Living cells produce a variety of macromolecules, including proteins, nucleic acids, phospholipids, and carbohydrates, that serve as functional nanomaterials which self-assemble into cellular components. These components then carry out a diverse array of highly specific cellular functions (catalysis, transport, sensing, signaling, partitioning, structural reinforcement etc.) needed to sustain life. The same biologically derived macromolecules, or synthetic analogs that mimic their structure or function, can be used to assemble nanostructured biomimetic interfaces that mimic the functionality of cellular components. This talk will describe examples of such interfaces and illustrate how they may be used for sensing and catalytic applications.
Dr. R. Mark Worden is a Professor in MSU’s Department of Chemical Engineering and Materials Science and Associate Chair of MSU’s Biomedical Engineering Department. His training includes a bachelor’s degree with a double major in chemistry and cell biology, and master’s and doctoral degrees in chemical engineering. Dr. Worden has developed several multi-investigator, interdisciplinary initiatives that integrate research and education. With funding from the Department of Education, he established one interdisciplinary graduate training program on Bioelectronics and another on Technologies for a Biobased Economy. With funding from the National Science Foundation, he developed MSU’s Multidisciplinary Bioprocessing Laboratory course, and with funding from the State Department, he co-developed a three-week training program for Russian bioscientists entitled “Fermentation Pilot-Plant Training for Sibbiopharm Staff”. His research lab uses nanostructured biointerfaces containing biologically active components (enzymes, antibodies, and lipid bilayers) to develop sensing devices and investigate nanotoxicity. His lab also develops multiphase biocatalytic processes based on either microbial fermentations or enzymatic bioconversions. His research has led to over 10 patents issued and pending on topics including microbiosensors, bioelectronics, and bioprocesses to produce high-value products.
Free and open to the public
Light snacks at 6:00 PM while they last
Seminar starts at 7:00 PM
The lecture qualifies for one professional development hour. CEH certificates are needed for licensed Professional Engineers to maintain their license and certificates will be provided to interested attendees.