2025 SBE's James E. Bailey Award & D.I.C. Wang Award Lectures | AIChE

These awards are sponsored by the Society for Biological Engineering.

SBE's James E. Bailey Award

The Society for Biological Engineering's Bailey award recognizes outstanding contributions in the field of biological engineering. In memory of Professor James Bailey for his many pioneering contributions to biotechnology, this award is presented to an individual who has had an important impact on biological engineering and whose achievements have advanced the profession.

James Bailey's educational legacy touched many modern biochemical and biological engineers in the profession today. The award is presented to an individual who embodies the spirit of James Bailey, one that is a pioneer, a mentor, an innovator, an integrator of biology and engineering, a teacher, and whose achievements have provided a major impact to the field of biological engineering.

We are pleased to announce Daniel G. Anderson, Massachusetts Institute of Technology (MIT), is the recipient of the 2025 James E. Bailey Award.

Engineering Materials for Genetic Medicine 

Over the past several decades, the materials that we use to build medical devices and drug delivery systems have advanced dramatically, leading to new treatments for human disease.  Here we will discuss materials that have been developed to deliver drugs inside of our cells.  These synthetic nanoparticulate drug delivery systems have opened the door to new types of genetic therapies for the prevention, treatment, or even curing of human diseases.  Perhaps the most famous examples today are the nanoparticles made from lipids and mRNA as vaccines for COVID.  However, vaccines represent only a small part of the broad potential use of nanoparticles and RNA as therapeutics. We will describe the development and use of these technologies, as well as their potential as therapies for a range of different diseases.

 

D.I.C. Wang Award Lecture

The award lecture will be presented to a distinguished biochemical engineer and biotechnologist by the Biochemical Technology Division of the American Chemical Society and by the Food, Pharmaceuticals and Bioengineering Division of the American Institute of Chemical Engineers and the Society of Biological Engineering.

We are pleased to announce Costas D. Maranas, Pennsylvania State University, is the recipient of the 2025 D.I.C. Wang Award.

Supported by the AIChE Foundation

Optimization and AI-guided Explorations in Biochemical Engineering

In this talk, we will review ongoing efforts towards creating computational tools to elucidate insight and support engineering decisions in metabolism and protein design. We will highlight earlier contributions leveraging mathematical optimization to help reconstruct, analyze and redesign metabolic networks as well as design proteins with desired binding characteristics. We will next pivot towards more recent work that fuses both protein and metabolism design tasks to realize the assembly of carbon and energy efficient biosynthetic pathways by seamlessly blending known biochemical reactions with de novo steps. The emerging role of AI and large-language models will next be detailed in the context of enzyme kinetics and design prediction. Moving from stoichiometric to kinetic models of metabolism with genome-wide coverage, parameterization challenges will be described for several microbial production hosts. Insight and lessons gained from the application of these tools on a variety of biochemical engineering challenges that we have faced as members of the DOE bioenergy centers CBI and CABBI as well as the NSF AI Molecular Maker Laboratory Institute will be provided.

 

Biotechnology Progress Award for Excellence in Biological Engineering Publication

The Biotechnology Progress Award for Excellence in Biological Engineering Publication winner will also be recognized during the James E. Bailey Award session.

The Biotechnology Progress Award for Excellence in Biological Engineering Publication recognizes outstanding contributions to the literature in biomedical engineering, biological engineering, biotechnology, biochemical engineering and related fields. The award, which is presented annually at the AIChE Annual Meeting, celebrates excellence and foundational contributions to biotechnology and biological engineering through a body of work: a seminal paper, a review, a research report, or other material of significant interest and importance.

We are pleased to announce this year's Biotechnology Progress Award for Excellence in Biological Engineering Publication winner, Maciek Antoniewicz, Professor, University of Michigan.