Relating Surface Viscosity to Monolayer Packing In Model Phospholipid Films Using Active Microrheology

Engineering Sciences and Fundamentals
2011 AIChE Annual Meeting
AIChE Annual Meeting
October 16, 2011 - 8:00pm

The reorientation of a magnetic nickel nanorod placed at the air/phospholipid interface is used to calculate the surface viscosity of spread monolayers of phospholipids, dipalmitoyl phosphatidyl choline (DPPC) and dimyristoyl phosphatidyl ethanolamine (DMPE). While surface viscosity was found to depend on the surface pressure in both lipids, we detect an order of magnitude higher surface viscosity for DMPE films even in the so called liquid coexistence region. This difference is higher than that reported at higher surface pressures and is attributed to the smaller headgroup size of DMPE. The smaller size of the PE head group increases the ability of the lipid molecules to pack into more organized domains at all surface pressures. The minute changes in the morphology of the lipid film are more significant at the lower surface pressures, which contributes to a higher surface viscosity difference. Thus microrheology presents an insight into the degree of lipid organization at the air/water interface, as well as the dependence of surface viscosity on the phase and morphology of the resulting two dimensional interfacial films.
Professional Development Hours
0.5 PDHs
You will be able to download and print a certificate for these PDH credits once the content has been viewed. If you have already viewed this content, please click here to login.

Would you like to access this content?

No problem. You just have to complete the following steps.

You have completed 0 of 2 steps.

  1. Log in

    You must be logged in to view this content. Log in now.

  2. Purchase Technical Presentation

    You must purchase this technical presentation using one of the options below.
    If you already purchased this content recently, please click here to refresh the system's record of ownerships.


Credits 0.5 Use credits
List Price $25.00 Buy now
AIChE Members $15.00 Buy now
AIChE Undergraduate Student Members Free Free access
AIChE Graduate Student Members Free Free access