Biomedical Engineering

Your Experiences Leave a Mark

February 13, 2018
Epigenetics — the study of how our actions and experiences mark or modify our DNA — can explain some unusual genetic findings.

Chemical Engineers as Biomedical Innovators

Archived Webinar
Aug 7, 2013
The design of biomedical materials is rooted in principles of chemical engineering. This presentation describes the connections between chemical engineering and biomedical innovations, and discusses the translation of novel materials into clinical applications.

Microengineered Hydrogels for Stem Cell Bioengineering and Tissue Regeneration

Archived Webinar
Aug 23, 2011
Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various tissue engineering...

Engineering and Health Care

Archived Webinar
May 16, 2011
Dr. Langer discusses the involvement of engineering in health care, from the discovery of the first angiogenesis inhibitors to the development of controlled drug delivery systems and the foundation of tissue engineering.

A System Approach to Astrocytoma Progression

Conference Presentation
AIChE Annual Meeting
November 8, 2010
Astrocytomas are brain cancers that account for 75% of neuroepithelial tumors. Accurate diagnosis is required for adequate treatment and assessing...

Multi-Scale Agent-Based Modeling of Human Endotoxemia

Conference Presentation
AIChE Annual Meeting
November 8, 2010
The systemic inflammatory response syndrome (SIRS) often accompanies critical illness but is evoked by many stimuli e.g. infection, trauma, invasive...

Body-on-a-Chip -- A Tool for Predictive Pharmacology/Toxicology

Archived Webinar
Mar 31, 2009
In this presentation, Professor Mike Shuler details his work to understand the response of the human body to various pharmaceutical and environmental chemicals using a combination of whole body modules and micro models Professor Shuler’s research focuses on microfabricated devices combined with...

Systems Biology: Open Challenges and Opportunities for Chemical Engineers

Archived Webinar
Jan 20, 2009
Systems biology involves the analysis of multiple scales of 'control' in biological networks, from the regulation of gene transcription to the homeostatic regulation of metabolism in the whole body. These natural control circuits are paragons of optimality: over millennia, they have been honed to...

November 2017 CEP Preview

November 13, 2017

Chemical engineers' response to the addiction epidemic, cogeneration operation basics, an overview of Colombia's chemical industry, and more.

Computational Protein Engineering

October
2017
SBE Special Section
Robert Pantazes
Proteins could transform the chemical process industries if they could be engineered to facilitate the production of biofuels, molecular medicines, and other specialty chemicals. This reality is nearing as expanded knowledge of proteins and improvements in computational tools are making it possible to design specific protein structures and functions.

Engineering Cancer-Fighting T Cells

October
2017
SBE Special Section
Eugenia Zah, Yvonne Y. Chen
Adoptive T-cell therapy is a personalized cancer treatment that has the potential to cure previously untreatable malignancies. Researchers are applying techniques in biomolecular engineering and synthetic biology to the development of next-generation therapeutic T cells with improved safety and efficacy against a variety of cancers.

There’s Plenty of Room at the Bottom of a Cell

October
2017
SBE Special Section
Angela R. Wu, Lei Yu
Single-cell RNA sequencing is giving engineers and scientists the ability to better understand and manipulate the smallest unit of a living organism — the single cell. This technique has already ushered in breakthroughs in biology and medicine. However, challenges and opportunities abound.

SBE Special Section: Biomolecular Engineering (full 34-page section)

October
2017
SBE Special Section
SBE Update: The Many Applications of Biomolecular Engineering; A Materials Approach to Vaccines as Therapies; Engineering Cancer-Fighting T Cells; There's Plenty of Room at the Botton of a Cell; Computational Protein Engineering; Plant Metabolic Engineering for Chemicals, Fuels, and Precursors

Profile: Developing Novel Solutions to Improve Patient Care

June
2017
Profile
Lonnie Shea, a professor and chair in the Dept. of Biomedical Engineering at the Univ. of Michigan, is an internationally recognized researcher whose work spans the fields of regenerative medicine, biomaterials, and gene and drug delivery. His research seeks to advance technologies and solutions at the interface of engineering and medicine.

Little Bio-Machinery to Solve Grand Challenges

January 3, 2017
As we approach ICBE 2017, which begins this weekend in San Diego, we look back at some of the exciting research that figured among 2016's highlights and look forward to the new developments to be unveiled at ICBE 2017.
Magnified view of the Drosophila melanogaster fruit fly

Fruit Fly Finding Could Fight Human Cancers

January 26, 2017

Researchers at Indiana University Bloomington have discovered that a molecule related to some forms of cancer and neurodegenerative disorders is also present in developing Drosophila melanogast

Study Points to Therapeutic Cancer Vaccine

December 30, 2016

Researchers at the University of Michigan have had a significant breakthrough in creating a customized therapeutic vaccine for treating colon and melanoma cancer tumors in mice.

A Hitchhiker’s Guide to Drug Delivery [On Location]

1 Comment
November 6, 2012

A novel drug delivery technique has nanoparticles thumbing for a ride aboard red blood cells. This promising work comes from researchers at the University of California, Santa Barbara, who presented their findings at the 2012 Annual Meeting in Pittsburgh.

First the Google Glass, and Now Google Contacts?

January 21, 2014

Unlike the Google Glass, Google's contact lens should not be scary to anyone. Developed as a blood glucose monitoring device, millions of diabetics could benefit from the lens.

Columbia University Sues Illumina over DNA Sequencing Patents

April 17, 2012

Columbia professor Jingyue Ju, early co-inventor of the fluorescence energy transfer labeling technology that enabled the development of high-throughput DNA sequencers, finds himself in the middle of a patent protection lawsuit that will affect some of the world's biggest pharmaceutical companies.

Google Aims to Spot Cancer and Heart Disease with Wristband

November 5, 2014

Google has announced that one of the special projects it's working on entails creating a wristband that will perform diagnostic tests on the wearer, such as looking for indicators of cancer and heart disease, among other ailments.

New In Vitro Technique Holds Promise for Treating Infertility

November 9, 2012

For young women facing a cancer diagnosis, the fear of chemotherapy-induced sterility often leads to seeking fertility-protective measures. Current methods of fertility preservation, however, can delay cancer treatment and come with the risk of reintroducing cancer cells later. Today, a new technique for in vitro culture and maturation of ovarian follicles holds promise for treating infertility in these cases.

Synthetic Membranes that Grow Like Living Cells

June 24, 2015

This week, a group of chemists and biologists working at the University of California San Diego announced that they have designed and synthesized an artificial cell membrane capable of sustaining c

A Universal Anesthesia Machine that Works Without Power

February 8, 2012

Ted Talks presents Erica Frenkel, a program officer at UAM Global, the company that offers a cost-effective scaleable solution for putting anesthesia machines that works in rugged environments often associated with developing countries. The machine is in 13 hospitals and 4 countries and new partnerships with NGOs will likely increase that number. Watch the video

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