Share March, 2015Nanoparticles (NPs) loaded with therapeutics provide a way to target the delivery of drugs to specific locations in the body. When injected intravenously, however, nanoparticles are often recognized by the immune system and rapidly cleared from the body. Efforts to extend their residence time in vivo have focused on modifying particle surfaces to evade the body’s natural defenses. Polyethylene glycol (PEG) is currently the gold standard for such nanoparticle stealth coating, but the recent observation of an anti-PEG immunological response has spurred the search for improvements. To address this challenge, researchers have looked to nature, which has created the ideal drug-delivery vehicle — red blood cells (RBCs). Would you like to access the complete CEP Article? No problem. You just have to complete the following steps. You have completed 0 of 2 steps. Log in You must be logged in to view this content. Log in now. AIChE Membership You must be an AIChE member to view this article. Join now. Copyright Permissions: Would you like to reuse content from CEP Magazine? It’s easy to request permission to reuse content. Simply click here to connect instantly to licensing services, where you can choose from a list of options regarding how you would like to reuse the desired content and complete the transaction.