(416f) Nanobiocatalysis Based on Enzyme Crosslinking

The specificity of enzymes promises great improvements in a variety of their potential applications. However, the short lifetimes of enzymes frequently limit their usefulness. Recent breakthroughs in nanotechnology have made various nanostructured materials more affordable for a broader range of applications, including enzyme immobilization and stabilization. This presentation will discuss recent developments in nanobiocatalysis to improve the enzyme stability using various nanostructures such as mesoporous materials, nanofibers, nanoparticles, and carbon nanotubes. Nanoscale enzyme reactors in mesoporous media will be discussed in detail together with enzyme coatings on electrospun nanofibers, magnetic nanoparticles, and carbon nanotubes. Stabilized enzyme systems in various nanostructures will make an ideal system for many applications including bioremediation, antifouling, biosensors, bioreactors, microfluidic devices, trypsin digestion, biofuel cells, and bioenergy generation. Several successful examples of nanobiocatalytic applications will be given in this presentation.