Biomedical Engineering

CEP: News Update

August
2018
News Update
New CRISPR Findings Raise Concerns Before Technology’s Clinical Debut A pair of studies that investigated the effect of CRISPR-Cas 9 on a key protein that regulates cell growth and protects against cancer has sent shockwaves through the growing...

CEP: News Update

July
2018
News Update
Nanomaterials Restore Aged Canvases Researchers at Chalmers Univ. of Technology in Göteborg, Sweden, have developed a new method to provide structural support to canvas using nanomaterials. The method, called consolidation, treats the degraded...

Consider a Career in Biotech

June 26, 2018

Looking for a promising career direction? Biotech is a vast and diverse field and has growing opportunities.

May 2018 CEP Preview

May 18, 2018

This month, brush up on the essentials of continuous evaporation, learn new uses for hydrofoil impellers, enjoy the special section on translational medicine, and more.

Recent Advances in Hydrogels for Tissue Engineering

May
2018
SBE Special Section
Samad Ahadian, Houman Savoji, Ali Khademhosseini
Hydrogels could play an important role in the fabrication of functional tissues for regenerative medicine. This article describes the developments in polymer chemistry, nanomaterials, molecular biology, and microscale technologies that are spurring advances in hydrogel fabrication.

Curtailing Antibiotic Use in Livestock Production

May
2018
SBE Special Section
Yiannis N. Kaznessis
For decades, livestock producers have routinely administered antibiotics to animals to make them grow faster or as a preventive treatment against disease. This may be contributing to the increasing number of humans being infected by antibiotic-resistant bacteria. Researchers are now searching for viable alternatives.

SBE Special Section: Translational Medicine (Complete 44-Page Section)

May
2018
SBE Special Section
Engineering the Precise Translation of Novel Medicines; From Data to Diagnosis: The Search for Biochemical Markers of Autism Spectrum Disorder; Designing Drug Delivery Systems for Articular Joints; Curtailing Antiobiotic Use in Livestock Production; Recent Advances in Hydrogels for Tissue Engineering; Going Small is Big: Creating Organoids for Regenerative Medicine; Direct Production of Engineered Cardiac Tissue within Hybrid Biomaterials

Designing Drug Delivery Systems for Articular Joints

May
2018
SBE Special Section
Brett C. Geiger, Alan J. Grodzinsky, Paula Hammond
No disease-modifying drug exists for osteoarthritis due to poor drug delivery within joints. Engineered biomaterials could address this challenge by improving the duration and targeting of therapies.

Direct Production of Engineered Cardiac Tissue within Hybrid Biomaterials

May
2018
SBE Special Section
Morgan Ellis, Elizabeth Lipke
The human heart contains highly specialized cells that are especially vulnerable to damage because they lack regenerative capabilities. This article describes a novel method for encapsulating and directly differentiating induced pluripotent stem cells in hybrid biomaterials to form cardiac tissue.

Engineering the Precise Translation of Novel Medicines

May
2018
SBE Special Section
The field of bioengineering has placed engineers at the frontier of human health. In fact, medical schools at Univ. of Illinois Urbana-Champaign, Texas A&M, and other universities are developing programs with an “engineering-centric medicine” approach.

Going Small Is Big: Creating Organoids for Regenerative Medicine

May
2018
SBE Special Section
Ogechi Ogoke, Mitchell H. Maloy, Saber Meamardoost, Natesh Parashurama
Organoids are a promising tool to replicate key structural and functional features of human organs. Recent developments in organoids to model the liver, biliary tract, and pancreas have the potential to advance regenerative medicine.

Books: April 2018

April
2018
Books
The Future of Humanity: Terraforming Mars, Interstellar Travel, Immortality, and Our Destiny Beyond Earth Michio Kaku, Doubleday, New York, NY, $29.95, 368 pages, Feb. 2018, ISBN: 978-0-385-54276-0 Moving human civilization beyond Earth’s bounds is...

Your Experiences Leave a Mark

February 13, 2018

Epigenetics — the study of how our actions and experiences mark or modify our DNA — can explain some unusual genetic findings.

Chemical Engineers as Biomedical Innovators

Archived Webinar
Aug 7, 2013
The design of biomedical materials is rooted in principles of chemical engineering. This presentation describes the connections between chemical engineering and biomedical innovations, and discusses...

Engineering and Health Care

Archived Webinar
May 16, 2011
Dr. Langer discusses the involvement of engineering in health care, from the discovery of the first angiogenesis inhibitors to the development of controlled drug delivery systems and the foundation...

Multi-Scale Agent-Based Modeling of Human Endotoxemia

Conference Presentation
AIChE Annual Meeting
November 8, 2010
The systemic inflammatory response syndrome (SIRS) often accompanies critical illness but is evoked by many stimuli e.g. infection, trauma, invasive...

A System Approach to Astrocytoma Progression

Conference Presentation
AIChE Annual Meeting
November 8, 2010
Astrocytomas are brain cancers that account for 75% of neuroepithelial tumors. Accurate diagnosis is required for adequate treatment and assessing...

November 2017 CEP Preview

November 13, 2017

Chemical engineers' response to the addiction epidemic, cogeneration operation basics, an overview of Colombia's chemical industry, and more.

Computational Protein Engineering

October
2017
SBE Special Section
Robert Pantazes
Proteins could transform the chemical process industries if they could be engineered to facilitate the production of biofuels, molecular medicines, and other specialty chemicals. This reality is nearing as expanded knowledge of proteins and improvements in computational tools are making it possible to design specific protein structures and functions.

Engineering Cancer-Fighting T Cells

October
2017
SBE Special Section
Eugenia Zah, Yvonne Y. Chen
Adoptive T-cell therapy is a personalized cancer treatment that has the potential to cure previously untreatable malignancies. Researchers are applying techniques in biomolecular engineering and synthetic biology to the development of next-generation therapeutic T cells with improved safety and efficacy against a variety of cancers.

There’s Plenty of Room at the Bottom of a Cell

October
2017
SBE Special Section
Angela R. Wu, Lei Yu
Single-cell RNA sequencing is giving engineers and scientists the ability to better understand and manipulate the smallest unit of a living organism — the single cell. This technique has already ushered in breakthroughs in biology and medicine. However, challenges and opportunities abound.

SBE Special Section: Biomolecular Engineering (full 34-page section)

October
2017
SBE Special Section
SBE Update: The Many Applications of Biomolecular Engineering; A Materials Approach to Vaccines as Therapies; Engineering Cancer-Fighting T Cells; There's Plenty of Room at the Botton of a Cell; Computational Protein Engineering; Plant Metabolic Engineering for Chemicals, Fuels, and Precursors

Profile: Developing Novel Solutions to Improve Patient Care

June
2017
Profile
Lonnie Shea, a professor and chair in the Dept. of Biomedical Engineering at the Univ. of Michigan, is an internationally recognized researcher whose work spans the fields of regenerative medicine, biomaterials, and gene and drug delivery. His research seeks to advance technologies and solutions at the interface of engineering and medicine.
Magnified view of the Drosophila melanogaster fruit fly

Fruit Fly Finding Could Fight Human Cancers

January 26, 2017

Researchers at Indiana University Bloomington have discovered that a molecule related to some forms of cancer and neurodegenerative disorders is also present in developing Drosophila

Little Bio-Machinery to Solve Grand Challenges

January 3, 2017

As we approach ICBE 2017, which begins this weekend in San Diego, we look back at some of the exciting research that figured among 2016's highlights and look forward to the new developments to be unveiled at ICBE 2017.

Study Points to Therapeutic Cancer Vaccine

December 30, 2016

Researchers at the University of Michigan have had a significant breakthrough in creating a customized therapeutic vaccine for treating colon and melanoma cancer tumors in mice.

Technology Can Stop the Zika Virus, but Should It?

February 9, 2016

If you could eradicate the Aedes aegypti mosquito responsible for spreading the Zika virus in the Americas, would you? And should you? Those are some of the big questions being tossed about among biologists, ecologists, public health experts, and others today because the technology exists to bid farewell to the pesky mosquito.

Pharma Turns to Gut for New Drugs

January 25, 2016

The past few years have been full of stories about how a number of serious conditions could be treated or cured by introducing certain bacteria to the digestive system.

Polymer Nanotubes that Resemble Nerve Structures

August 26, 2015

Researchers at Sandia National Laboratories have created linkages of polymer nanotubes that resemble the structure of a nerve and are capable of transmitting electrical impulses.

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