ICCT 2019 Preliminary Technical Program

*Please note this schedule is subject to change. Check back frequently for updates. Last updated: 9.4.19.

Monday, September 16th

7:00 AM - 12:00 PM Registration
9:00 AM - 9:15 AM Meeting Introduction
9:15 AM - 9:20 AM Keynote Introduction: Udi Qimron, Tel Aviv University
9:20 AM - 10:05 AM Keynote Speaker: Harnessing bacterial immune system for targeted genome engineering

Virginijus Siksnys, Vilnius University
Session 1: CRISPR-Cas Biology (Chair: Michael Terns, University of Georgia)
10:05 AM - 10:10 AM Session Chair Overview
10:10 AM - 10:35 AM Invited Speaker: DNA Uptake into CRISPR Loci

Michael Terns, University of Georgia
10:35 AM - 10:50 AM A Positive, Growth-Based PAM Screen Reveals Non-Canonical Motifs Recognized By the S. Pyogenes Cas9s

Daphne Collias, North Carolina State University
10:50 AM - 11:15 AM Break
11:15 AM - 11:40 AM Transcriptional and post-transcriptional regulation of type I and III CRISPR-Cas activity

Peter Fineran, University of Otago
11:40 AM - 12:05 PM Invited Speaker: RNA-targeting by Cas13a effector and DNA-proficient spacer acquisition in Type VI-A CRISPR-Cas system: How to encounter enemy, not die and prevent infection spreading

Ekaterina Semenova, Rutgers University
12:05 AM - 12:30 AM Invited Speaker: Functional Metagenomic Identification of Anti-CRISPR Proteins

Morten Sommer, The Technical University of Denmark
12:30 PM - 2:00 PM Lunch
Session 2: Foundational Technologies (Chair: Thorsten Stafforst, University of Tuebingen)
2:00 PM  - 2:05 PM Session Chair Overview
2:05 PM - 2:30 PM Invited Speaker: Engineering Programmable Tools to Target the Transcriptome

Thorsten Stafforst, University of Tuebingen
2:30 PM - 2:45 PM CRISPR-Cas9 Mediated Endogenous RNA Targeting in the Foodborne-Pathogen Campylobacter Jejuni

Sahil Sharma, University of Würzburg
2:45 PM - 3:00 PM Programmable Inhibition and Detection of RNA Viruses Using Cas13

Catherine A. Freije, Broad Institute
3:00 PM - 3:15 PM Massively Multiplexed Nucleic Acid Detection with Cas13

Cameron Myhrvold, Broad Institute
3:15 PM - 3:45 PM Break
3:45 PM - 4:00 PM CRISPR Switches: Non Sequence-Constrained RNA-Sensing Grnas

William Rostain, Genoscope
4:00 PM - 4:25 PM Transposon-encoded CRISPR-Cas systems facilitate programmable DNA integration

Sanne Klompe, Columbia University
4:25 PM - 4:50 PM Invited Speaker: Transcriptional recording by CRISPR spacer acquisition from RNA

Florian Schmidt, ETH Zurich
6:30 PM - 9:00 PM Ticketed Event: Dinner at the Weinkeller (time to walk or take public transportation)

Tuesday, September 17th

7:00 AM - 12:00 PM Registration
Session 3: Medical Applications (Chair: Kevin Holden, Synthego)
9:00 AM - 9:05 AM Session Chair Overview 
9:05 AM - 9:30 AM Invited Speaker: New technologies for enhancing the efficiency of CRISPR-based cell engineering at scale

Kevin Holden, Synthego
9:30 AM - 9:55 AM CRISPR-Powered Transistors for DNA Biosensing

Kiana Aran, Keck Graduate Institute
9:55 AM - 10:20 AM Invited Speaker: Enabling Precision Editing with CRISPR Hybrid RNA-DNA Guided Cas9

Paul Donohoue, Caribou Biosciences
10:20 AM - 10:50 AM Break
10:50 AM - 11:15 AM Invited Speaker: Inhibition and Recovery of CRISPR/spCas9 Activity at Closed Chromatin in a Human Cell Line

Karmella Haynes, Emory University
11:15 AM - 11:40 AM Invited Speaker: Improving CRISPR-Cas Performance with Chemical Modifications in Guide RNAs and Single-Cell DNA Analysis

Laurakay Bruhn, Agilent Research Laboratories
11:40 AM - 12:05 PM Invited Speaker: Improved methods and reagents for CRISPR homology-directed repair

Ashley Jacobi, IDT
12:05 PM - 1:30 PM Lunch
1:30 PM - 1:55 PM Invited Speaker: Genome Editing: From Fundamental DNA Repair Mechanisms to Cutting-Edge Applications

Yinan Kan, eGenesis
1:55 PM - 2:20 PM Invited Speaker: Targeting monogenetic liver diseases by CRISPR/Cas9

Gerald Schwank, ETH Zürich
2:20 PM - 2:45 PM Targeted Transcriptional Modulation with Type I CRISPR-Cas Systems in Human Cells

Adrian Pickar-Oliver, Duke University
2:45 PM - 3:00 PM Ccexo: A New Tool for the Enhanced Genome Editing

Duško Lainšček, National Institute of Chemistry, Slovenia
3:00 PM - 3:30 PM Break
Session 4: Agricultural Applications  (Chair: Tom Schrieber, IPB Halle)
3:30 PM - 3:35 PM Session Chair Overview
3:35 PM - 4:00 PM Invited Speaker: How to Turn Negative into Positive: Application of CRISPR Endoribonuclease Csy4 As a Negative Operator to Detect Negative Signals in Planta

Tom Schreiber, IPB Halle
4:00 PM - 4:15 PM Genome Editing for Consumer Traits in Fresh Produce

Sabine Fraebel, Pairwise
4:30 PM - 7:00 PM Posters and reception

Wednesday, September 18th

7:00 AM - 12:00 PM Registration
Session 5: Societal Impacts (Chair: Chase Beisel, University of Würzburg)
9:00 AM - 9:05 AM Keynote Introduction and Session Introduction
9:05 AM - 9:50 AM Keynote Speaker: Population genome editing for the control of the human malaria vector Anopheles gambiae

Andrea Crisanti, Imperial College
Session 6: Bacterial Applications (Chair: David Bikard, Pasteur)
9:50 AM - 9:55 AM Session Chair Overview
9:55 AM - 10:20 AM Invited Speaker: Silencing Genes with dCas9: A Story of Fine-Tuned Control, High-Throughput Screens and Surprising Toxicity

David Bikard, Pasteur
10:20 AM - 10:40 AM Break
10:40 AM - 10:55 AM The Role of NHEJ Double-Strand Break Repair on CRISPR-Cas9 Targeting in Pseudomonas Putida KT2440

Laura Chacón Machado, Skolkova Institute
10:55 AM - 11:20 AM Invited Speaker: A Minimal CRISPR-Cas3 System for Rapid Large-Scale Genome Manipulation

Lina Leon, University of California, San Francisco
11:20 AM - 11:35 AM A Simple and Fast Method for Transcriptional Inactivation in Synechocystis PCC6803 Using CRISPR-Interference from a Single Plasmid

Prithwiraj Kirtania, Hungarian Academy of Sciences
11:35 AM - 12:00 PM Invited Speaker: Enhancing Bacterial Crispri Specificity Usingâ Active ThermoCas9 and an Anticrispr Protein

Ioannis Mougiakos, Wageningen University
12:00PM - 12:15 PM Final Remarks