My background and training is in computational biology, microbiology, and immunology. During my PhD thesis work with Matthew Meyerson and Wendy Garrett, we discovered an association between colorectal cancer and the gut microbiome constituent Fusobacterium nucleatum. We demonstrated that Fusobacterium accelerated intestinal tumorigenesis by a mechanism involving altered immune cell recruitment to the tumor, which we established after developing a mouse model with a humanized microbiome. As a postdoctoral fellow at Broad Institute working with Ramnik Xavier and Curtis Huttenhower, I worked...Read more
