Since the Kellogg lab opened in 2019 at Cornell University, they have contributed significantly to mechanistic understanding of DNA transposons using cryo-EM. Their major goal is to understand how transposons reshape genomes and how transposons can be repurposed as genome-editing tools. The Kellogg lab's first significant scientific contribution includes the structural and mechanistic characterization of a unique cut and paste transposase, called the P-element transposase, published in NSMB (2019). The Kellogg lab also formulated the first model of transposition that could explain the...Read more
Anna Kajaste-Rudnitski is a Group Leader at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), OSR, in Milan. Merging her background in innate immunity and virology with acquired competences in gene therapy, Dr. Kajaste-Rudnitski’s team studies the molecular mechanisms of host-vector interplay and innate immunity in the context gene therapy applications and autoinflammatory diseases. Their long-term goal is to provide insight into how pathogen recognition and consequent innate immune signaling may affect efficacy and safety of gene therapy approaches in clinically relevant...Read more
She has been working in the field of Fanconi anemia (FA) gene therapy for more than 20 years. Her studies in gene therapy for Fanconi anemia include the design of a new lentiviral vector that received the Orphan Drug Designation both by the EMA and FDA and the first demonstration that a short transduction protocol allows the engraftment of corrected cells from FA patients in immunodeficient mice. Now she is deeply involved as associated investigator in two different clinical trials focused on the correction of HSCs from...Read more
The measurement of low ammonia (NH3) concentrations is a key objective for the safety of personnel and industrial infrastructure. Learn the strengths, weaknesses, and advancements of some of the most common gas sensing technologies used for detecting ammonia
Join our virtual presentation and panel discussion on unconscious bias and why it matters in STEM and Engineering. Welcome & Introduction Cynthia Murphy-Ortega, Manager of University Partnerships...
