Pin Wang is a Zohrab A. Kaprielian Fellow and Professor of Chemical Engineering and Materials Science and Biomedical Engineering at the University of Southern California. He received his Doctoral Degree in Chemical Engineering from the California Institute of Technology. He is also the Director for the Center for ImmunoEngineering at the Viterbi School of Engineering in the University of Southern California. Dr. Wang as 90 publications and six patents. He has been invited to review several scientific journals, including ACS Nano, Advanced Materials, Biomaterials, Bioengineering and Biotechnology, Blood, Experimental Hematology, Gene Therapy, Human Gene Therapy, Molecular Therapy, Nature Methods, and Molecular Biotechnology, as well as being an ad hoc member of NIH GDD study section (2009-2014) and is currently a standing member in 2015.
Dr. Wang's lab focuses on an emerging field of “immunobioengineering” with the aim of employing engineering tools and principles to quantitatively understand the immune system in health and disease and to develop novel molecular and cellular immunotherapies by precisely modulating disease-specific immune responses. The ongoing research research projects include: 1) exploring various strategies to engineer virus-derived vector systems for dendritic cell-targeted vaccine delivery and oncolytic virus-based immunotherapy; 2) designing and optimizing cellular immunotherapy that is based on molecular engineering of chimeric antigen receptors (CARs); 3) exploring immune cells as drug carriers for targeted delivery of immunomodulatory drugs to enhance cancer immunotherapy; 4) exploring systems biology tools for modeling and understanding details of signaling pathways mediated by designer molecules such as chimeric antigen receptors to activate T cells; 5) developing engineering methods to improve adeno-associated virus (AAV)-based gene delivery.