May 2012 | AIChE

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May 2012

In Silico Modeling of the Immune Response Network: Influenza Immune-Escape Strategies and Implications in Influenza Drug Research

Conference Presentation
AIChE Annual Meeting
November 9, 2010
Recent evidence suggests that an overly ambitious immune response may be the primary factor that determines influenza severity [1], yet the...

Identification of Families of Signal Transduction Models Using Pareto Optimal Ensemble Techniques (POETs)

Conference Presentation
AIChE Annual Meeting
November 9, 2010
Mathematical modeling of complex signal transduction and gene expression programs is an emerging tool for understanding disease mechanisms. However,...

Cell Population Heterogeneity and Mass Transport Dynamics Modulate Tissue Regeneration Processes

Conference Presentation
AIChE Annual Meeting
November 9, 2010
A better understanding of the complex interplay between cell population dynamics and mass transport is necessary for overcoming the barriers that...

Omics Analysis of Agrobacterium Sp. Uncovers Regulatory Factors for Polysaccharide Biosynthesis

Conference Presentation
AIChE Annual Meeting
November 8, 2010
Microbial polysaccharides are primary cellular components and integral to many cellular functions including cell adhesion, biofilm formation,...

Integration of Signaling Networks with Differential Gene Regulation Data Using a Probabilistic Pathway Impact Analysis Approach

Conference Presentation
AIChE Annual Meeting
November 9, 2010
The objective of the present study is to integrate the information on intracellular signaling network structures with large-scale gene expression...

Novel, Synthetic, Tetracycline-Inducible Transcription Regulators for E. Coli

Conference Presentation
AIChE Annual Meeting
November 7, 2010
We are designing, constructing and characterizing novel synthetic gene regulators. These regulators range from individual inducible fusion protein...

Modeling Eukaryotic Unfolded Protein Response and Its Role in Cellular Stress

Conference Presentation
AIChE Annual Meeting
November 7, 2010
Malfunctions in the folding state of critical proteins have been linked with cancer, diabetes and other diseases. Proteins requiring complex post-...

A System Approach to Astrocytoma Progression

Conference Presentation
AIChE Annual Meeting
November 8, 2010
Astrocytomas are brain cancers that account for 75% of neuroepithelial tumors. Accurate diagnosis is required for adequate treatment and assessing...

Study of Mixotrophic and Photoheterotrophic Metabolisms in Cyanothece Sp. ATCC 51142 Via Isotopomer-Assisted Metabolite Analysis

Conference Presentation
AIChE Annual Meeting
November 10, 2010
The unicellular diazotrophic cyanobacterium, Cyanothece sp. ATCC 51142 (Cyanothece 51142), is able to grow aerobically in nitrogen-fixing conditions...

Genomic Approaches to Evolutionary History of Primate Cytochromes c

Conference Presentation
AIChE Annual Meeting
November 8, 2010
Cytochrome c (cyt c) is a highly conserved protein among eukaryotes, mainly owing to its pivotal role in two crucial cellular processes: apoptosis...

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