International Conference on CRISPR Technologies

December 4-6, 2017

Presented by the Society for Biological Engineering (SBE), this conference will bring together leaders and trainees from the cutting edge of CRISPR technologies and their application to genome editing and beyond.

Technical Program

CRISPR technologies have been widely embraced for both basic and applied research. This space has rapidly moved forward since the first demonstration of Cas9-mediated genome editing with the discovery of new nucleases, the development of diverse and novel CRISPR applications for genome editing, gene regulation, in vitro applications, and the use of CRISPR technologies in diverse organisms including prokaryotes, plants, and animals. All of these diverse CRISPR applications will be discussed in this conference including the use of CRISPR in industrial biotechnology, agriculture, and human health; the intellectual property, ethical, and regulatory implications of CRISPR technologies; and the development, validation, and extension of novel CRISPR technologies and applications.

Conference Co-Chairs:

  • Chase Beisel, North Carolina State University
  • Benjamin Gray, Benson Hill Biosystems

Organizing Committee:

  • Rodolphe Barrangou, NC State University
  • Mark Cigan, Genus PLC
  • Gregory Davis, Sigma Millipore
  • Kevin Esvelt, MIT
  • Ryan Gill, University of Colorado Boulder
  • Fred Gould, NC State University
  • Sang Yup Lee, KAIST
  • Dipali Sashital, Iowa State University
  • Lisa Zannoni, Syngenta

Session Topics:

  • Genome editing and gene regulation in human health
  • Genome editing and gene regulation in industrial bacterial biotechnology
  • Genome editing and gene regulation in industrial eukaryotic biotechnology
  • Genome editing and gene regulation in agriculture
  • CRISPR technologies beyond genome editing and gene regulation
  • Achieving efficient delivery and editing
  • Horizons of CRISPR biology
  • CRISPR technologies and society

Featured Technical Events:

  • Roundtable discussions on technical hurdles to applying CRISPR technologies in different organisms
  • Panel discussion on the intersection of CRISPR technologies and society

Featured Keynote Speakers:

  • Charles Gersbach, Duke University
  • Eugene Koonin, NIH, NCBI, NLM

Invited Speakers:

  • Omar Abudayyeh, Broad Institute
  • Adair Borges, University of California, San Francisco
  • Anushree Chatterjee, University of Colorado Boulder
  • Mark Cigan, Genus PLC
  • Jonathan Gootenberg, Broad Institute
  • Kevin Holden, Synthego
  • Jennifer Kuzma, NC State University
  • Dave Ousterout, Locus Biosciences
  • Prashant Mali, University of California San Diego
  • Renee Wegrzyn, DARPA
  • Samira Kiani, Arizona State University
  • Zhixia Ye, Duke University 

Featured Speakers

Omar Abudayyeh

Omar O. Abudayyeh is an M.D.–Ph.D. student in the Harvard–Massachusetts Institute of Technology (MIT) Health Sciences and Technology program. In the laboratory of Feng Zhang at the Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA, his doctoral research focuses on the discovery and characterization of novel CRISPR proteins, such as Cpf1, C2c1 and Cas13a/C2c2, in bacteria for the purpose of expanding the genome-editing toolbox and studying mammalian biology. His recent work has focused on using the RNA-targeting CRISPR system Cas13 for building a transcriptome...Read more

Adair Borges

Adair Borges is a Biomedical Sciences PhD candidate at UCSF with a Bachelor of Science from University of Pittsburgh as a Barry M. Goldwater Scholar. Her doctoral research in Dr. Joseph Bondy-Denomy’s lab focuses on the discovery and characterization of a novel set of bacteriophage encoded proteins: anti-CRISPR proteins. These proteins, discovered by Dr. Bondy-Denomy in 2013, are the first proteins discovered to inhibit CRISPR-Cas function. The Bondy-Denomy lab studies the CRISPR/anti-CRISPR arms race in bacteriophages and bacteria to better understand microbial ecosystems and to...Read more

Anushree Chatterjee

Dr. Anushree Chatterjee is an Assistant Professor of Chemical and Biological Engineering at University of Colorado Boulder. The overarching goal of her research is to develop strategies for rationally engineering next-generation smart antimicrobials that can eliminate multi-drug resistant superbugs.Read more

Mark Cigan

Mark is the Trait Development Director at Genus R&D located near Madison, Wisconsin where he directs research which uses gene editing to improve animal health and production in livestock.

Prior to joining Genus in 2016, Mark was at DuPont Pioneer in Des Moines, Iowa for 24 years focusing primarily on studying plant reproductive biology for the development of hybrid seed production. Later in his career, Mark led a Genome Modification group which developed gene editing methods for commercial applications in maize, sorghum, wheat and soybean.

Mark earned his doctorate in...Read more

Charles A. Gersbach

Dr. Charles A. Gersbach is the Rooney Family Associate Professor at Duke University in the Departments of Biomedical Engineering and Orthopaedic Surgery, an Investigator in the Duke Center for Genomic and Computational Biology, and Director of the Duke Center for Biomolecular and Tissue Engineering.  His research interests are in genome and epigenome editing, gene therapy, regenerative medicine, biomolecular and cellular engineering, synthetic biology, and genomics.  Dr. Gersbach’s work has been recognized through awards including the NIH Director’s New Innovator...Read more

Jonathan Gootenberg

Jonathan S. Gootenberg is currently a Ph.D. candidate in the Harvard Systems Biology program, co-advised by Feng Zhang and Aviv Regev of the Broad Institute of MIT and Harvard. Jonathan's research combines computational and molecular approaches to discover and characterize new biological tools, with a specific focus on CRISPR/Cas proteins. These tools have diverse basic science and translation applications, including nucleic acid detection, genome-scale screening, and live-cell....Read more

Kevin Holden

Kevin Holden is Head of Synthetic Biology at Synthego in Redwood City, California where he is responsible for integrating synthetic biology workflows, such as CRISPR genome engineering, into novel engineering and automation platforms. He has over 10 years of biotechnology experience that includes synthetic biology, engineering metabolic pathways in microbes and collaborative research. Kevin earned his PhD in Microbiology from University of California, Davis. He is originally from the UK and immigrated to the US in his youth.Read more

Samira Kiani

Samira Kiani’s career is built around her passion for applying the CRISPR technology to synthetic biology. At Arizona State University, she has established her research program to combine CRISPR technology with Synthetic biology with an interest to develop safer and controllable gene therapies.Read more

Eugene Koonin

Dr. Koonin graduated from Moscow State University, Moscow, Russia and received his Ph.D. in Molecular Biology from the same University in 1983. He has been working in the fields of Computational Biology and Evolutionary Genomics since 1984. Dr. Koonin moved to the US in 1991, first, as a Visiting Scientist, and then, since 1996, as a Senior Investigator at the National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD.

The major research directions in Dr. Koonin's group include:

Evolutionary systems biology:...Read more

Jennifer Kuzma

Jennifer Kuzma is the Goodnight-NCGSK Foundation Distinguished Professor in the School of Public and International Affairs, and co-director of the Genetic Engineering and Society Center, at NC State University.  Prior to this, she was associate professor of science and technology policy at the University of Minnesota (2003-2013); study director at the U.S. National Academies of Science (NAS) (1999-2003); and an AAAS Risk Policy Fellow at the USDA (1997-1999). She has over 100 scholarly publications on emerging technologies and governance and has been studying this area for...Read more

Prashant Mali

Prashant Mali received a bachelor’s and master’s in Electrical Engineering from the Indian Institute of Technology Bombay, with a research focus on solid-state biosensors; and a doctorate in Biomedical Engineering at the Johns Hopkins University, with a research focus on human pluripotent stem cell engineering. During his postdoctoral fellowship in the Department of Genetics at the Harvard Medical School, he pioneered the development of the CRISPR-Cas systems for eukaryotic genome engineering. For his graduate work he received the Siebel Scholar Award in 2011, and in 2014 he...Read more

Dave Ousterout

Dr. Dave Ousterout is a co-founder and Chief Technology Officer for Locus Biosciences. Dave’s expertise is in protein engineering and early stage applications of new technologies to treat human diseases. Dr. Ousterout earned a BS in Biological & Environmental Engineering from Cornell University, an MS in Biomedical Engineering from Duke University and a PhD in Biomedical Engineering from Duke University. Dave completed his doctoral studies at Duke University in the lab of Dr. Charles Gersbach, where he developed novel gene editing approaches for correcting mutations that cause...Read more

Renee Wegrzyn

Dr. Renee Wegrzyn joined DARPA as a Program Manager in 2016. She is applying the tools of synthetic biology to support biosecurity and outpace infectious disease. She currently manages the Living Foundries and Safe Genes programs.

Prior to joining DARPA as a PM, Dr. Wegrzyn was a Senior Lead Biotechnologist at Booz Allen Hamilton, where she led a team that provided scientific and strategic support in the areas of biodefense, biosecurity, disruptive technologies, emerging infectious disease, neuromodulation, and synthetic biology to DARPA and other federal and private institutions....Read more

Zhixia Ye

Dr. Zhixia Ye received her B.S. in Chemistry from Beijing Institute of Technology, and Ph.D. in Chemistry from North Carolina State University. She is currently a Postdoctoral Associate at Duke University in the Department of Biomedical Engineering, advised by Michael D. Lynch. Her research interests are dynamic metabolic control using CRISPRi and controlled proteolysis based synthetic metabolic valves in 2-stage bioprocesses, enabling microbial metabolic network minimization. Network minimization helps development of robust and scalable high-throughput metabolic engineering, leading to...Read more