Share Terry McMahonMarch, 2013If you manage to stay afloat long enough, past associations inevitably resurface. At a recent Société de Chimie Industrielle luncheon, I reconnected with a client who I hadn’t seen in almost 30 years. In 1983, I was retained by an investment banker to evaluate the commercial prospects of BioChem Technology, a firm founded by William B. Armiger operating in an industrial park outside of Philadelphia, PA. BioChem primarily made tools for biotech manufacturers, which was virgin territory 30 years ago. One tool caught my fancy — an optical probe for fermentation vessels. The probe, called FluoroMeasure, was designed to monitor a fluorescent marker closely associated with fermentation broth metabolism. Fermentor respiration rates have been monitored via offgas analysis with onstream mass spectrometers for several decades, but in situ mobile-phase assays are still rare. FluoroMeasure was 20 years ahead of the U.S. Food and Drug Administration’s process analytical technology (PAT) Initiative. Would you like to access the complete CEP Article? No problem. You just have to complete the following steps. You have completed 0 of 2 steps. Log in You must be logged in to view this content. Log in now. AIChE Membership You must be an AIChE member to view this article. Join now. Copyright Permissions: Would you like to reuse content from CEP Magazine? It’s easy to request permission to reuse content. Simply click here to connect instantly to licensing services, where you can choose from a list of options regarding how you would like to reuse the desired content and complete the transaction.