Albert Jeltsch finished his PhD working on the mechanism of restriction endonucleases at University Hannover in 1994. Afterwards he started to study DNA methyltransferases at Justus-Liebig University Giessen and at Jacobs University Bremen. Since 2011, he is professor of Biochemistry at the University Stuttgart. In 1999, he received the Gerhard-Hess award of the DFG for his work on mammalian DNA methyltransferases. In 2001, he received the BioFuture award of the BMBF for a project aiming at DNA methylation editing. The group of Prof. Jeltsch investigate the structure and mechanism of bacterial and mammalian DNA methyltransferases. They have long standing expertise in the field of rational and evolutionary protein design of DNA interacting enzymes and in the design of chimeric methylation enzymes for gene regulation in eukaryotic cells. In addition, they study the specificity and activity of histone methyltransferases and methyl lysine reading domains and provided seminal discoveries in both fields. Their work has been published in more than 200 papers. Prof. Jeltsch is in the editorial board of several journals including Scientific Reports, ChemBioChem, Epigenomics, Frontiers in Genetics, PLOS one and BMC Biochemistry.