CEP: September 2016 This issue’s SBE supplement showcases recent advances in synthetic biology. The first two articles examine new additions to the synthetic biology toolbox — massively parallel DNA synthesis and CRISPR-Cas systems. The final article in the supplement describes how one company found commercial success by establishing an integrated computational and experimental bioengineering platform that harnesses the synthetic biology toolbox. Other topices in this issue include designing drug-delivery nanoparticles; minimizing biofouling of RO membranes; and ammonia production. Editorial Healthy Employees, Healthy Company A new book featured in this month's Books department, The Healthy Workplace, caught my attention. Author Leigh Stringer notes that "leading companies and organizations are seeing immediate and long-lasting benefits from investing in the health and well-being of their employees. The most obvious benefits to the bottom line are the avoidance of health care costs, but companies that make investments in employee health are also seeing increases in creativity, engagement, and productivity, and as a result, business growth." Read more Share Designing Drug-Delivery Nanoparticles September2016On The HorizonAaron Anselmo, Samir MitragotriNanoparticles for drug delivery can be better designed by modeling the body as unit processes connected by the vascular system. Each organ and organ function can be represented as a unit process on organ-on-a-chip devices. Minimize Biofouling of RO Membranes September2016Reactions and SeparationsAnne Arza, Jane KuceraChemical and physical disinfection of feedwater to a reverse osmosis (RO) membrane helps to prevent fouling and maintain efficient operation. Introduction to Ammonia Production September2016Back To BasicsVenkat Pattabathula, Jim RichardsonAmmonia is critical in the manufacturing of fertilizers, and is one of the largest-volume synthetic chemicals produced in the world. This article explores the evolution of ammonia production and describes the current manufacturing technologies. SBE Supplement: Synthetic Biology - SBE Update: The Expanding Synthetic Biology Toolbox September2016SBE Special SectionDarlene SchusterSynthetic biology is growing in both interest and impact. This developing field combines techniques from such disciplines as genetic engineering, molecular engineering, systems biology, and computer engineering. The scientists and engineers who work in this field design and construct novel biological entities (e.g., proteins, genetic circuits, metabolic pathways, etc.) and redesign existing biological systems. SBE Supplement: Synthetic Biology - Rewriting DNA Synthesis September2016SBE Special SectionEmily LeproustTraditional methods of DNA synthesis are slow and costly, and hinder the design-build-test cycle for creating optimal gene sequences and protein variants. This article presents a novel approach that will allow researchers to explore synthetic biology’s full potential. SBE Supplement: Synthetic Biology - Engineering Genes with CRISPR-Cas9 September2016SBE Special SectionMichelle L. Luo, Chase L. BeiselEngineered CRISPR-Cas systems allow scientists to make programmable, precise edits to DNA. This technology has the potential to cure human diseases and transform agriculture. SBE Supplement: Synthetic Biology - A Bioengineering Platform to Industrialize Biotechnology September2016SBE Special SectionStephanie CullerAn integrated bioengineering platform that harnesses the synthetic biology toolbox is the key to an economically viable commercial bioprocess. SBE Supplement: Synthetic Biology (Full 25-Page Supplement) September2016SBE Special SectionRewriting DNA Synthesis; Engineering Genes with CRISPR-Cas9; A Bioengineering Platform to Industrialize Biotechnology Copyright Permissions: Would you like to reuse content from CEP Magazine? It’s easy to request permission to reuse content. Simply click here to connect instantly to licensing services, where you can choose from a list of options regarding how you would like to reuse the desired content and complete the transaction.