11:00 AM Highly Efficient Single and Multi-Gene Knockout with CRISPR-Cpf1 in T Cells for the Development of Improved Cell Therapies, Invited Speaker: John Zuris, Editas Medicine
11:00 AM - 11:30 AM Therapeutic Strategies Via Genome Engineering: New Approaches and New Challenges, Invited Speaker: Prashant Mali, University of California, San Diego
11:30 AM - 11:45 AM A Novel Automation Platform for Generating CRISPR-Engineered Cells at Scale, Kevin Holden, Synthego
11:45 AM - 12:00 PM Creating Hereditary Persistence of Fetal Hemoglobin (HPFH) with CRISPR/Cas9 To Treat Beta-Thalassemia (Beta-Thal) and Sickle Cell Disease (SCD), TJ Cradick, CRISPR Therapeutics
12:00 PM - 1:45 PM Lunch
1:45 PM - 2:00 PM Session 5: Social, ethical, and economic implications of CRISPR-based technologies
1:45 PM - 2:00 PM Re-Framing Public Engagement to Promote Public Trust in CRISPR Technologies, Christian Ross, Arizona State University
2:00 PM - 3:00 PM Session 6: Delivery and Specificity of CRISPR-based tools (I)
2:00 PM - 2:30 PM A Growth-Based Screen Reveals Non-Canonical Pams for the Streptococcus Pyogenes Cas9, Invited Speaker: Chase Beisel, Helmholtz Institute
2:30 PM - 2:45 PM Developing New Tools and Technologies for Precision Genome Editing, Peter Cameron, Caribou Biosciences
2:45 PM - 3:00 PM Poster Setup
3:00 PM - 4:30 PM Poster Session/Reception


Wednesday, December 12

8:15 AM - 12:00 PM Registration
8:15 AM - 9:00 AM Morning Coffee
9:00 AM - 12:00 PM Session 7: Delivery and Specificity of CRISPR-based tools (II)
  Chairs: Mo Ebrahimkhani, Arizona State University & Shengdar Tsai, St. Jude Children's Research Hospital
9:00 AM - 9:30 AM Engineering Gene Regulatory Network for Synthetic Morphogenesis of Multicellular Mammalian Tissues, Invited Speaker: Mo Ebrahimkhani, Arizona State University
9:30 AM - 10:00 AM Illuminating the Genome-wide Activity of CRISPR-Cas Nucleases for Therapeutics, Invited Speaker: Shengdar Tsai, St. Jude Children's Research Hospital
10:00 AM - 10:30 AM Safer AAV-CRISPR-Cas Therapeutics, Invited Speaker: Wei Leong Chew, Genome Institute of Singapore
10:30 AM - 11:00 AM Coffee Break
11:00 AM - 11:15 AM Target Enrichment and High-Resolution NGS Analysis of on- and Off-Target CRISPR/Cas9 Editing Events, Ashley Jacobi, IDT
11:15 AM - 11:45 AM Genome Editing for Duchenne Muscular Dystrophy, Invited Speaker: Charles Gersbach, Duke University
11:45 AM - 12:00 PM Closing Remarks