Metabolic Engineering

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Genomatica: 15 Year Journey (and counting)

Conference Presentation
Metabolic Engineering Conference
June 15, 2014
As a founder and CEO, Christophe Schilling has led Genomatica from a developer of metabolic engineering tools to a position of leadership in biotech...

CEP: News Update

May
2017
News Update
4D Printing Creates Shape-Shifting Materials Scientists at Georgia Institute of Technology and Singapore Univ. of Technology and Design have developed a way to 3D-print objects that can easily change shape when they are heated. The process could...

Advancing the Design-Build-Test Cycle for Metabolic Engineering of Yeast

Archived Webinar
Feb 24, 2016
Metabolic Engineering relies on the Design-Build-Test cycle. This cycle includes technologies like mathematical modeling of metabolism, genome editing and advanced tools for phenotypic characterization. In recent years there have been advances in several of these technologies, which has enabled...

Metabolic Engineering of Bacteria for Production of Oleochemicals

Archived Webinar
Dec 16, 2014
This talk describes pathways for producing high-value commodity chemicals derived from fatty-acids and how we have combined synthetic biology and systems biology to improve oleochemical production in bacteria using sustainable feedstocks. I describe my group’s efforts to engineer artificial...

In Silico Design Tools for Engineering Microbial Biocatalysts

Archived Webinar
Nov 25, 2014
Choosing from the great variety of computational tools now being utilized in the metabolic engineering field can be challenging. You need a computational tool that is able to account qualitatively and quantitatively for a wide range of different data types relevant to biological systems. This...

Cybernetic Approach to Metabolic Modeling

Archived Webinar
Mar 10, 2011
Cybernetic modeling has evolved for well over two decades. This seminar seeks to: (i) introduce its basic tenets, (ii) expound its relationship to other approaches to modeling metabolism, and (iii) to reveal its unique dynamic capabilities. The framework is shown to provide eloquent support for...

Systems Metabolic Engineering

Archived Webinar
Apr 22, 2010
As our concerns on global warming and other environmental problems are increasing, there has been much interest in developing sustainable system for the production of chemicals, fuels, and materials from renewable resources. As microorganisms isolated from nature are often inefficient in performing...

Industrial Systems Biology

Archived Webinar
Aug 25, 2009
Cell factories are used extensively to produce many specific molecules used as pharmaceuticals, fine chemicals, fuels, materials and food ingredients. Through the use of directed genetic modifications of cell factories – an approach referred to as metabolic engineering – it is possible to develop...

Designing Efficient Metabolic Networks for Biofuels Production

Archived Webinar
Jun 25, 2009
Biotechnological processes depend to a large extent on the productivity of the organisms used. Recent advances in systems biology and bioinformatics have made it possible to rigorously analyze the functioning of complex metabolic networks using first principles. Such analysis provides a valuable...

CEP: News Update

November
2016
News Update
Shapeshifting Material Unfolds with Time A new hydrogel material can change shape on its own schedule. Cobalt Gets a New Look for Fischer-Tropsch The Fischer-Tropsch (FT) process converts synthesis gas (a mixture of carbon monoxide and hydrogen)...

Technical Entity Trends: Optimize Production through Metabolic Engineering

November
2016
Technical Entity Trends
Gabriel Levesque-Tremblay
Metabolic engineering is an emerging research field that focuses on optimizing genetic and regulatory processes within cells to increase the cells’ production of a particular substance. Metabolic engineering techniques can be used to redirect...

SBE Conference on Electrofuels Research

August 3, 2011
SBE's Conference on Electrofuels Research will bring together the nation's key players in energy innovation: engineers, scientists, venture capital investors, technology...

Electrofuels: Better Than Biofuels?

4 Comments
August 4, 2011
You know biofuels, but what about electrofuels? Electrofuels are a category of highly efficient biofuel production schemes whereby algae and other microorganisms utilize solar-...

Metabolic Engineering X

December 16, 2013
The Metabolic Engineering Conference is a leading conference for sharing the state-of-the-art developments and achievements made in the field of metabolic engineering over the...

Genomatica: 15 Year Journey (and counting)

Conference Presentation
Metabolic Engineering Conference
June 15, 2014
As a founder and CEO, Christophe Schilling has led Genomatica from a developer of metabolic engineering tools to a position of leadership in biotech...

Catalyzing Commercialization: New Process Makes Spider Silk in Many Forms

August
2016
Catalyzing Commercialization
The strongest fiber found in nature is a silk made by spiders known as orb weavers. Unfortunately, spiders have two flaws: They are territorial and cannibalistic, making it impossible to farm them like silkworms to produce massive quantities of silk...

Optimization Methods in Metabolic Networks

March, 2016
This book provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks. Such analysis and redesign often requires the calculation of product yield, gene essentiality prediction,...

Making Escherichia coli Grow on Methanol

Conference Presentation
AIChE Annual Meeting
November 9, 2015
The quest for using methanol as a substrate to produce useful metabolites such as commodity chemicals, chemical precursors, biopolymers,...

From Metabolic Engineering to Metabolomics and Back

Conference Presentation
AIChE Annual Meeting
November 9, 2015
Metabolic engineering is a field where the level of a specific metabolite is quite obviously a very important thing, because that metabolite is the...

Tools for Engineering Non-Growth Metabolism

Conference Presentation
AIChE Annual Meeting
November 9, 2015
Stationary phase metabolism that is not carbon-limited is ideal for metabolic engineering. Without cell growth, feedstocks can be efficiently...

Model-Driven Minimization of the B. Subtilis Genome

Conference Presentation
AIChE Annual Meeting
November 7, 2010
Bacillus subtilis is a gram positive, sporulating bacteria often utilized in industry as a producer of high quality enzymes and proteins [1]. The...
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