March 2012 | AIChE

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March 2012

helical dryer model HD 40

March 5, 2012

The helical dryer model HD 40 is fully mobile and has a PLC-based control panel with wireless data logging for operation in hazardous areas. With a batch working capacity of 40 L, it can be used as a small production dryer or in trials for scale-up to production-size batch mixer/dryers. Its features include a heatable shaft/mixing assembly, bottom discharge, one mechanical seal, easy access for inspection, full cleanability with clean-in-place sprayers and compact dimensions so it can fit into kilo-labs and pilot-plants.

APSH flexible braid-reinforced, platinum-cured silicone hose

March 5, 2012

The APSH flexible braid-reinforced, platinum-cured silicone hose is now available with anti-wick seals to prevent liquid absorption within the hose walls. The anti-wick seal is created by molding silicone material to the cut end of a length of hose, which seals in the polyester yarn braid and prevents liquid absorption. It is especially helpful in applications where the hose is used as dip tubing, as it prevents fluids from becoming trapped within the hose walls. The APSH hose has undergone extensive physical, chemical and biological testing.

peristaltic pumping system

March 5, 2012

This single-use aseptic, peristaltic pumping system utilizes a closed-fluid pathway in which the containment tubing becomes the pump. The closed tubing system and gentle peristaltic motion permit contained cytotoxic liquids to be installed and dispensed within a convenient, easy-to-use, easy-to-change, fully contained fluid pathway.

Single Use Process Systems

March 5, 2012

Single Use Process Systems are comprised of silicone tubing and molded-silicone components, such as Tri-Clamp style fittings, container seals and bottle stoppers. Compared to traditional stainless steel systems, their design results in decreased production downtimes for cleaning activities, which increases productivity and reduces costs of materials and labor. Use of the silicone-based system simplifies cleaning validation procedures and reduces the risk of product cross-contamination.

BioFlo 415 benchtop fermentor

March 5, 2012

The BioFlo 415 benchtop fermentor provides the convenience of automatic sterilization-in-place with no need for an external steam supply. Using only laboratory water and the unit’s built-in heater, it provides rapid heat up and cool down, to speed research through production processes. This cGMP-compliant, validatable system is capable of controlling up to 32 process loops, including multiple thermal mass-flow controllers, as well as signals from up to 10 external scales, analyzers, sensors or other devices, for optimized process yields. A large, easy-to-use 15-in.

520/620/720 peristaltic pumps

March 5, 2012

  The 520/620/720 peristaltic pumps are designed for the accurate metering, dosing and transferring of sensitive fluids in sanitary environments, making them ideal for accurate filtration, fermentation, dispensing, coating and seamless integration into reusable or disposable bioprocess applications. The 720 Series peristaltic pump allows for production speed and flow control for high-capacity throughput, allowing the user to scale up from laboratory operations to production using the same pump interface familiar to the 520 and 620 user.

Peristaltic Pump

March 5, 2012

The closed fluid path that characterizes the peristaltic process of this pump assures that sterile product never comes in direct contact with any moving parts before being dispensed. Product passes from the bulk tank directly into sterile medical-grade silicone tubing that is placed onto the circular track of a filling head. A very gentle massaging motion lightly compresses the tubing against a proprietary dual-roller rotor to achieve a smooth, non-pulsing flow. This gentle pumping operation moves and dispenses even the most delicate liquids.

Tablet Press Lubricant Feeder

March 5, 2012

Adapted from the firm’s sanitary pharmaceutical twin-screw feeder, this tablet press lubricant feeder features the addition of a specialized gas venturi for aspiration of the lubricant (magnesium stearate) directly to the tablet press. The unit is available on a portable cart, in both volumetric and loss-in-weight models. It offers an automated, nearly constant feed rate, for uniform coating of the tablet tools, thereby avoiding sticking problems.

Aseptic M-7250CP constant-pressure system

March 5, 2012

Designed for use in the biopharmaceutical industry, the Aseptic M-7250CP constant-pressure system is a premium Microfluidizer processor that incorporates new system architecture and is able to integrate machine controls, functions and data recording onto a single common platform. Standard features include a Yokogawa data acquisition station (DAQ) that continuously monitors temperature, pressure and flow, enabling users to easily and cost-effectively record and print digital testing data.

MicroSeries agitator bead mills

March 5, 2012

The MicroSeries agitator bead mills produce particles sized less than 100 nm, which increases their absorption and delivery efficiency in the human body. The mills perform wet-grinding of small batches (0.14–0.5 L) with resulting particles down to 10–20 nm in size. This laboratory-scale equipment is completely scalable to full production size. Because product loss is minimized, the mills are suitable for grinding high-quality, high-priced and scarce pharmaceutical materials.

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