Biotechnology Progress, July/August 2020, Volume 36, Issue 4

Issue Information
Biochemical characterization and structural insights into the high substrate affinity of a dimeric and Ca2+ independent Bacillus subtilis α - amylase
Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position
Clearance of porcine circovirus and porcine parvovirus from porcine - derived pepsin by low pH inactivation and cation exchange chromatography
Designing a new dimerized anti human TNF - α aptamer with blocking activity
Improving product quality and productivity of bispecific molecules through the application of continuous perfusion principles
Feeding tricarboxylic acid cycle intermediates improves lactate consumption and antibody production in Chinese hamster ovary cell cultures
Characterization of three - dimensional rat central nervous system culture maturation, with applications to monitor cholinergic integrity
Analysis of chemometric models applied to Raman spectroscopy for monitoring key metabolites of cell culture
Multiplexed clonality verification of cell lines for protein biologic production
Dewatering of algal suspension using microfiltration with cross flow in the presence of magnetite as a filter aid
The use of catechins in Chinese hamster ovary cell media for the improvement of monoclonal antibody yields and a reduction of acidic species
Comparison of mono - rhamnolipids and di - rhamnolipids on microbial enhanced oil recovery (MEOR) applications
Microbial β - Galactosidases of industrial importance: Computational studies on the effects of point mutations on the lactose hydrolysis reaction
A novel approach to evaluate ELISA antibody coverage of host cell proteins-combining ELISA - based immunocapture and mass spectrometry
Straightforward method for calibration of mechanistic cation exchange chromatography models for industrial applications
Selective binding of Ni2+ and Cu2+ metal ions with naphthazarin esters isolated from Arnebia euchroma
Emulsion - based encapsulation of pluripotent stem cells in hydrogel microspheres for cardiac differentiation
Innovative development of membrane sparger for carbon dioxide supply in microalgae cultures
Feasibility of spectral pH measurement during the low - pH virus inactivation step of continuous therapeutic antibody production
Optimization of β - mannanase production by Bacillus subtilis US191 using economical agricultural substrates
Transfection of glycoprotein encoding mRNA for swift evaluation of N - glycan engineering strategies
Immobilization of horseradish peroxidase onto Purolite® A109 and its anthraquinone dye biodegradation and detoxification potential
Preparation, statistical optimization and characterization of poly(3 - hydroxybutyrate) fermented by Cupriavidus necator utilizing various hydrolysates of alligator weed (Alternanthera philoxeroides) as a sole carbon source
Purification of animal immunoglobulin G (IgG) using peptoid affinity ligands
Model - based design and control of a small - scale integrated continuous end - to - end mAb platform