Share COBRA 2015 Regulation of metabolic activity in response to environmental and genetic perturbations is fundamental to the growth and maintenance of all cells. Linking the genome to its functioning metabolism is therefore of substantial interest in diverse biological research areas ranging from cancer to industrial biotechnology. To this end, Constraint-based Reconstruction and Analysis (COBRA) is rapidly being established as the method of choice for studying cellular metabolism in a global and unbiased fashion. COBRA-2015 aims to bring together the worldwide COBRA community to discuss novel tools and emerging applications. The meeting will offer a unique platform for the exchange of ideas and catalyze new multi-disciplinary collaborations. The following topics will be covered in the meeting: New metabolic models and simulation algorithms Omics and phenotypic data integration Biomedical applications of metabolic modeling Microbial cell factories Multi-scale modeling (whole cell models, host pathogen interactions and microbial communities) Organizing Committee Kiran Raosaheb Patil (EMBL, Heidelberg), chair Jason Papin (University of Virginia, Charlottesville) Ines Thiele (Luxembourg Centre for Systems Biomedicine, Luxembourg) Nathan Price (Institute for Systems Biology, Seattle) Markus Herrgård (NNF Center for Biosustainability, Denmark) Tomer Shlomi (Technion, Haifa)