Technical Program | AIChE

Technical Program

*Note: This schedule is preliminary and is subject to change* ...

*Note: This schedule is preliminary and is subject to change*


Thursday, September 20th

 
8:30 AM - 12:00 PM REGISTRATION
9:30 AM - 9:40 AM WELCOMING REMARKS
9:40 AM - 10:25 AM KEYNOTE SPEAKER: Pathology from the Molecular Scale on Up Garry Nolan, Stanford University
10:25 AM - 11:25 AM SESSION 1: CD19 STORY: WHAT HAS WORKED, AND LESSONS LEARNED FROM THE SUCCESS OF CAR T CELL THERAPY
10:25 AM - 10:55 AM

INVITED SPEAKER: Defined Composition CD19 CAR-T cells for Adult B cell Malignancies

Cameron Turtle, Fred Hutchinson Cancer Research Center

10:55 AM - 11:10 AM

Tales of Three CAR T Cell Start-Ups 

Ronald Dudek, Lentigen Technology, Inc.

11:10 AM - 11:25 AM

Systematic Investigation of Parameters That Affect In Vivo CAR-T Cell Function

Ximin Chen, University of California, Los Angeles

11:25 AM - 11:55 AM BREAK
11:55 AM - 1:40 PM SESSION 2: CHALLENGES AND OPPORTUNITIES FOR CELL THERAPIES FOR SOLID TUMORS (ANTIGENS, METABOLISM, AND THE TUMOR MICROENVIRONMENT)
11:55 AM - 12:25 PM

INVITED SPEAKER: Genetic Engineering Approaches to Improve CAR T Cell Anti-Tumor Activity for Solid Tumors

Giedre Krenciute, St. Jude Childrens Research Hospital

12:25 PM - 12:55 PM

INVITED SPEAKER: Signal Control of CD8 T Cell Immune Responses

Xiaoping Zhong, Duke University School of Medicine

12:55 PM - 1:10 PM

Macrophage-Mediated Delivery of Light Activated Nitric Oxide Prodrugs with Spatial, Temporal and Concentration Control

Michael A. Evans, Harvard University

1:10 PM - 1:25 PM

Tumor Cell Intrinsic Factors Dictate Immune Cell Infiltration and Response to Immunotherapy

Katelyn T. Byrne, Parker Institute for Cancer Immunotherapy

1:25 PM - 1:40 PM

Self-Cancellation Mechanism of the PD-L1/PD-1 Pathway

Enfu Hui, University of California, San Diego

1:40 PM - 2:45 PM LUNCH
2:45 PM - 3:15 PM SESSION 3: GENOME EDITING FOR THERAPEUTIC CELL ENGINEERING: EFFICACY VS SAFETY
2:45 PM - 3:15 PM

INVITED SPEAKER: Reprogramming Human T Cell Circuitry

Alexander Marson, University of California, San Francisco

3:15 PM - 4:30 PM SESSION 4: INDUSTRY PANEL
3:15 PM - 4:30 PM

Justin Farlow, Co-Founder and CTO, Serotiny, Inc.

Julie Norville, Co-Founder, JURA Bio, Inc.

Elizabeth Wood, Co-Founder, JURA Bio, Inc.

4:30 PM - 6:00 PM Poster Session and Networking Reception


Friday, September 21st

 
8:00 AM - 12:00 PM REGISTRATION
8:45 AM - 8:50 AM OPENING REMARKS
8:50 AM - 9:35 AM

KEYNOTE SPEAKER: Translation of YESCARTA®, a first-in-class CAR T cell product for Non-Hodgkin Lymphoma

Adrian Bot, Kite Pharma

9:35 AM - 11:50 AM SESSION 5: IMMUNOTHERAPY: IMMUNE CELLS OTHER THAN CONVENTIONAL T CELLS
9:35 AM - 10:05 AM

INVITED SPEAKER: Manipulating Tregs to Control Tolerance in Autoimmunity and Cancer

Qizhi Tang, University of California, San Francisco

10:05 AM - 10:35 AM

INVITED SPEAKER: Immunoengineering for Improved Antitumor Immunity

Michael Goldberg, Dana-Farber Cancer Institute

10:35 AM - 11:05 AM BREAK 
11:05 AM - 11:20 AM

In Vivo Metabolic Labeling and Targeted Modulation of Dendritic Cells for Enhanced Cancer Immunotherapy

Hua Wang, Harvard University

11:20 AM - 11:35 AM

Lentiviral-mediated FOXP3 gene transfer to convert CD4+ T cells to Treg cells: a suitable method for immunotherapy

Rosa Bacchetta, Stanford University

11:35 AM - 11:50 AM

Generation of Antigen-Specific Germinal Center-like B Cells As a Next-Generation Immunotherapy

Hannah Song, Georgia Institute of Technology

11:50 AM - 12:35 PM SESSION 6: TCR T CELLS
11:50 PM - 12:20 PM

INVITED SPEAKER: Adoptive Cell Therapy: Enabling Technologies for Endogenous T Cell (ETC) Therapy of Cancer

Cassian Yee, MD Anderson Cancer Center

12:20 PM - 12:35 PM

Novel Engineering Approaches for Developing Therapeutically Relevant T Cell Receptors for Use in T Cell Therapies for Multiple Sclerosis (MS)

Elissa Leonard, University of Texas at Austin

12:35 PM - 2:00 PM LUNCH
2:00 PM - 3:30 PM SESSION 7: NOVEL DELIVERY TECHNOLOGY FOR CELL THERAPIES
2:00 PM - 2:30 PM

INVITED SPEAKER: Enhancing T cell Immunotherapy Using Responsive Biomaterials

Li Tang, École polytechnique fédérale de Lausanne (EPFL)

2:30 PM - 3:00 PM

INVITED SPEAKER: In Situ Programming of Therapeutic T Cells Using Synthetic Nanoparticles

Matthias Stephan, University of Washingto, Seattle, WA

3:00 PM - 3:15 PM

Treating Diabetes with a Cup of Coffee

Daniel Bojar, ETH Zurich

3:15 PM - 3:30 PM

Single Use Disposable Biosettler Removes the Dead Cells and Cell Debris Selectively to Increase the Viability Percentage of Mammalian Cells (e.g. CAR-T) during Expansion

Dhinakar Kompala, Sudhin Biopharma Co


Saturday, September 22

 
7:00 AM - 8:00 AM REGISTRATION
8:00 AM - 8:10 AM OPENING REMARKS
8:10 AM - 9:55 AM SESSION 8: UNDERSTANDING AND ENGINEERING PERSISTENCE
8:10 AM - 8:40 AM

INVITED SPEAKER: Improving the expansion and persistence of CAR T-cells for solid tumors

Cliona Rooney, Baylor College of Medicine

8:40 AM - 9:10 AM

INVITED SPEAKER: Towards the development of a dual antigen AND-gate CAR T for prostate cancer

Amy Gilbert, Kite Pharma

9:10 AM - 9:25 AM

Supervised Machine Learning Methods for Chemometric Modeling and Predicting in Biotherapeutic Manufacturing Processes

Thomas Li, Pfizer

9:25 AM - 9:40 AM

Decision Tools in the Assistance of the CAR T-Cell Industry

Maria Papathanasiou, Imperial College, London

9:40 AM - 9:55 AM

Drug Response Landscape of BRAF-Mutated Melanoma Cells: Non-Quiescent "Idling Population State" As an Alternative Drug Persistence

Bishal Paudel, Vanderbilt University

9:55 AM - 10:10 AM

Functionalized Microcarriers for Enhanced CAR T Cell Manufacturing

Nate Dwarshuis, Georgia Institute of Technology

10:10 AM - 10:25 AM BREAK 
10:25 AM - 12:15 PM SESSION 9: SYNTHETIC BIOLOGY FOR CELLULAR IMMUNOTHERAPY
10:25 AM - 10:55 AM

INVITED SPEAKER: Engineering the Next Generation of Immune Cell Therapies

Kole Roybal, University of California, San Francisco

10:55 AM - 11:25 AM

INVITED SPEAKER: Engineering Biological Computers for Human Health Applications

Tim Lu, Massachusetts Institute of Technology

11:25 AM - 11:40 AM

Synthetic Transcriptional Regulation for Human Cell Therapy

Divya Israni, Boston University

11:40 AM - 11:55 AM

Design Driven Engineering of Extracellular Sensors for the Development of Mammalian Cell-Based Therapies

Taylor Dolberg, Northwestern University

11:55 AM - 12:10 PM

Thermal Bioswitches for Noninvasive Control of Cell Function

Dan Piraner, California Institute of Technology

12:10 PM - 12:15 PM Closing Remarks