Tomer Shlomi

Tomer Shlomi

Associate Professor
Technion Israel Institute of Technology

Tomer's interest in nanotechnology stems from working on characterizing and quantifying metabolic aberrations in cancer cells. Towards this end, he applies high-throughput metabolomics and isotope tracing approaches via high-resolution mass-spectrometry (detecting molecules whose concentration is in a nano-molar scale).

Research

Achieving a system level understanding of cellular metabolism represents a major challenge from a basic science perspective, considering the complexity of the system, involving the joint activity of hundreds or thousands of biochemical reactions. Our group aims to derive a comprehensive and quantitative view of cellular metabolism by combining experimental and computational tools.  Our major experimental platform is metabolomics via mass-spectrometry (LC/MS), enabling the detection and quantification of hundreds of metabolites per biological sample. To facilitate inference of metabolic flux, we employ isotope-tracing techniques and develop novel analytical approaches and algorithms for interpreting generated data. On the computational front, we further specialize in developing methods for analyzing genome-scale metabolic network models via Constraint-Based Modeling (CBM). 

For more information please visit https://rbni.technion.ac.il/node/305