Deconstruction of lignocellulosic biomass into fermentable sugars is among the major challenges in producing cellulosic biofuels and biobased products. Current pretreatment methods to liberate solid cellulose are expensive, accounting for as much as 30% of the cost of producing cellulosic biofuels. Most pretreatments do not completely fractionate cellulose and lignin, the latter of which interferes with enzymatic hydrolysis.
