March 2012 | AIChE

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March 2012

Flexofill Monoblock Machine

March 5, 2012

The Flexofill monoblock machine is a combination filling and closing innovation for products from liquid to paste consistencies. Ideal for the pharmaceutical and cosmetic industries, the Flexofill has the capability to handle press-in, screw and crimp closures, spray pumps with dip tubes, roll-on, pipette closures, measuring cups, veterinary syringes to name a few. Manufactured GMP-compliant, the Flexofill is modular in construction, offering a small footprint.

BioFlo Pro Fermentors and Bioreactors

March 5, 2012

This company recently expanded its line of pilot and production-scale bioprocessing systems to include fermentors sized 75–3,000 L and cell culture bioreactors to 500 L. The BioFlo Pro fermentors and bioreactors are modular in design, offering ready customization, quick delivery and the ability to expand system capabilities as needs change. All utilize robust, industry-standard components for dependable operation, and a validatable, GaMP-compliant, programmable-logic controller (PLC) for easy integration into any production facility.

Laser Ablation

March 5, 2012

Laser ablation (LA) is a popular preparation methods for thin films and fine particles in the nanometer regime. By controlling the laser wavelength and fluence, this technology can be applied not only to inorganic materials, but also to organic compounds like drugs or proteins. One of the most attractive applications is to prepare nanoparticles of sparingly soluble drugs, in order to increase its dissolution rate, thus increasing the bioavailability. This firm’s LA system enables deposition of these nanoparticles on a substrate, as well as on particulate systems.

Vispro System

March 5, 2012

Developed to transfer viscous products from the manufacturing site to other locations, the Vispro system uses an air pressure to raise a plunger located inside the smooth walled 200-L stainless steel drum. The product is discharged through an outlet in the unit’s lid. The system has various safety features and is designed to minimize loss with transferring products.

SelRO Nanofiltration Membranes

March 5, 2012

The SelRO nanofiltration membranes provide outstanding chemical and thermal stability to satisfy the demanding requirements of pharmaceutical processes involving high and low pH, high temperature and organic solvents media. Most nanofiltration membranes previously available were limited to aqueous applications within the pH range from 2 to 11. The SelRO membranes can be operated within a pH range of 0–14. They enable the concentration of pharmaceutical intermediates in aqueous solutions, which may also contain organic solvents such as methanol, ethanol, acetone, acetonitrile and others.

7800 Series Universal Seal

March 5, 2012

The heavy-duty gas-lubricated 7800 Series universal seal is ideal for use in a wide variety of mixing and agitating equipment, as well as other top entry mixer applications. The seal uses modular hardware, allowing for maximum interchangeability and efficiency. This convertible format will support contacting dry, contacting wet, non-contacting or a combination of non-contacting and dry contacting seal technology without the need to change any adaptive hardware. The patented grooved rotor allows equal lift in the presence of up to 0.125- in.

Safely Load and Charge APIs

March 5, 2012

The Charge Tube is a special system designed for the safe loading and charging of APIs supplied in various drum sizes into a process vessel IBC or other charging application, while providing extreme levels of containment and control over the environmental conditions within the isolation system. The Charge Tube consists of single vessel charging glove box, which is connected directly to a process vessel, charge port, or process hopper via a discharge valve in the base of isolator.

InfoBatch Web Server

March 5, 2012

The InfoBatch Web Server enables authorized users to generate comprehensive batch and production reports from standard desktop Internet browsers. The server enforces the InfoBatch security model, ensuring compliance with FDA 21 CFR Part 11. InfoBatch enables manufacturers to maximize quality and productivity by demonstrating that GMP is maintained through all phases of batch production. Users can quickly create comprehensive exception and production reports without programming.

Partica LA-950 laser diffraction particle size analyzer

March 5, 2012

The Partica LA-950 laser diffraction particle size analyzer has a wide measurement range (0.01–3000µm), fast analysis time (one minute sample-to-sample), and powerful wet- and drysample dispersion systems. The easy-to-use optical system provides extreme accuracy, precision and resolution.

Fenwal PistonFire Suppressor

March 5, 2012

The innovative Fenwal PistonFire suppressor is designed to discharge an explosion suppressant into a process vessel in milliseconds without the use of explosive actuators. It’s safer to transport and store than conventional explosive actuators and features a supervisory switch to meet OSHA lockout/tagout requirements. The Fenwal PistonFire suppressor has a longer (five years) actuator service life to reduce maintenance costs. Its field-rechargeable design minimizes production downtime in the event of a suppressed explosion and saves on recharge costs.

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