CEP: April 2016

This month's Back to Basics article on mammalian cell culture describes how mammalian cells are derived, their utility, and the proceses that harness their full potential. Other topics in this issue include combustible-dust hazard analysis, water conservation and preventing caking of bulk solids.


Swimming Against the Tide: Making Water Management a Priority

Just after I finished reading Sharon Nolen’s Critical Issues article, “Leveraging Energy Management for Water Conservation” (pp. 41–47), the headline of a New York Times op-ed piece by Charles Fishman, “The Water Data Drought,” caught my attention. Since we published a special section on big data last month, I was doubly curious.

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Making Sense of Combustible-Dust Hazard Analysis

Michelle Murphy
Several standards on combustible dust contain provisions for conducting process hazard analyses. This article summarizes the requirements and presents a simple approach to meet them.

An Introduction to Mammalian Cell Culture

Back To Basics
Tung S. Le, Meghan McCann, Samira M. Azarin, Dr. Wei-Shou Hu
Mammalian cell culture is at the core of biomanufacturing therapeutic proteins and viral vaccines. Find out how mammalian cells are derived and cultivated, and what opportunities this field holds.

Leveraging Energy Management for Water Conservation

Critical Issues
Sharon Nolen, P.E.
Growing concerns about the availability of clean water are driving companies to include water conservation in their sustainability initiatives. Instead of reinventing the wheel, adapt your energy-management program for water conservation.

Prevent Caking of Bulk Solids

Fluids and Solids Handling
Greg Mehos, P.E.
Understanding the mechanisms behind caking, identifying key process variables and product specifications, and testing samples to predict the increase in cohesive strength of a powder over time are key to preventing and solving caking problems.
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