November 2014 | AIChE

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November 2014

Applying PAT for Pharmaceutical Powder Blending Process: Challenges and Opportunities

Conference Presentation
AIChE Annual Meeting
November 19, 2014
Pharmaceutical powder blending presents challenges for high risk category products such as highly potent drugs, low dose drugs, drugs with narrow...

In-Process Particle Size Analysis for Commercial Pharmaceutical Manufacturing

Conference Presentation
AIChE Annual Meeting
November 19, 2014
Particle sizes of drug substances, excipients, and intermediates are of great importance for most of solid oral dosage forms and are traditionally...

Optimal CO2 Capture and Utilization (CCU) Supply Chain Network for Enhanced Oil Recovery

Conference Presentation
AIChE Annual Meeting
November 19, 2014
More than 60% of the total anthropogenic CO 2 emissions in the U.S. are emitted from stationary sources such as power plants, iron and steel...

QbD in Development of Film Coated Tablets: A Risk Assessment Based Doe Towards a Robust Product and Process

Conference Presentation
AIChE Annual Meeting
November 19, 2014
The principles of Quality by Design (QbD) were applied during the formulation development of a film-coated tablet. A risk based approach was used to...

Excipient-Process Interactions and Their Effects on Tablet Compaction and Film Coating

Conference Presentation
AIChE Annual Meeting
November 19, 2014
When formulating drugs with low aqueous solubility and high sticking tendency, it is a common practice to include sodium lauryl sulfate (surfactant)...

Quality-By-Design Evaluation of an Immediate Release Tablet Platform

Conference Presentation
AIChE Annual Meeting
November 19, 2014
Excipient variability, and its impact on drug product performance, has been previously examined with risk-based, experiment-based, and data-based...

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