Predictive Scale-up/Scale-Down for Production of Pharmaceuticals and Biopharmaceuticals
AIChE Annual Meeting
2014
2014 AIChE Annual Meeting
Pharmaceutical Discovery, Development and Manufacturing Forum
Oral
203
Hilton Atlanta
Thursday, November 20, 2014 - 8:30am to 11:00am
Chair(s)
Co-chair(s)
Batch processing in the Pharmaceutical Industry involves a series of unit operations where the synthesis and downstream processing of the chemical or microbiological product takes place in conjunction with the transfer of mass, heat and momentum transfer. All of these processes are scale dependent and typically involve scaling-up from lab equipment to mini-plant and eventually to full scale commercial operation. Similarly operational issues experienced at full scale manufacturing (poor quality, yield, safety, etc.) require a systematic scale-down approach to the lab scale in order to reproduce and analyze manufacturing problems before implementing solutions. Chemical engineers working in the industry today are faced with the challenge to appropriately plan experiments in the lab in order to tackle such problems using predictive, first-principles based modeling as guide. This session is meant to invite papers that cover both theoretical and applied aspects of such scale-up/scale-down analysis. Papers covering both drug substance and drug product applications are also encouraged.
Presentations
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Pricing
Individuals
2014 AIChE Annual Meeting
AIChE Pro Members | $150.00 |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $225.00 |
Non-Members | $225.00 |
Pharmaceutical Discovery, Development and Manufacturing Forum only
AIChE Pro Members | $100.00 |
Food, Pharmaceutical & Bioengineering Division Members | Free |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $150.00 |
Non-Members | $150.00 |