Shaochen Chen | AIChE

Shaochen Chen

University of California San Diego

Dr. Shaochen Chen is a is a Professor and Chair in the Department of NanoEngineering and an Affiliated Professor in the Department of Bioengineering at the University of California San Diego. He is the founding co-director of the Biomaterials and Tissue Engineering Center at UC San Diego. He received his PhD in Mechanical Engineering in 1999 from the University of California, Berkeley. Before joining UC San Diego, Chen had been a Professor and a Pearlie D. Henderson Centennial Endowed Faculty Fellow in Engineering at the University of Texas at Austin from 2001 to 2010. Between 2008 and 2010, he served as the Program Director for the Nanomanufacturing Program in the National Science Foundation (NSF).

Dr. Chen is a pioneer in 3D printing and bioprinting with over 200 peer-reviewed publications. He first initiated a scanningless 3D printing technique termed "micro-stereolithography (µSL)" for projection printing of biomaterials in 2006. Building upon his µSL technique, he invented a dynamic optical stereolithography method (DOPsL) in 2012 (Advanced Materials, 2012). Compared to traditional nozzle-based 3D printing, DOPsL enables 3D printing that is 3,000 times faster in printing speed and 100 times finer in printing resolution (Nature Communications, 2014). He has continued to advance this field by developing a microscale continuous optical bioprinting (µCOB) method for the rapid 3D bioprinting of functional tissues models in mere seconds. Using human induced pluripotent stem cells, he successfully bioprinted functional liver tissues that enable disease modeling and drug screening (PNAS, 2016). Furthermore, by integrating neuron stem cells within a 3D printed biomimetic scaffold, his team has succeeded in the repair of a severely damaged spinal cord in rats to result in significant functional recovery (Nature Medicine, 2019). His ground-breaking work has been reported by The Washington Post, The Wall Street Journal, Forbes, and Yahoo News.

His pioneering work in micro and nanoscale 3D printing and bioprinting established the foundation for the emerging field of biofabrication for tissue engineering and regenerative medicine applications. He founded a startup company, Allegro 3D to commercialize his bioprinting techniques. It is providing transformative solutions to organ/tissue repair and regeneration, accelerating drug toxicity and efficacy testing, and advancing human diseases modeling.

Dr. Chen has received numerous awards, including the NSF CAREER award, ONR Young Investigator award, and NIH Edward Nagy New Investigator Award. In 2017, he received the Milton C. Shaw Manufacturing Research Medal from ASME for his seminal work in 3D printing, bioprinting, and nanomanufacturing. This is the highest award given by ASME to recognize original manufacturing research in the field. Dr. Chen is a Fellow of major societies, including the American Association for the Advancement of Science (AAAS), American Institute for Medical and Biological Engineering (AIMBE), American Society of Mechanical Engineers (ASME), International Society for Optics and Photonics (SPIE), and International Society for Nanomanufacturing (ISNM).