Experimental & Computational Tools for Engineering Biomolecules

Monday, January 14, 2013, 3:15pm-5:40pm EST

Session Co-Chairs:

  • Erick Althoff, Arzeda Corp
  • Jennifer Cochran, Stanford University

Invited Speakers:

  • Ravi Radhakrishnan, University of Pennsylvania: Model-Based Design and Optimization of Functionalized Nanocarriers for Vascular Targeted Drug Delivery
  • Charlie Boone, University of Toronto- The Genetic Landscape of a Cell
  • Jim Swartz, Stanford University- Biomolecular Engineering Toward Novel, Potent, and Broadly Protective VLP-Based Influenza Vaccines

Oral Presentations:

  • Charles Gersbach, Duke University: Engineering Synthetic DNA-Binding Proteins for Targeted Gene Regulation and Genome Editing
  • Marlene Belfort, University at Albany: Inteins as tools and targets

Charlie Boone

Dr. Boone received his Ph.D. in molecular biology in 1989 from McGill University in Montreal, Canada. He then did postdoctoral research in yeast genetics at the Institute of Molecular Biology, University of Oregon, in Eugene and, in 1993, founded his own research lab at the Institute of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada. In 1999, he received the Ontario Government’s Premier's Research Excellence Award. He is also a recipient of the William E. Rawls Award for Research Excellence of the National Cancer Institute of Canada, the 2003 Merck Frosst...

Ravi Radhakrishnan

Ravi's research interests lie at the interface of chemical physics and molecular biology. His lab's goal is to provide atomic and molecular level characterization of complex biomolecular systems and formulate quantitatively accurate microscopic models for predicting the interactions of various therapeutic agents with innate biochemical signaling mechanisms. To do so, they employ several computational algorithms ranging from techniques to treat electronic structure, molecular dynamics, Monte Carlo simulations, stochastic kinetic equations, and complex systems analyses in conjunction with...