March 2012 | AIChE

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March 2012

125TC Sampling System

March 5, 2012

The 125TC sampling system is used to take samples of powder as well as pasty media from reactors, dryers, filters, nutsches and pipes under vacuum or pressure. Its functional principle is based on a self-sealing piston which expands when closed. Since neither O-rings nor a packing are used for sealing, absolute tightness with zero dead space is guaranteed. It is now possible, due to quick-coupling connections, to easily dismantle the valve in order to completely clean all the parts. The system can be flexibly adapted to any vessel or pipe.

Model 4T Laboratory Filter

March 5, 2012

Designed for use in laboratories to perform filtration trials and scalability studies, the Model 4T laboratory filter is constructed from Type 316 stainless steel with protected Pyrex glass cylinder for filtration up to 30 psig. Stainless steel cylinders are available for pressures up to 50 psig. Small constant flow pumps, compressed air or inert gas can be used to flow liquid through the filter media. The 4T Laboratory Filter has a media diameter of 47 mm with EPDM gasket material. The filtration area is 13.8 cm2 with a pressure limit of 80 psi.

Major Study on Materials Just Commissioned

March 5, 2012

Bringing 50 years of experience to the biopharmaceutical industry with its advanced research and capabilities applied through a range of CIP technology and engineering services, this firm will announce the commissioning of a leading research university to conduct a major new study of the impact various materials and surface finishes have on the cleanability of biofilms and other soils.

Hygienic Opti-Gard

March 5, 2012

The hygienic Opti-Gard is equipped with a non-fragmenting, reverse-acting rupture disk with a smooth, uninterrupted surface finish to reduce contamination and maximize stream SIP and CIP procedures. To facilitate installation, the system is designed to fit directly between ISO2852 standard food industry couplings and clamp fittings. Opti-Gard features a performance tolerance of only 5% across a wide range of burst pressures and a 95% operating ratio.

Compact Isolator Manipulates Toxic Products

March 5, 2012

This compact isolator has been designed to manipulate toxic products ensuring top security levels for the operator and for the environment. It provides high-tech solutions in a compact unit suitable for any chemical, pharmaceutical or biotechnological laboratory, such as bag-in/bag-out for the HEPA filters, automatic pressure control and adjustment, liquid atomizing system, ULPA filtering system for technical gases and a sophisticated software that via PLC controls all the system components.

Process Analytical Technology (PAT) Tool

March 5, 2012

Implemented at leading FDA-regulated manufacturing sites, eProcessinfo is a powerful Process Analytical Technology (PAT) tool that transforms process data into knowledge to gain process understanding. eProcessinfo helps determine the sources of process variability and understand the relationships among critical process factors.

Clean Sweep Mixers

March 5, 2012

The Clean Sweep mixer’s new design revolutionizes mixing technology by utilizing a swinging motion instead of the customary rotating motion. The mixer features a FDA/USP Class VI elastomeric seal. The Clean Sweep mixer is ideal for low-shear, high-purity mixing applications and easily accommodates mixing at low-liquid levels. This unique type of mixer has a new impeller with specially shaped blades optimized to provide global mixing throughout the vessel.

Pharmaceutical Expertise Available

March 5, 2012

This company provides: onsite CIP testing, vessel evaluation, leak repair, heat transfer surface repair, spot electropolish, refinish vessel interior, and in-house modifications. With more than 20 years of experience in pharmaceutical vessels, the firm meets ASME repair requirements, and provides any additional documentation that may be requested.

Continuous Biowaste Inactivation (CEITM) System

March 5, 2012

The Continuous Biowaste Inactivation (CEITM) system consists of three zones — holding tank, waste deactivation and cooling. Options are available for sealless pumps, PLC control and monitoring, and pH control before discharging. Waste is stored in the holding tank, which is an ASME Type 316 stainless steel tank equipped with a filtered vent, inspection port and openings for clean-in-place media. The waste is deactivated by pumping it into steam or electric-traced heat exchangers that are maintained at 300°F. The deactivated waste is then pumped through a cooling exchanger.

Assess Process Containment Efficiency

March 5, 2012

This firm offers consulting and lab services for the testing of containment efficiency in solids manufacturing, packaging and handling. Containment performance is an important factor in evaluating and understanding the risks of operator exposures and process contamination in pharmaceutical manufacturing. Testing can be performed on equipment, processes components or operations either in a controlled environment during the process design stage, or in a manufacturing environment for existing equipment or processes.

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